Glucocorticoid News and Research

RSS

Glucocorticoid is a compound that belongs to the family of compounds called corticosteroids (steroids). Glucocorticoids affect metabolism and have anti-inflammatory and immunosuppressive effects. They may be naturally produced (hormones) or synthetic (drugs).

Gut Bacteria Influence Stress Responses Through Circadian Rhythms

A pioneering study has uncovered the vital role that gut microbiota plays in regulating stress responses by interacting with the body's circadian rhythms.

6 Nov 2024

Unveiling the Roots of Deadly Infant Leukemia

Researchers at the Josep Carreras Leukaemia Research Institute have identified the genetic foundation for newborn B-cell Acute Lymphoblastic Leukaemia (B-ALL) glucocorticoid resistance through MLL gene rearrangements.

6 Aug 2024

How Glucocorticoids Quell Inflammation

Cortisone and other related glucocorticoids are extremely effective at curbing excessive immune reactions.

13 Apr 2024

Human Pluripotent Stem Cells Converted into Purified Pituitary Tissue

Human pluripotent stem cells were effectively transformed into purified pituitary cells, which aggregated into hormone-secreting organoids.

9 Jun 2023

Circadian clocks involve primarily in fat cell growth

According to two studies conducted by researchers at Weill Cornell Medicine, the circadian clocks that keep the body and its cells synchronized to the 24-hour day-night cycle are severely disrupted.

9 Aug 2022

Research associates depressive diseases and deformability of blood cells

For the first time, a study conducted by the TU Dresden and the University of Zurich in collaboration with the Max Planck Institute for the Science of Light finds a relationship between depressive disorders and mechanical features of all main blood cell types.

19 Apr 2022

Study discovers link between corticosteroid receptors and hippocampal neuroplasticity, ciliary genes

Chronic stress is a well-known cause for mental health disorders. New research has moved a step forward in understanding how glucocorticoid hormones ('stress hormones') act upon the brain and what their function is.

9 Aug 2021

Tiny population of neurons may play a significant role in depression

A tiny population of neurons known to be important to appetite appear to also have a significant role in depression that results from unpredictable, chronic stress, scientists say.

12 Feb 2021

Genetic predispositions affect the efficacy of COVID-19 drugs

A paper recently uploaded to bioRxiv* aimed to utilize genome-wide CRISPR screening to identify genes involved in modulating the activity of COVID-19 drugs.

29 Oct 2020

Study shows how psychological stress leads to debilitating vessel-clogging episodes

Researchers from the Albert Einstein College of Medicine have demonstrated that chronic psychological stress can result in painful vessel-clogging episodes—a frequent cause of hospitalizations and the most typical complication of sickle-cell disease or SCD.

31 Jul 2020