Angiotensin News and Research

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Angiotensin is an oligopeptide in the blood that causes vasoconstriction, increased blood pressure, and release of aldosterone from the adrenal cortex. It is a powerful dipsogen. It is derived from the precursor molecule angiotensinogen, a serum globulin produced in the liver. It plays an important role in the renin-angiotensin system.

UNC Charlotte Study: SARS-CoV-2 Variants BA.2.86 and JN.1 Show Minimal Immune Evasion

New research from UNC Charlotte's Center for Computational Intelligence to Predict Health and Environmental Risks (CIPHER) has found that the two recent and prevalent strains of the virus that cause COVID-19, SARS-CoV-2 variants BA.2.86 and JN.1, are not significantly better than their predecessor Omicron at evading immune responses and causing infections despite having a high number of mutations compared to Omicron.

22 Jul 2024

Novel Peptides from South American Bushmaster and Pit Viper

The venom of the South American bushmaster, a resident of tropical rainforests, and the pit viper Cotiara, which lives in southern Brazil, both contain fragments of hemorrhagic toxins that may be used to treat high blood pressure.

8 Jan 2024

Identifying The Best Antibodies Using X-Rays

Imagine you're going to a party where you only know a single person. While you've been friends with this person for a long time, you're concerned about them leaving you alone in a room full of strangers. Even though they promise they'll stick by your side, they immediately walk away from you upon entering the party to speak to someone else they know.

26 Jul 2023

UDCA Use Associated with Reduced Odds of COVID-19

SARS-CoV-2, the virus that causes COVID-19, attaches to a cellular receptor called angiotensin-converting enzyme 2 (ACE2), and activation of the farnesoid X receptor increases ACE2 expression.

6 Apr 2023

New class of oral drugs inhibits a diverse range of SARS-CoV-2 strains

The constant evolution of new COVID-19 variants makes it critical for clinicians to have multiple therapies in their arsenal for treating drug-resistant infections. Researchers have now discovered that a new class of oral drugs that acts directly on human cells can inhibit a diverse range of pathogenic SARS-CoV-2 strains.

13 Mar 2023

Researchers tease apart the molecular components involved in abdominal aneurysms

When the artery that supplies the stomach and the liver forms a bulge that ruptures, this medical emergency results in the deaths of 50 percent of patients before they reach the hospital.

24 Feb 2023

New host protease determinants facilitating the infection of SARS-CoV-2 identified

Researchers from Department of Microbiology, School of Clinical Medicine, LKS Faculty of Medicine, the University of Hong Kong (HKUMed), has identified novel host protease determinants, that facilitate the infection of SARS-CoV-2, including the Omicron variant, which provided new targets for combating the pandemic.

22 Feb 2023

A protein in the lung forms a natural protective barrier against SARS-CoV-2 infection

University of Sydney scientists have discovered a protein in the lung that blocks SARS-CoV-2 infection and forms a natural protective barrier in the human body.

10 Feb 2023

Studying cell membranes’ role in allowing viruses’ spike proteins to infect cells

University of Alberta’s study demonstrates the way cell membranes perform a much bigger role than that was understood in enabling spike proteins on viruses to affect cells.

19 Sep 2022

COVID-19 spike protein caused severe heart damage, new research shows

Heart damage is prevalent in COVID-19 patients, leading many to doubt how the virus impacts the heart.

28 Jul 2022

Scientists discover the first structures of angiotensin-converting enzyme using cryo-EM

University of Cape Town (UCT) researchers have used cryo-electron microscopy to identify the first complete structures of the human angiotensin-converting enzyme (ACE) (cryo-EM). A protein that controls blood pressure, ACE, is essential for maintaining good heart health.

14 Jul 2022

Study pinpoints genes responsible for kidney function

Recently scientists pinpointed 182 genes likely responsible for kidney function—most of which can be targeted with existing drugs.

18 Aug 2021

Study shows a possible link between pesticide exposure and increased COVID-19 susceptibility

Researchers have discovered a possible connection between increased vulnerability to COVID-19 infection and exposure to organophosphate pesticides.

27 Apr 2021

Virus-cell interaction may explain the high infection rate of COVID-19 virus

Bioengineering scientists have now detected a formerly unknown interaction between the spike (or “S”) protein of SARS-CoV-2 and receptors in human cells.

From Lehigh University 29 Mar 2021

Augmented response of immune system explains COVID-19 severity in patients with hypertension

COVID-19 patients who also suffer from high blood pressure are more likely to fall severely ill with the disease, which also leaves them at greater risk of death.

12 Jan 2021

Researchers identify new therapeutic target to fight COVID-19 disease

In COVID-19 patients with severe lung disease, targeting the endothelial cells—that is, cells comprising the blood vessel wall, which control oxygen exchange between the bloodstream and airways—may be an innovative strategy to restore normal function of the lungs.

15 Dec 2020

Angiotensin News and Research

UNC Charlotte Study: SARS-CoV-2 Variants BA.2.86 and JN.1 Show Minimal Immune Evasion

Novel Peptides from South American Bushmaster and Pit Viper

Identifying The Best Antibodies Using X-Rays

UDCA Use Associated with Reduced Odds of COVID-19

New class of oral drugs inhibits a diverse range of SARS-CoV-2 strains

Researchers tease apart the molecular components involved in abdominal aneurysms

New host protease determinants facilitating the infection of SARS-CoV-2 identified

A protein in the lung forms a natural protective barrier against SARS-CoV-2 infection

Studying cell membranes’ role in allowing viruses’ spike proteins to infect cells

COVID-19 spike protein caused severe heart damage, new research shows

Scientists discover the first structures of angiotensin-converting enzyme using cryo-EM

Study pinpoints genes responsible for kidney function

Study shows a possible link between pesticide exposure and increased COVID-19 susceptibility

Virus-cell interaction may explain the high infection rate of COVID-19 virus

Augmented response of immune system explains COVID-19 severity in patients with hypertension

Researchers identify new therapeutic target to fight COVID-19 disease

Molecular markers in the blood can predict severe COVID-19 outcomes

Mutations in SARS-CoV-2 spike protein may improve monoclonal antibody resistance

SARS-Cov-2 spike proteins can directly impact the function of blood-brain barrier

Study shows potential avenues of COVID-19 vulnerability in patients with diabetic kidney disease

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