Metabolites News and Research

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Synthetic food additive causes detrimental effects on the gut microbiota

New clinical research indicates that a widely used food additive, carboxymethylcellulose, alters the intestinal environment of healthy persons, perturbing levels of beneficial bacteria and nutrients.

1 Dec 2021

Research identifies distinct gut bacterial profile highly responsive to IBS dietary therapy

People who respond well to the recommended dietary therapy of restricting intake of fermentable carbs for irritable bowel syndrome, or IBS for short, have an abundance of particular types of bacteria in their gut, reveals research published online in the journal Gut.

23 Nov 2021

Blood metabolite levels altered by coffee consumption and may affect chronic kidney disease risk

Food and beverages may have important effects on kidney health, but the potential biological mechanisms involved are often unclear.

5 Nov 2021

Diet-associated molecules in the gut are linked with aggressive prostate cancer

Cleveland Clinic researchers have shown for the first time that diet-associated molecules in the gut are associated with aggressive prostate cancer, suggesting dietary interventions may help reduce risk. Findings from the study were published in Cancer Epidemiology, Biomarkers & Prevention.

29 Oct 2021

Research reveals new mechanism by which plants can rapidly activate defenses against infections

New work led by Carnegie's Kangmei Zhao and Sue Rhee reveals a new mechanism by which plants are able to rapidly activate defenses against bacterial infections.

27 Oct 2021

Novel method enables quick identification of small active substance molecules

Secondary natural substances that occur in numerous plants, bacteria and fungi can be anti-inflammatory, can ward off pathogens or even prevent the growth of cancer cells. However, making use of the riches provided by nature's medicine cabinet and identifying new natural substances is time-consuming, costly and labour-intensive. A team of bioinformaticians at Friedrich Schiller University Jena has now developed a method that enables much faster and easier identification of small active substance molecules.

18 Oct 2021

Study explores dietary supplementation with vitamin D to support cows’ immune function

Known as a crucial component in the body's ability to absorb and retain calcium, essential to processes such as the development and maintenance of healthy bones, vitamin D has also been found to play important roles in immune defense.

18 Oct 2021

Study details metabolic processes employed by SARS-CoV-2 to attack lung tissue

Scientists from the Karolinska Institutet discovered certain metabolic mechanisms that SARS-CoV-2 employs to attack lung tissue.

13 Oct 2021

Research explains the intricacies of the chemical ecology of seed dispersal

If you're going apple picking this fall, you may find yourself being drawn to the biggest, brightest, and most aromatic apples you can find. Apple trees and other fruit-bearing plants have evolved to produce such appetizing fruit for a reason: to entice people and wild animals to eat their fruit and disperse their seeds.

11 Oct 2021

Findings of a new study likely to help design fluorescent, protein-based sensors

Proteins, the molecular machines, make all living organisms hum. They are capable of healing cells, preventing deadly infections, and more.

4 Oct 2021

Researchers discover underlying metabolic changes that may be pivotal in severe COVID-19

COVID-19 patients have differing immune responses that lead to disease outcomes ranging from asymptomatic SARS-CoV-2 infection to death.

7 Sep 2021

Scientists develop data analysis platform to enhance apple breeding process

A new platform housing data from over 100 apple varieties could shave years off of the breeding process and enable data-driven assessments of how to boost the health benefits of America's favorite fruit.

3 Sep 2021

Novel technique to profile metabolic features using a single isogenic cell sample

A new inexpensive and high-throughput technique for profiling metabolic features using only one isogenic sample of cells has been devised by researchers.

2 Sep 2021

Study shows plants reuse secondary metabolites in primary metabolism

Plant researchers identified that plants are capable of reusing specialized metabolic products and break them down to recover nutrients.

12 Aug 2021

Study shows how single cells take up fatty acids, offering new insights into cancer biology

Researchers have developed a new method that offers novel insights into cancer biology by enabling them to unravel how single cells absorb fatty acids.

21 Jul 2021

Experts evaluate traditional dogmas related to dairy cow health during transition period

For dairy cows, the transition period--the time between a cow giving birth and beginning to produce milk--brings the greatest possibility of health problems.

20 Jul 2021

Metabolite produced by gut microbes found to be involved in regulating commensal bacteria

Researchers at the RIKEN Center for Integrative Medical Sciences (IMS) have discovered that acetate, a major metabolite produced by some intestinal bacteria, is involved in regulating other intestinal bacteria.

20 Jul 2021

Children with rare genetic disorder experience dramatic improvements in a gene therapy trial

Children with a devastating genetic disorder characterized by severe motor disability and developmental delay have experienced sometimes dramatic improvements in a gene therapy trial launched at UCSF Benioff Children's Hospitals.

13 Jul 2021

Study reveals the relationship between gut microbiome and neurodegenerative disorders

Eran Blacher bagged the NOSTER & Science Microbiome Prize 2021 for his work in highlighting the relationship between the microbiome and neurodegenerative diseases.

12 Jul 2021

Meat and meat-based substitutes vary widely in their nutritional content

Plant-based meats are similar to real beef in their taste, along with the 13 nutritional items listed on their labels making them appear equivalent to meat.

8 Jul 2021