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Researchers develop a simple and effective strategy to synthesize site-specific antibody–drug conjugates

Antibody-drug conjugates, an intricate that covalently links a potent cytotoxin to an antibody, have piqued the interest of researchers as a new bio-therapeutic methodology.

14 Feb 2022

Novel function of anti-HIV-1 antibodies discovered using robust microscopy techniques

Using cutting-edge imaging methods on in vitro virus cells, researchers from the Institut Pasteur, CNRS, VRI, and Université de Paris found a role of anti-HIV-1 antibodies.

From Institut Pasteur 14 Feb 2022

Model system for biofilms studied at the BESSY II

Bacterial biofilms can thrive on almost all types of surfaces: We find them on rocks and plants, on teeth and mucous membranes, but also on contact lenses, medical implants or catheters, in the hoses of the dairy industry or drinking water pipes, where they can pose a serious threat to human health.

1 Feb 2022

Study details how cancer cells hijack the metabolic activity of non-cancer cells

Pancreatic cancer is a unique, elusive, and fatal malignancy, with only approximately a 10% five-year survival rate.

27 Jan 2022

CellDrop automated cell counter awarded platinum seal of quality

The DeNovix CellDrop™ Automated Cell Counter has been awarded the Platinum Seal of Quality by SelectScience.

From DeNovix Inc. 25 Jan 2022

High-speed cell sorter rapidly isolates and quantifies cells with complex cellular phenotypes

Isolating individual cells with complex phenotypes – which is key to understanding how these cells function, including to inform disease – is a technological challenge. Now, overcoming this hurdle, researchers present a high-speed cell sorter that uses fluorescence imaging to enable genome-scale studies of complex phenotypes.

21 Jan 2022

Label-free device enables in-situ tracking of cell development and maturation

The biological intracellular microenvironment is diverse, consisting of several cell compartments and intracellular components.

20 Jan 2022

Researchers discover a key mechanism used by Zika virus to evade cell’s antiviral response

The world knows SARS-CoV-2 intimately now, but there are more than 200 virus species capable of infecting humans and causing disease.

19 Jan 2022

New finding could lead to the development of cell death regulators for cancer therapies

Scientists led by Professor Ana J. Garcia-Saez at the CECAD Cluster of Excellence for Aging Research at the University of Cologne have shown that apoptosis, the programmed cell death, involves a direct physical interplay between the two proteins BAX and DRP1.

17 Jan 2022

Excelitas technologies introduces µPAX-3 Pulsed Xenon Light Source

Excelitas Technologies Corp., a leading industrial technology manufacturer focused on delivering innovative, market-driven photonic solutions, announces the new µPAX-3 Pulsed Xenon Light Source.

From Excelitas Technologies Corp. 12 Jan 2022

Scientists develop molecules for myocardial PET and fluorescence bimodal imaging

Heart disease continues to be a leading cause of mortality and morbidity across the globe. Positron emission tomography (PET) has slowly become a remarkable technology of a non-invasive technique for accurately diagnosing cardiac diseases.

11 Jan 2022

Experts determine the assembly of proteins with specialized protein needles

Protein assembly is considered to be an essential factor for the development of ordered biological structures, but how about engineering one.

10 Jan 2022

Boosting Confocal Microscopy Through Artificial Intelligence

In this interview, we speak to Dr. Hari Shroff from the National Institute of Biomedical Imaging and Bioengineering about his latest research into confocal microscopy.

From National Institute of Biomedical Imaging and Bioengineering (NIBIB) 20 Dec 2021

Lack of genetic switch results in malformations during embryonic development

A group of researchers identified how a minor disturbance in the activation mechanism of this gene triggers the origin of clubfoot, a common foot malformation.

17 Dec 2021

Study illustrates the concept of cool microscopy

Fluorescence light microscopy has the unique ability to observe cellular processes over a scale that bridges four orders of magnitude. Yet, its application to living cells is fundamentally limited by the very rapid and unceasing movement of molecules that define its living state.

From The Max Planck Institute 14 Dec 2021

Fluorescence News and Research

Researchers develop a simple and effective strategy to synthesize site-specific antibody–drug conjugates

Novel function of anti-HIV-1 antibodies discovered using robust microscopy techniques

Model system for biofilms studied at the BESSY II

Study details how cancer cells hijack the metabolic activity of non-cancer cells

CellDrop automated cell counter awarded platinum seal of quality

High-speed cell sorter rapidly isolates and quantifies cells with complex cellular phenotypes

Label-free device enables in-situ tracking of cell development and maturation

Researchers discover a key mechanism used by Zika virus to evade cell’s antiviral response

New finding could lead to the development of cell death regulators for cancer therapies

Excelitas technologies introduces µPAX-3 Pulsed Xenon Light Source

Scientists develop molecules for myocardial PET and fluorescence bimodal imaging

Experts determine the assembly of proteins with specialized protein needles

Boosting Confocal Microscopy Through Artificial Intelligence

Lack of genetic switch results in malformations during embryonic development

Study illustrates the concept of cool microscopy

Detachable head-mounted photoacoustic microscope images brain activity in mice

Metrion Biosciences expands ion channel drug discovery service capabilities and in-house expertise

Live-cell probes enable visualization of the elongation phase of transcription

Announcing the Winners of The Scientist’s Top 10 Innovations of 2021

Creating a Biological Clock in a Test Tube

Fluorescence eBook

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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