Biochemistry

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Novel device can help treat type I diabetes mellitus

Type I Diabetes Mellitus, also called T1D, is an autoimmune disorder that results in an irreversible loss of insulin-producing beta-cells found in the pancreas.

2 Apr 2021

New handheld MasSpec Pen can identify meat and fish fraud within seconds

Meat and fish fraud are worldwide issues that cost consumers billions of dollars annually.

1 Apr 2021

Targeting epigenetic mechanisms to advance pharmacological treatments for alcoholism

Abusive alcohol drinking considerably impacts human health. Alcoholism, better defined as Alcohol Use Disorders (AUD), includes a group of pathological entities related to alcohol-induced damage.

1 Apr 2021

Supercomputer simulations help uncover the mechanism for HIV replication

Viruses lurk in the grey area between the living and the nonliving, according to scientists. Like living things, they replicate but they don't do it on their own. The HIV-1 virus, like all viruses, needs to hijack a host cell through infection in order to make copies of itself.

1 Apr 2021

Processed meat associated with an increased risk of cardiovascular disease

Red meat is a major source of medium- and long-chain saturated fatty acids, which may lead to an increased risk of cardiovascular disease. Processed meat, which has been modified to improve taste or extend its shelf-life, has also been associated with an increased risk of cardiovascular disease.

1 Apr 2021

Simple 'designer' pore reproduces selective cellular transport mechanisms

The nucleus is the headquarters of a cell and molecules constantly move across the nuclear membrane through pores. The transport of these molecules is both selective and fast; some 1,000 molecules per second can move in or out.

31 Mar 2021

Plants influence how their bacterial and fungal neighbors react to climate change

University of California, Irvine, biologists have discovered that plants influence how their bacterial and fungal neighbors react to climate change.

31 Mar 2021

Study reveals molecular mechanisms involved in eliminating unwanted cells in the body

Researchers have uncovered molecular mechanisms involved in removing unwanted cells in the body.

29 Mar 2021

Virus-cell interaction may explain the high infection rate of COVID-19 virus

Bioengineering scientists have now detected a formerly unknown interaction between the spike (or “S”) protein of SARS-CoV-2 and receptors in human cells.

From Lehigh University 29 Mar 2021

New technique can measure thousands of proteins in a few minutes

Researchers from Charité - Universitätsmedizin Berlin and the Francis Crick Institute have developed a mass spectrometry-based technique capable of measuring samples containing thousands of proteins within just a few minutes.

26 Mar 2021

Heidelberg team introduces a reproducible division mechanism for synthetic vesicles

One big challenge for the production of synthetic cells is that they must be able to divide to have offspring. In the journal Angewandte Chemie, a team from Heidelberg has now introduced a reproducible division mechanism for synthetic vesicles.

26 Mar 2021

New label-free immune profiling assay to assess rapidly changing host immune response

Researchers from Critical Analytics for Manufacturing Personalized-Medicine (CAMP), an Interdisciplinary Research Group (IRG) at the Singapore-MIT Alliance for Research and Technology (SMART), MIT's research enterprise in Singapore, have developed a new label-free immune profiling assay that profiles the rapidly changing host immune response in case of infection, in a departure from existing methods that focus on detecting the pathogens themselves, which can often be at low levels within a host.

26 Mar 2021

Study reveals how lipids and water molecules control 5-hydroxytryptamine receptors

Serotonin, or 5-hydroxytryptamine (5-HT), is a kind of neurotransmitter. 5-HT can regulate multifaceted physiological functions such as mood, cognition, learning, memory, and emotions through 5-HT receptors.

26 Mar 2021

Toxin in potatoes is a divergent of bitter-tasting compound in tomatoes

A multi-institutional collaboration has revealed that α-solanine, a toxic compound found in potato plants, is a divergent of the bitter-tasting α-tomatine, which is found in tomato plants.

26 Mar 2021

Xylem filters from native trees help purify drinking water

The interiors of nonflowering trees such as pine and ginkgo contain sapwood lined with straw-like conduits known as xylem, which draw water up through a tree's trunk and branches. Xylem conduits are interconnected via thin membranes that act as natural sieves, filtering out bubbles from water and sap.

From Massachusetts Institute of Technology (MIT) 26 Mar 2021

Electron cryo-tomography reveals 3D images of sarcomeres at high resolution

Using electron cryo-tomography, researchers have created the first high-resolution 3D image of the sarcomere.

25 Mar 2021

Nutritional supplement may reduce the risk of strokes caused by a rare genetic disorder

Researchers from Children's Hospital of Philadelphia (CHOP) have discovered that a widely used nutritional supplement may significantly reduce the risk of fatal strokes caused by a rare genetic disorder.

24 Mar 2021

Improved version of CRISPR/Cas9 tool helps study the interaction of various genes

Researchers have used an upgraded version of the gene-editing tool, CRISPR/Cas9, to knock out up to 12 genes in plants in just one go.

23 Mar 2021

Study reveals mechanism by which ibuprofen prevents RAC1B alternative splicing in colorectal cells

Oncotarget published "Ibuprofen disrupts a WNK1/GSK3β/SRPK1 protein complex required for expression of tumor-related splicing variant RAC1B in colorectal cells" which reported that although the molecular mechanism behind the antitumor properties of NSAIDs has been largely attributed to inhibition of cyclooxygenases , several studies have shown that the chemopreventive properties of ibuprofen also involve multiple COX-independent effects.

23 Mar 2021

Study maps structure, mechanism of membrane enzyme that has a role in chronic inflammation, cancer

A majority of the drugs work through the membranes surrounding the cells of the body.

22 Mar 2021

Biochemistry

Novel device can help treat type I diabetes mellitus

New handheld MasSpec Pen can identify meat and fish fraud within seconds

Targeting epigenetic mechanisms to advance pharmacological treatments for alcoholism

Supercomputer simulations help uncover the mechanism for HIV replication

Processed meat associated with an increased risk of cardiovascular disease

Simple 'designer' pore reproduces selective cellular transport mechanisms

Plants influence how their bacterial and fungal neighbors react to climate change

Study reveals molecular mechanisms involved in eliminating unwanted cells in the body

Virus-cell interaction may explain the high infection rate of COVID-19 virus

New technique can measure thousands of proteins in a few minutes

Heidelberg team introduces a reproducible division mechanism for synthetic vesicles

New label-free immune profiling assay to assess rapidly changing host immune response

Study reveals how lipids and water molecules control 5-hydroxytryptamine receptors

Toxin in potatoes is a divergent of bitter-tasting compound in tomatoes

Xylem filters from native trees help purify drinking water

Electron cryo-tomography reveals 3D images of sarcomeres at high resolution

Nutritional supplement may reduce the risk of strokes caused by a rare genetic disorder

Improved version of CRISPR/Cas9 tool helps study the interaction of various genes

Study reveals mechanism by which ibuprofen prevents RAC1B alternative splicing in colorectal cells

Study maps structure, mechanism of membrane enzyme that has a role in chronic inflammation, cancer

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