Chromatin News and Research

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SLFN11’s surveillance part in protein homeostasis

On July 25th, 2022, a new study perspective called “SLFN11’s surveillance role in protein homeostasis” was published in Volume 9 of Oncoscience.

8 Aug 2022

Experts develop new single-cell “chromatin atlas” of the human genome

Researchers from the University of Virginia School of Medicine have developed a crucial new tool that provides a better understanding of how genes in particular cells affect the risk of developing heart disease, the world’s leading cause of death.

25 Jul 2022

Researchers get deep insights into the functionality of human genome

Scientists from Weill Cornell Medicine and the New York Genome Center, in partnership with Oxford Nanopore Technologies, have introduced a new method for assessing the three-dimensional structure of the human genome, as well as how the genome folds, on a large scale.

27 Jun 2022

Study reveals how amphioxus model analyze the genesis and vertebrates evolution

The two rounds of whole-genome duplication that occurred throughout the evolution of vertebrates were followed by functional divergence in terms of regulatory circuits as well as gene expression patterns.

27 Jun 2022

Scientists discover proteins that may improve CAR-T cell therapy for solid tumor model

The potential of CAR T-cell therapy for the treatment of solid tumors was unlocked in a preclinical trial by researchers at St. Jude Children’s Research Hospital who discovered a molecular mechanism. The findings were released in the journal Nature.

27 Jun 2022

Origin of chromatin in ancient microbes happened 1–2 billion years ago, study reveals

Nature’s storage solution originally emerged in ancient microbes living on Earth around one and two billion years ago, according to researchers at the Center for Genomic Regulation (CRG).

10 Jun 2022

Researchers conduct a comprehensive survey of the aging epigenome across the chromatin hierarchy

Highly structured chromatin encodes the program of life with only one set of genes in the core of every cell. Since various genes are stimulated at different periods of life while staying silent elsewhere, this is feasible. Some genes from a former life stage are hidden deep within the nuclear perimeter, while others manage to break out.

1 Jun 2022

Study highlights the interaction between single-stranded DNA and the linker histone H1

Human DNA is neatly locked in place around a central disc in the tight quarters of the cell nucleus by H1 linker histone that helps shepherd DNA into the tidy chromatin fibers that make up chromosomes. The linker histone, on the other hand, is much more than a protein clip.

31 May 2022

Specialist assay kits and microplates for cancer research

Porvair Sciences will exhibit its latest assay kits and microplates for cancer and life science research at the American Association for Cancer Research (AACR) meeting in New Orleans, USA from the 8th – 13th April 2022.

From Porvair Sciences Limited 7 Apr 2022

Yale and uOttawa researchers partner to solve a puzzle rooted in the deepest past of evolution

For decades, scientists have been trying to unravel an enduring mystery of structural biology: Why do two otherwise identical protein forms found in everything from plants, amphibians and human beings hang onto a slight variation across the mighty span of evolution?

21 Mar 2022

Salk researchers present novel technology to assist in examining single brain cells

Researchers at the Salk Institute have created a novel genomic technology that enables them to study DNA, RNA, and chromatin from a single cell at the same time.

11 Mar 2022

Reversing the destructive aging process in egg cells to increase fertility in older women

Throughout much of the world, increasing numbers of women are delaying having their first child until they are in their late thirties, and even into their forties.

9 Mar 2022

Researchers discover new fluorescent DNA label, likely to help detect cancer risk

Scientists develop a new fluorescent label that provides a sharper image of how DNA architecture is disturbed in cancer cells.

From University of Pittsburgh 7 Mar 2022

Researchers create a regulatory map of zebrafish genome

The zebrafish is an important model organism for studying things like genetic diseases. A regulatory map of its genome has been successfully created using high-throughput experiments and AI methods, a team led by Uwe Ohler now reports in Cell Genomics and Nature Machine Intelligence.

25 Feb 2022

Recent study reveals the code involved in human gene regulation

The logic that handles gene regulation in human cells has been discovered by a team of researchers at the University of Helsinki.

24 Feb 2022

Study shows how 3D scaffolding of chromosomes is related across carnivore species

Studies comparing animal genomes generally focus on the DNA sequence itself. A new study by researchers at the University of California, Davis shows how the three-dimensional scaffolding of chromosomes is related across several species of carnivores, offering a new approach of "comparative scaffotyping" that could be used to identify related genes across species and place them in context.

From The University of California, Davis 22 Feb 2022

Chromatin News and Research

SLFN11’s surveillance part in protein homeostasis

Experts develop new single-cell “chromatin atlas” of the human genome

Researchers get deep insights into the functionality of human genome

Study reveals how amphioxus model analyze the genesis and vertebrates evolution

Scientists discover proteins that may improve CAR-T cell therapy for solid tumor model

Origin of chromatin in ancient microbes happened 1–2 billion years ago, study reveals

Researchers conduct a comprehensive survey of the aging epigenome across the chromatin hierarchy

Study highlights the interaction between single-stranded DNA and the linker histone H1

Specialist assay kits and microplates for cancer research

Yale and uOttawa researchers partner to solve a puzzle rooted in the deepest past of evolution

Salk researchers present novel technology to assist in examining single brain cells

Reversing the destructive aging process in egg cells to increase fertility in older women

Researchers discover new fluorescent DNA label, likely to help detect cancer risk

Researchers create a regulatory map of zebrafish genome

Recent study reveals the code involved in human gene regulation

Study shows how 3D scaffolding of chromosomes is related across carnivore species

Study findings open new avenues for research into host-directed therapies for TB

Study creates a new wheat mutant with resistance to disease

Identification of a bivalent histone-mark switch essential for angiogenesis

Kras oncogenes use genetic reprogramming to drive tumorigenesis

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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