Cell Biology

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Immune system–related differences in dialysis, kidney transplant patients are amplified by SARS-CoV-2

People with kidney failure who are on dialysis or who have received a kidney transplant face a higher risk of dying from COVID-19.

8 Nov 2021

Researchers investigate how brain's immune cells relate to a gene mutation in Alzheimer's disease

When immune cells move throughout the brain, they act as the first line of defense against viruses, toxic materials and damaged neurons, rushing over to clear out them.

8 Nov 2021

'Rewiring' the mitochondria in macrophages can resolve inflammatory reactions

New data from a research team at Friedrich-Alexander-Universität Erlangen-Nürnberg shows how inflammatory reactions can be resolved by changes to the metabolism of macrophages.

8 Nov 2021

Formation of transcription factories in living cells resembles the condensation of liquids

It is essential for cells to control precisely which of the many genes of their genetic material they use. This is done in so-called transcription factories, molecular clusters in the nucleus.

5 Nov 2021

Earlier known protein complex acts as a centriole stabilizer, says study

Microtubules are fibers in cells that construct a network to offer shape and structure to cells along with mediating transport mechanisms.

4 Nov 2021

Research reveals pathways controlling osteocyte development

Osteocytes are seen within bone tissue. They are cells with tree-like projections known as dendrites vital for receiving communication from other cells.

4 Nov 2021

Research uncovers key component of cellular malfunction that contributes to tumor growth

Scientists have homed in on a crucial step within the sequence of chemical reactions that govern regulation of cell division, proliferation and death, and whose malfunction contributes to the growth of tumors.

3 Nov 2021

Novel lung phantom mimicking pulmonary optical properties may enable air volume assessment

Take a nice, deep breath. Now imagine your lungs: myriad airways like branches, each with tiny alveoli like leaves. This alveolar structure is key to the absorption of oxygen and excretion of carbon dioxide that we call "breath."

2 Nov 2021

Monoclonal antibodies mitigate inflammatory consequences of SARS-CoV-2 exposure in macaques

Monoclonal antibodies protected aged, diabetic rhesus macaque monkeys from disease due to SARS-CoV-2 and reduced signs of inflammation, including in cerebrospinal fluid, according to a new study from researchers at the University of California, Davis.

From The University of California, Davis 2 Nov 2021

Research reveals how foodborne infections protect the gut's nervous system

A simple stomach bug could do a lot of damage. There are 100 million neurons scattered along the gastrointestinal tract-;directly in the line of fire-;that can be stamped out by gut infections, potentially leading to long-term GI disease.

1 Nov 2021

Study reveals what causes T cells to be non-responsive to immunotherapy

Non-small cell lung cancer is the most common type of lung cancer in humans. Some patients with NSCLC receive a therapy called immune checkpoint blockade (ICB) that helps kill cancer cells by reinvigorating a subset of immune cells called T cells, which are "exhausted" and have stopped working.

1 Nov 2021

OHSU part of new project investigating stem cell therapy as potential glaucoma treatment

Oregon Health & Science University is part of a national research project investigating stem cell therapy as a potential treatment for glaucoma, the world's second leading cause of blindness.

1 Nov 2021

SARS-CoV-2 virus may be able to infect the inner ear, study shows

Many Covid-19 patients have reported symptoms affecting the ears, including hearing loss and tinnitus. Dizziness and balance problems can also occur, suggesting that the SARS-CoV-2 virus may be able to infect the inner ear.

1 Nov 2021

Key networks controlling pluripotency and apoptosis during development revealed

During the early stages of human embryonic development, a small collection of cells called human embryonic stem cells co-ordinates growth and differentiation finally giving rise to highly specialized human tissues.

1 Nov 2021

Study unravels unknown facts about SARS-CoV-2 infection

Around 3%–10% of the individuals infected by the SARS-CoV-2 experience moderate to severe disease.

1 Nov 2021

Immune cell patterns can help predict kidney cancer patients' response to immunotherapy

Researchers at the Francis Crick Institute, The Royal Marsden NHS Foundation Trust and UCL have found immune cell patterns within tumors that can help predict if patients with kidney cancer will respond to immunotherapy.

29 Oct 2021

Discovery of long-lived mitochondrial proteins reveals increased stability of the electron transport chain

Mitochondria are known as the powerhouses of the cell, generating the energy that's needed to fuel the functions that our cells carry out.

29 Oct 2021

Cancer cells change their shape and migration modes more often, says research

Recent research from the Oregon State University shows how malignant cells change their shape and migration techniques to attack various tissues.

29 Oct 2021

Study sheds light on the regulation of epigenetic modifications during the development

The hereditary material, DNA, interacts with proteins present in the cell nuclei and forms a tightly packed complex with proteins called “chromatin”.

29 Oct 2021

Study provides novel insights into how cells move through the body

Recent research published in eLife revealed that cells can control their capability to migrate throughout the body with the help of a protein named fascin.

29 Oct 2021

Cell Biology

Immune system–related differences in dialysis, kidney transplant patients are amplified by SARS-CoV-2

Researchers investigate how brain's immune cells relate to a gene mutation in Alzheimer's disease

'Rewiring' the mitochondria in macrophages can resolve inflammatory reactions

Formation of transcription factories in living cells resembles the condensation of liquids

Earlier known protein complex acts as a centriole stabilizer, says study

Research reveals pathways controlling osteocyte development

Research uncovers key component of cellular malfunction that contributes to tumor growth

Novel lung phantom mimicking pulmonary optical properties may enable air volume assessment

Monoclonal antibodies mitigate inflammatory consequences of SARS-CoV-2 exposure in macaques

Research reveals how foodborne infections protect the gut's nervous system

Study reveals what causes T cells to be non-responsive to immunotherapy

OHSU part of new project investigating stem cell therapy as potential glaucoma treatment

SARS-CoV-2 virus may be able to infect the inner ear, study shows

Key networks controlling pluripotency and apoptosis during development revealed

Study unravels unknown facts about SARS-CoV-2 infection

Immune cell patterns can help predict kidney cancer patients' response to immunotherapy

Discovery of long-lived mitochondrial proteins reveals increased stability of the electron transport chain

Cancer cells change their shape and migration modes more often, says research

Study sheds light on the regulation of epigenetic modifications during the development

Study provides novel insights into how cells move through the body

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