Biochemistry

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Scientists engineer probiotic yeast to produce beta-carotene in the guts of mice

Researchers have genetically engineered a probiotic yeast to produce beta-carotene in the guts of laboratory mice. The advance demonstrates the utility of work the researchers have done to detail how a suite of genetic engineering tools can be used to modify the yeast.

13 Apr 2021

POSTECH researchers bioengineer a novel drug-delivering adhesive patch platform

Blood vessels deliver nutrients and oxygen to each organ in our body. They are difficult to completely restore to their original conditions once damaged by myocardial infarction or severe ischemic diseases. This is because various angiogenic growth factors must be applied sequentially in order to restore the vascular structure.

13 Apr 2021

Study compares effect of vaping and smoking on cells and DNA

Researchers have compared vape e-liquid samples and their aerosols to combustible cigarette smoke using Toxys’ ToxTracker range of in-vitro assays.

12 Apr 2021

Study shows how nitrate presence controls nodule formation in legumes

Legumes, or plants belonging to the bean family, form nodules on their roots to absorb nitrogen.

12 Apr 2021

New method can improve the drug testing process

When developing a new drug, the first question is, “does it work?” and the second question is, “is it harmful?”

9 Apr 2021

Study explains molecular mechanisms of drug resistance in Mycobacterium tuberculosis

A group of researchers from France, Germany, Belarus, Japan, and Russia and headed by a scientist from Skolkovo Institute of Science and Technology (Skoltech) has discovered how Mycobacterium tuberculosis survives in iron-deficient environments by using rubredoxin B (RubB)—a protein that belongs to the rubredoxin family and plays a significant role in adapting to varying environmental conditions.

9 Apr 2021

Inhibiting a specific protein could increase tumor sensitivity to PARP inhibitors

Researchers at the Francis Crick Institute have found that blocking a specific protein could increase tumor sensitivity to treatment with PARP inhibitors. Their work published in Science , suggests combining treatments could lead to improved therapy for patients with inheritable breast cancers.

9 Apr 2021

Researchers discover new species of bumblebee through genome sequencing

Scientists have discovered a new species of bumblebees while investigating genetic diversity in bumblebees in the Rocky Mountains, United States.

8 Apr 2021

Study finds an amyloid link between melanoma and Parkinson’s disease

Parkinson’s disease is a neurodegenerative disorder and melanoma is a type of skin cancer but on the surface, these disorders do not seem to have much in common.

8 Apr 2021

PNA-based method is a key component of the gene editing toolkit

The Somatic Cell Gene Editing Consortium has given an update on the status of their initiative to design safer techniques to edit the genes of disease-relevant somatic cells.

8 Apr 2021

Researchers discover natural brilliant blue food coloring from red cabbage

A natural brilliant blue coloring has been discovered by an international team of researchers including chemists at the University of California, Davis. The new cyan blue, obtained from red cabbage, could be an alternative to synthetic blue food colorings such as the widely used FD&C Blue No. 1.

From The University of California, Davis 8 Apr 2021

Warped immune cell signaling during bile acid exposure may lead to Crohn’s disease

People with Crohn's disease are typically treated with powerful anti-inflammatory medications that act throughout their body, not just in their digestive tract, creating the potential for unintended, and often serious, side effects.

8 Apr 2021

Researchers upend the models of cancer metabolism

Tumors consume glucose at high rates, but a team of Vanderbilt researchers has discovered that cancer cells themselves are not the culprit, upending models of cancer metabolism that have been developed and refined over the last 100 years.

From Vanderbilt University 8 Apr 2021

Discovery of heat-sensing gene could help crops to cope better with climate change

By 2050 global warming could reduce crop yields by one-third. UC Riverside researchers have identified a gene that could put the genie back in the bottle.

7 Apr 2021

Microfluidic probe sends free radicals on live cells

Is there a way to chemically manipulate small, confined areas on cellular surfaces? Scientists have developed a microfluidic probe to send a flow of free radicals on live cells and track the outcome using fluorescence imaging.

7 Apr 2021

Study demonstrates how DNA-like molecules could have joined to form the origin of life

Nagoya University scientists in Japan have demonstrated how DNA-like molecules could have come together as a precursor to the origins of life.

7 Apr 2021

A new way to transform brewer's spent grain into value-added products

Home brewing enthusiasts and major manufacturers alike experience the same result of the beer-making process: mounds of leftover grain. Once all the flavor has been extracted from barley and other grains, what's left is a protein- and fiber-rich powder that is typically used in cattle feed or put in landfills.

7 Apr 2021

Researchers take a key step toward new drugs and vaccines for combating COVID-19

Scientists have achieved a huge step toward new vaccines and drugs for fighting against COVID-19.

6 Apr 2021

New automated process uses ultrashort peptides to print hydrogel scaffolds

A new automated process prints a peptide-based hydrogel scaffold containing uniformly distributed cells. The scaffolds hold their shapes well and successfully facilitate cell growth that lasts for weeks.

6 Apr 2021

Scientists develop a novel strategy to determine the freshness of beef samples

Scientists at Gwangju Institute of Science and Technology, Korea, combine an inexpensive spectroscopy technique with artificial intelligence to develop a new way of assessing the freshness of beef samples. Their method is remarkably quicker and more cost-effective than conventional approaches while maintaining a relatively high accuracy, paving the way for mass-produced devices to identify spoiled meat both in the industry and at home.

5 Apr 2021

Biochemistry

Scientists engineer probiotic yeast to produce beta-carotene in the guts of mice

POSTECH researchers bioengineer a novel drug-delivering adhesive patch platform

Study compares effect of vaping and smoking on cells and DNA

Study shows how nitrate presence controls nodule formation in legumes

New method can improve the drug testing process

Study explains molecular mechanisms of drug resistance in Mycobacterium tuberculosis

Inhibiting a specific protein could increase tumor sensitivity to PARP inhibitors

Researchers discover new species of bumblebee through genome sequencing

Study finds an amyloid link between melanoma and Parkinson’s disease

PNA-based method is a key component of the gene editing toolkit

Researchers discover natural brilliant blue food coloring from red cabbage

Warped immune cell signaling during bile acid exposure may lead to Crohn’s disease

Researchers upend the models of cancer metabolism

Discovery of heat-sensing gene could help crops to cope better with climate change

Microfluidic probe sends free radicals on live cells

Study demonstrates how DNA-like molecules could have joined to form the origin of life

A new way to transform brewer's spent grain into value-added products

Researchers take a key step toward new drugs and vaccines for combating COVID-19

New automated process uses ultrashort peptides to print hydrogel scaffolds

Scientists develop a novel strategy to determine the freshness of beef samples

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