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SGLT-2 Inhibitors May Lower Dementia Risk in Type 2 Diabetes Patients, Study Finds

A study reveals SGLT-2 inhibitors significantly reduce dementia risk in type 2 diabetes patients, with effects strengthening over longer treatment durations.

9 Sep 2024

Beta Cells Alone Can Maintain Glycemic Balance Without Other Pancreatic Cells

Our glycemic balance is based on the ability of the pancreatic beta cells to detect glucose and secrete insulin to maintain our blood sugar levels.

4 Sep 2024

Emerging Treatments and Drug Repositioning for NAFLD and NASH

The current research on drug candidates and molecular targets being clinically tested for the treatment of non-alcoholic steatohepatitis (NASH) and NAFLD.

9 Aug 2024

New AI-Generated Proteins Could Revolutionize Medicine and Beyond

A new study Dec. 18 in Nature reports an AI-driven advance in biotechnology with implications for drug development, disease detection, and environmental monitoring.

19 Dec 2023

Glucose-Sensing Neurons May Play a Role in Regulating Blood Sugar

The body's blood glucose level needs to be maintained in a relatively narrow range. It cannot be too high, as it can lead to diabetes, and it cannot be too low because it can cause fainting or even death.

12 Jul 2023

Glutaminase 2 Plays a Key Role in Glucose Homeostasis

Glutaminase 2 (GLS2) is a master regulator of glutaminolysis. GLS2 converts glutamine to glutamate, thereby playing a role in cellular energy production. GLS2 is abundant in the liver, and is also found in pancreatic β-cells. However, the role of GLS2 in pancreatic islets – in which both ɑ- and β- cells are present – associated with glucose metabolism is currently unknown.

6 Jul 2023

The Association Between Type 2 Diabetes Treatment Response and Genetic Variants

People who are at a high risk of developing type 2 diabetes can be prescribed a variety of medications to decrease blood sugar levels, but it is not always apparent which people would benefit from which treatments the most.

6 Jun 2023

The complex link between pancreatic malformations and the “dark genome”

For the first time, scientists at the Centre for Genomic Regulation (CRG) have discovered a DNA sequence that is essential for pancreatic development and function.

25 Aug 2022

Giving attention to beta cells instead of the immune system could be a chance to prevent type 1 diabetes

Research studying the autoimmune response, in which the immune system kills the insulin-producing pancreatic islet beta cells, is a common topic of type 1 diabetes research.

1 Jul 2022

Pre-meal whey protein microgel improves early insulin response, says study

A recent study has proposed that taking an extremely low-calorie whey protein microgel shot 15 minutes before a meal decreases post-meal blood sugar spikes.

1 Oct 2021

New research indicates the link between diabetes and SARS-CoV-2 viral infection

Recently, researchers explained that infection by certain enteroviruses could possibly activate diabetes.

22 Oct 2020

Chemist Develops Potential Drug To Treat Type 2 Diabetes Without Harsh Side Effects

Professor Dr. Robert P. Doyle has developed a new drug to treat type 2 diabetes in millions of patients who are seeking to better control their blood sugar.

24 Jun 2020

Determining effect of drugs in pancreatic islets through single-cell RNA-seq approach

Scientists have developed a technique to assess the impact of particular drugs in pancreatic tissues by using an advanced single-cell RNA sequencing approach.

12 May 2020

Study offers detailed molecular map of interaction patterns of GPCR and different G protein subtypes

G protein-coupled receptors (GPCRs) have crucial roles to play in cell signal transduction and can be used as vital therapeutic targets for several diseases.

20 Mar 2020