Cell Biology

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Study shows how the release of T-cell cytokine combined with fatty acid leads to ferroptosis

Researchers at the University of Michigan Rogel Cancer Center found that a cytokine, a category of protein that acts as messengers in the body, and a fatty acid can work together to trigger a type of cell death previously defined by studies with synthetic molecules.

7 Mar 2022

Research points to a common thread linking diverse neurodegenerative diseases

Take a cell-deep tour of a brain afflicted with Alzheimer's disease, and you will find minuscule clumps of protein that seem suspicious. Ever since the 1980s, when neuroscientists began identifying these protein tangles, researchers have discovered that other brain diseases have their own tangled-protein signatures.

7 Mar 2022

New technique controls gene activity without altering the DNA sequence of the genome

By combining CRISPR technology with a protein designed with artificial intelligence, it is possible to awaken individual dormant genes by disabling the chemical "off switches" that silence them.

7 Mar 2022

Novel ways to increase SC-beta cell’s survivability and functioning via genetic manipulation

New advancements in the transplantation of stem cell-derived insulin-producing beta cells to cure type 1 diabetes have created substantial curiosity.

7 Mar 2022

CNIC study uncovers a nuclear import mechanism essential for organ growth and development

Scientists at the Centro Nacional de Investigaciones Cardiovasculares have identified a nuclear import mechanism essential for organ growth and development. Manipulation of this mechanism has potential applications in the control of organ growth and organ regeneration.

4 Mar 2022

Study identifies the role of three key molecules in the immune defense against porcine reproductive and respiratory syndrome virus

Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) is one of the most deadly diseases in the swine industry.

4 Mar 2022

Researchers discover unusual exploitation of the human immune system by fungus Candida albicans

During infection, the yeast Candida albicans stimulates the release of tiny RNA fragments, which then stimulate its own growth.

3 Mar 2022

Two distinct classes of stem cells drive treatment resistance in patients with myelodysplastic syndromes

Researchers from The University of Texas MD Anderson Cancer Center discovered that treatment resistance in patients with myelodysplastic syndromes (MDS) is caused by two distinct classes of stem cells and identified possible therapeutic approaches that target these cells.

3 Mar 2022

SARS-CoV-2 spike protein can specifically recognize the terminal sialic acid on sugars

The virus causing the current COVID-19 pandemic is the SARS-CoV-2. Soon after the pandemic outbreak in 2019, the ACE-2 protein, which is present on some of our cells´ surface, was identified as the receptor facilitating host cell viral entry.

3 Mar 2022

Innovative sample preparation method for fast and easy protein analysis

In recent years, proteomics research using mass spectrometry to comprehensively investigate the protein components of biological samples has become very popular.

3 Mar 2022

Simple lab model helps investigate the properties of muscle cells from sIBM patients

A team of researchers at Tohoku University have developed a simple lab-based system for growing human muscle cells that are capable of vigorously contracting.

3 Mar 2022

Protein appears key to the function and survival of brain cells most impacted by glaucoma

A ubiquitous protein called sigma 1 receptor, which is known to protect cells from stress, appears key to the function and survival of the neurons most impacted by glaucoma, scientists report.

2 Mar 2022

Intestinal cell changes are driven by the BMP signaling pathway, study finds

Intestinal cells can change specializations during their lives. The BMP signaling pathway – an important communication mechanism between cells – appears to be the driver of these changes.

2 Mar 2022

Researchers discover how pancreatic cells remodel themselves to reduce the immune response in patients at risk for T1D

Scientists have observed for the very first time that insulin-producing cells in the pancreas are attacked by T lymphocytes during the evolution of Type 1 Diabetes.

2 Mar 2022

Researchers design a new imaging approach to accelerate imaging-based research

A new imaging method has been designed and tested by scientists from Johns Hopkins Medicine.

2 Mar 2022

Men and women do have immune cell differences, study says

Researchers at the La Jolla Institute for Immunology have uncovered novel genes associated with the risk of autoimmune disorders in the CD4+ “helper” T cell subset.

2 Mar 2022

Microbes hindering cancer therapy seem to play a bigger role than helpful ones

Melanoma patients receiving therapy that helps their immune system kill cancer cells respond to treatment differently depending on the types of microbes in their gut, and new research suggests the microorganisms hindering therapy have more influence than the beneficial ones.

1 Mar 2022

US research reveals the role of Heparan Sulfate in obesity

AMSBIO reports how researchers at the Washington University School of Medicine (St. Louis, USA) have used their 10E4 Heparan Sulfate (HS) antibody in pioneering obesity research to quantify the role of HS in the process of intercellular mitochondria transfer to macrophages.

From AMS Biotechnology 1 Mar 2022

Looking at protein activity gives a complete picture of leukemia's weaknesses

Blocking a protein chain reaction makes childhood leukemia cells more sensitive to an existing targeted treatment, a new study shows.

28 Feb 2022

Researchers discover new stem cell population that closely matches existing human stem cells

Reik lab researchers’ recent discovery describes a new subpopulation of human embryonic stem cells that closely match the cells present at the genomic “wake up call” of the 8-cell embryo stage in humans.

28 Feb 2022

Cell Biology

Study shows how the release of T-cell cytokine combined with fatty acid leads to ferroptosis

Research points to a common thread linking diverse neurodegenerative diseases

New technique controls gene activity without altering the DNA sequence of the genome

Novel ways to increase SC-beta cell’s survivability and functioning via genetic manipulation

CNIC study uncovers a nuclear import mechanism essential for organ growth and development

Study identifies the role of three key molecules in the immune defense against porcine reproductive and respiratory syndrome virus

Researchers discover unusual exploitation of the human immune system by fungus Candida albicans

Two distinct classes of stem cells drive treatment resistance in patients with myelodysplastic syndromes

SARS-CoV-2 spike protein can specifically recognize the terminal sialic acid on sugars

Innovative sample preparation method for fast and easy protein analysis

Simple lab model helps investigate the properties of muscle cells from sIBM patients

Protein appears key to the function and survival of brain cells most impacted by glaucoma

Intestinal cell changes are driven by the BMP signaling pathway, study finds

Researchers discover how pancreatic cells remodel themselves to reduce the immune response in patients at risk for T1D

Researchers design a new imaging approach to accelerate imaging-based research

Men and women do have immune cell differences, study says

Microbes hindering cancer therapy seem to play a bigger role than helpful ones

US research reveals the role of Heparan Sulfate in obesity

Looking at protein activity gives a complete picture of leukemia's weaknesses

Researchers discover new stem cell population that closely matches existing human stem cells

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