Metabolic Disorders News and Research

RSS

Advanced Sequencing Uncovers Cause of Rare Mitochondrial Encephalopathy

Mitochondrial diseases are among the most prevalent hereditary metabolic disorders, known to occur in one out every 5000 births.

19 Nov 2024

Human Organoids Provide Insights Into Gut Hormone Release

A collaborative team of researchers from the Hubrecht Institute and Roche’s Institute of Human Biology has formulated strategies to identify the regulators involved in intestinal hormone secretion.

18 Oct 2024

Comprehensive multi-omics approach reveals detailed insights into diabetes mechanisms

In a recent study published in Nature Communications, researchers utilized a comprehensive multi-omics approach, integrating genomic, proteomic, and metabolomic data from a diverse cohort, to uncover detailed molecular interactions and identify distinct diabetes subgroups.

20 Sep 2024

Bifidobacterium in Maternal Gut Found to Alter Fetal Brain Growth

Bifidobacterium breve supplementation in pregnant mice alters fetal brain metabolism, highlighting its role in enhancing gestational health and development.

29 Aug 2024

Breakthrough Compound ZTA-261 Shows Promise for Safer Lipid Disorder Treatment

Scientists at Nagoya University in Japan have made a significant breakthrough in treating lipid disorders.

8 Aug 2024

Revealing the Spatial Dynamics of Sebum Production

Changes in gene expression in sebaceous glands have been spatially mapped for the first time in a collaborative project between Leipzig University's Interdisciplinary Centre for Bioinformatics (IZBI) and the Faculty of Veterinary Medicine.

1 Aug 2024

Study Reveals How Sweet Taste Receptor Regulates Blood Sugar and Insulin

The rich research portfolio of the Monell Chemical Senses Center on sweet taste goes way back: Monell scientists were one of four teams in 2001 that found and described the mammalian sweet taste receptor – TAS1R2-TAS1R3.

20 May 2024

Unveiling the Anti-Inflammatory and Anti-Obesity Potential of Menthol-Derived Esters

Obesity and inflammatory diseases are increasing in prevalence and contribute to the growing burden of lifestyle disorders such as diabetes and hypertension. There is a lack of naturally derived alternatives to tackle these issues

20 May 2024

Strategies to Counter Postnatal Growth Retardation in Piglets

The metabolic basis of postnatal growth retardation (PGR) in piglets is not yet clear, but it is characterized by poor production performance, low feed conversion rate, and a high mortality rate.

4 Mar 2024

Gut Microbial Metabolite Linked to Increased Thrombosis Risk in COVID-19 Patients

A gut microbial metabolite called 2-methylbutyrylcarnitine (2MBC) plays a role in exacerbating thrombosis -- the formation of blood clots – researchers report February 23rd in the journal Cell Metabolism.

26 Feb 2024

A New Tool for Monitoring Neuronal Inhibition

By tracking when distinct subsets of brain cells activate, researchers have understood the complex activity patterns found in both human and animal brains for many years. Knowing how long those neurons stay active and when they turn off again is crucial to understanding the brain and its associated disorders.

24 Jan 2024

Unveiling the Role of Exosomes in Regulating Hepatic Lipid Metabolism

Non-alcoholic fatty liver disease (NAFLD), characterized by an excess accumulation of hepatic lipids, is highly prevalent and can progress to cirrhosis and liver cancer.

12 Dec 2023

SFU-UBC Collaboration Pushes Frontiers of Cellular Biology With AI-Enhanced Super-Resolution Microscopy

In 2014, the Nobel Prize in Chemistry celebrated the breakthroughs in super-resolution microscopy, a technology that allows us to capture highly detailed images of small parts of cells using fluorescent microscopy.

11 Dec 2023

Early Life Host Control Shapes Sea Anemone Microbiome Composition

The microbiome, denoting the harmonious assembly of microorganisms within a host, is essential for the optimal operation of plants and animals, including humans.

21 Nov 2023

New Drug-Like Molecule Enhances Mitophagy, Protects Against Neurodegeneration

Having healthy mitochondria, the organelles that produce energy in all our cells, usually portends a long healthy life whether in humans or in C. elegans, a tiny, short-lived nematode worm often used to study the aging process.

14 Nov 2023

Scientists Uncover New Insights into Cellular Recycling Process

Recycling is just as essential in cells as in our more familiar macroscopic world. Cells continuously generate waste products and accumulate damaged components while performing regular functions.

3 Nov 2023

Living Model of Human Liver Offers Help in Combating Liver Diseases

Fatty liver disease is on the rise worldwide, affecting up to 30% of people in Western countries. In addition to drinking, obesity and diabetes are major risk factors.

3 Oct 2023

A High-Resolution Glimpse into Peroxisomal Processes

Every system has a waste management system. The “peroxisomes” are cell organelles that dispose of toxic substances and lipids in the human body, among other things, and thereby avoid major diseases.

27 Sep 2023

Revealing a Novel Signaling Pathway Fostering Aging-Related Chronic Metabolic Disorders

Korean researchers have unveiled a novel signaling pathway that fosters aging-related chronic metabolic disorders.

4 Aug 2023

New Study Sets the Stage to Help People Maintain Weight Loss After Dieting

Researchers led by McMaster University professor Gregory Steinberg and postdoctoral research fellow Dongdong Wang have uncovered a key mechanism for promoting weight loss and maintaining the burning of calories during dieting.

29 Jun 2023