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Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.

Cells damaged by chronic lung disease favor SARS-CoV-2 entry

Researchers propose that similar to pouring water atop a wellhead prior to pumping, the airway cells of patients suffering from chronic lung diseases are “primed” for infection by the COVID-19 virus.

16 Jul 2021

New method to analyze the genomes of museum specimens

Natural history collections exhibit museum specimens that hold a wealth of underused genetic information because their DNA is poorly preserved.

16 Jul 2021

Study reveals causal gene in autism model mice with copy number variation

A new study has unraveled a causal gene (Necdin, NDN) in autism model mice that exhibit the chromosomal abnormality known as copy number variation.

13 Jul 2021

Researchers identify a novel pathomechanism leading to Usher syndrome

Human Usher syndrome (USH) is the most common form of hereditary deaf-blindness. Sufferers can be deaf from birth, suffer from balance disorders, and eventually lose their eyesight as the disease progresses.

12 Jul 2021

Carrying out CRISPR/Cas9 in Space

In our latest interview, AZoLifeSciences spoke to a team of researchers about their latest research which involved carrying out CRISPR/Cas9 in Space.

8 Jul 2021

Protein's 'silent code' influences cell movement

The protein actin is ubiquitous and essential for life. In mammals, every cell expresses two of its forms, beta-actin and gamma-nonmuscle-actin. Despite having distinct roles, the two forms are nearly identical, sharing 99% of their amino acid sequence.

8 Jul 2021

Making memories necessitates a lot of DNA breakage

The urgency to remember a dangerous experience requires the brain to make a series of potentially dangerous moves: Neurons and other brain cells snap open their DNA in numerous locations--more than previously realized, according to a new study--to provide quick access to genetic instructions for the mechanisms of memory storage.

7 Jul 2021

Researchers uncover cellular mechanisms by which the silencing therapies act in cells

Gene silencing therapies are used to interfere with, or "silence", the expression of genes that are associated with disorders. Now, a team at TMDU has uncovered some of the cellular mechanisms by which the silencing therapies act in cells.

7 Jul 2021

Neurodevelopmental disorders may be caused by a new genetic variation in a single gene

Genetic variations of a neuro-associated gene termed SPTBN1 have been revealed to cause a neurodevelopmental disorder, according to researchers.

5 Jul 2021

New machine learning method predicts how genes in particular cells are controlled

Researchers from the University of Illinois Chicago have created software that can aid researchers in identifying gene regulators faster.

2 Jul 2021

New 3Cs multiplex approach enables the study of the effect of genetic changes

Dr Manual Kaulich’s team at Goethe University has developed a new 3Cs multiplex approach that permits the effect of genetic alterations in any two genes to be investigated simultaneously in cell cultures.

25 Jun 2021

New methodology assesses whole-genome sequencing data of SARS-CoV-2 mutations

According to researchers from Harvard T.H. Chan School of Public Health and MIT, the use of genome-wide association studies (GWAS) methodology to assess whole-genome sequencing data of SARS-CoV-2 mutations and COVID-19 mortality data can help identify highly pathogenic variants of the virus that should be flagged for containment.

25 Jun 2021

Researchers create first plant embryo gene expression atlas at the single-cell level

A team of researchers from the GMI has created the first plant embryo gene expression atlas at the single-cell level.

22 Jun 2021

Study reveals how cells “read” synthetic ingredients added to a genetic code

If the genome is considered the recipe for life, then base pairs represent the individual ingredients. DNA is made up of these chemical structures, and every living thing on the planet has just four of them.

21 Jun 2021

Genetically engineering NK cells can target and kill glioblastoma stem cells

Preclinical research from The University of Texas MD Anderson Cancer Center finds that although glioblastoma stem cells (GSCs) can be targeted by natural killer (NK) cells, they are able to evade immune attack by releasing the TFG-β signaling protein, which blocks NK cell activity.

18 Jun 2021