Central Nervous System News and Research

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Glial cells in the heart play critical role in cardiac development and function

Glial cells in the heart help regulate heart rate and rhythm, and drive its development in the embryo, according to a new study publishing November 18th in the open-access journal PLOS Biology by Nina Kikel-Coury, Cody Smith and colleagues at the University of Notre Dame.

19 Nov 2021

Genomic changes in advanced tumors reveal interactions with treatment

A novel way to look at cancer treatment resistance offers the possibility for identifying genetic mechanisms involved and alternative treatment approaches.

17 Nov 2021

Tough protein connects directly with neurons to cause damaging inflammatory reaction in the brain

Neuroinflammatory diseases, including Alzheimer's disease and traumatic brain injury, have been linked to deposits of a tough protein known as fibrin, derived from the blood clotting factor fibrinogen.

9 Nov 2021

CHOP-led network aims to unlock the genetic mysteries behind pediatric brain tumors

Unlocking the genetic mysteries behind pediatric brain tumors is at the heart of the mission of the Center for Data Driven Discovery in Biomedicine (D3b) at Children's Hospital of Philadelphia.

3 Nov 2021

Monoclonal antibodies mitigate inflammatory consequences of SARS-CoV-2 exposure in macaques

Monoclonal antibodies protected aged, diabetic rhesus macaque monkeys from disease due to SARS-CoV-2 and reduced signs of inflammation, including in cerebrospinal fluid, according to a new study from researchers at the University of California, Davis.

From The University of California, Davis 2 Nov 2021

Delta opioid receptor agonists modulate immune responses to ameliorate colonic inflammation

Opioids are a class of substances that control sensations such as pain and emotions in animals. While plant-derived opioid narcotics such as morphine are the most well-recognized, other opioid molecules like endorphins can also be synthesized by the body or artificially developed in laboratories.

From Tokyo University of Science 1 Oct 2021

Scientists isolate monoclonal antibodies against alphaviruses

A research group has isolated monoclonal antibodies that, in laboratory and animal studies, prohibited infection by alphaviruses.

From Vanderbilt University 24 Aug 2021

Study identifies variants and genes linked to alcohol consumption

Scientists from the Icahn School of Medicine at Mount Sinai published the first of its kind research in the field of addiction genetics employing a multi-omics method to offer a huge list of causal candidate genes linked with alcohol consumption and alcohol use disorder (AUD).

24 Aug 2021

Restoring cholesterol levels could be a new therapeutic approach for neurodegenerative diseases

Scientists have found that the brain lacks the ability to maintain the cholesterol-rich myelin sheath that insulates neurons when a protein is absent.

From National University of Singapore (NUS) 10 Aug 2021

Study shows astrocytes induce sex differences during brain development

Scientists have found that when brain cells develop, they may find various ways to link with each other based on sex.

21 Jul 2021

Novel gene therapy offers hope to children with genetic, neurodegenerative diseases

Newly devised gene therapy can help children born with AADC, a rare genetic disorder that causes developmental and physical disabilities.

13 Jul 2021

Genetic treatment may provide a new approach to addressing obsessive-compulsive disorder (OCD)

For the first time, scientists have linked distinct patterns of genetic mutations with OCD in humans using genome-wide analysis.

29 Jun 2021

Researchers identify key cells involved in childhood brain cancer

A new study coordinated by the University of Trento could have identified the cell of origin of medulloblastoma—a malignant tumor in children that affects the central nervous system. In this study, scientists have used organoids to replicate the tumor tissue, for the first time.

25 Jun 2021

Central Nervous System News and Research

Glial cells in the heart play critical role in cardiac development and function

Genomic changes in advanced tumors reveal interactions with treatment

Tough protein connects directly with neurons to cause damaging inflammatory reaction in the brain

CHOP-led network aims to unlock the genetic mysteries behind pediatric brain tumors

Monoclonal antibodies mitigate inflammatory consequences of SARS-CoV-2 exposure in macaques

Delta opioid receptor agonists modulate immune responses to ameliorate colonic inflammation

Scientists isolate monoclonal antibodies against alphaviruses

Study identifies variants and genes linked to alcohol consumption

Restoring cholesterol levels could be a new therapeutic approach for neurodegenerative diseases

Study shows astrocytes induce sex differences during brain development

Novel gene therapy offers hope to children with genetic, neurodegenerative diseases

Genetic treatment may provide a new approach to addressing obsessive-compulsive disorder (OCD)

Researchers identify key cells involved in childhood brain cancer

Prevalent protein in the blood plays a vital role in human fertilization, infection resistance

Novel protein interactions aid in the recovery process of brain damage

Study reveals key molecule involved in myelin repair

Metagenomic sequencing helps examine differences in the gut microbiome after injury

Gender difference accounts for major psychiatric disorders

Nutritional supplement may reduce the risk of strokes caused by a rare genetic disorder

Synthetic cannabinoid reduces essential tremors by activating astrocytes

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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