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Charting a High-Resolution Roadmap for Regeneration of Pancreatic β Cells

At the Shanghai Institute of Nutrition and Health (SINH) of the Chinese Academy of Sciences (CAS), a research group headed by Professor Zhen Shao and the collaborators plotted a high-resolution roadmap for the process of pancreatic β cell regeneration by in vivo transdifferentiation from adult acinar cells with the help of a single-cell RNA sequencing (scRNA-seq) technology.

31 May 2023

Spaceflight increases the risk of developing cancer and heart disease

A groundbreaking study from the Icahn School of Medicine at Mount Sinai found that astronauts are more likely to experience mutations that could be connected to spaceflight and increase their lifetime risk of acquiring cancer and heart disease.

2 Sep 2022

Mitochondrial DNA plays a crucial role in inflammation, study finds

Mitochondria are generally known as the powerhouse of the cell, however, growing research indicates that they may potentially be involved in inflammation.

8 Aug 2022

CRISPR-Cas9 system could help perform very effective target gene silencing

CRISPR-Cas9's extraordinary ability to modify specific areas of DNA has made it a favorite among gene-editing tools for researchers.

6 Jul 2021

Epigenetic changes drive the fate of a B cell

B cells are the immune cells responsible for creating antibodies, and most B cells produce antibodies in response to a pathogen or a vaccine, providing immunity.

14 May 2021

Scientists reveal health benefits of clonal hematopoiesis in allogeneic transplants

Clonal hematopoiesis (CH) is a recently identified condition in which mutations associated with blood cancers are detected in the blood of some healthy, usually older, individuals who don't have cancer. People with CH, while asymptomatic, have an elevated risk of developing blood cancers and other negative health outcomes, including heart attacks and strokes.

7 Dec 2020