Cell Biology

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New technology efficiently delivers immune checkpoint inhibitors for treating brain tumors

Multi-institutional researchers have succeeded in efficiently delivering an immune checkpoint inhibitor (ICI) into the mouse brain, confirming its high efficacy and specificity in treating orthotopically transplanted mice with glioblastoma (GBM). The research was published in Nature Biomedical Engineering.

12 Oct 2021

Researchers unravel impacts of protein BRD4 on how DNA folds

Recent research enhances the understanding of certain cancers and complex congenital disorders.

8 Oct 2021

$Mesenchymal stem cells with enhanced fracture healing abilities identified$

Mesenchymal stem cells with enhanced fracture healing abilities identified

Mesenchymal stem cells (MSCs) are anticipated to harbor great potential in the area of regenerative medicine, which aims at restoring damaged tissues.

8 Oct 2021

Loss of mitochondrial respiration alters mechanical properties of the cartilage

A group of researchers headed by Professor Dr Bent Brachvogel, Head of Experimental Neonatology at the Faculty of Medicine and University Hospital Cologne, have identified regulatory mechanisms of tissue organization which were earlier unknown.

8 Oct 2021

Experts describe structure of protein complex vital for proper cell function

Mitochondrial diseases exhibit different symptoms like muscle weakness, severe fatigue, even blindness. Most genetic diseases are the result of mitochondrial defects.

8 Oct 2021

Neuronal variability boosts learning and performance, says research

Scientists from Imperial College London discovered that variation between brain cells might accelerate learning and enhance the functioning of the brain and future AI.

8 Oct 2021

Study explores molecular mechanism behind cell homing

Research reveals how stem cells slow down their rolling inside the circulatory system by developing long tethers that bind to the inner surfaces of blood vessels.

8 Oct 2021

Researchers reconstitute the biological clock to better understand circadian rhythms

Daily cycles in virtually every aspect of our physiology are driven by biological clocks (also called circadian clocks) in our cells.

From University of California Santa Cruz 8 Oct 2021

Using artificial intelligence in biology to unravel how cells defend themselves

Imagine the day when any tissue or organ can be repaired or the replacements personalized to the patient.

8 Oct 2021

Low antibody response against SARS-CoV-2 predicts increased mortality

In a study of patients with COVID-19 being treated in intensive care units, people who mounted only a low antibody response against the SARS-CoV-2 virus faced a higher risk of dying.

7 Oct 2021

New gel enhances immunotherapy's effectiveness in glioblastoma

Pairing a newly developed gel with immunotherapy that was delivered to post-surgical mouse brains with glioblastoma, a highly malignant and deadly cancer, improved the immunotherapy's effectiveness, report researchers from the University of North Carolina Lineberger Comprehensive Cancer Center and colleagues.

7 Oct 2021

Study provides novel insights into the breakdown of carminic acid

Carminic acid (a natural red dye extracted from insects) is extensively used in the cosmetic, pharmaceutical, and food industries globally

7 Oct 2021

Novel mechanism sheds light on embryonic stem cell pluripotency

A group of scientists from Sweden recently pinpointed a cellular mechanism that is vital for the ability of these cells to remain as stem cells.

7 Oct 2021

Researchers reveal how and why cytoquakes occur

Researchers earlier identified that animal cell cytoskeletons rearrange quickly at times, starting an earthquake-like disturbance in the part of the cell.

7 Oct 2021

Active genes do not form clusters and share resources during early development in fruit flies

Active genes do not form clusters and share resources during early development in the fruit fly, according to a new study by New York University and Princeton researchers published in the journal Current Biology.

6 Oct 2021

Common drug to treat cancer reverses Alzheimer’s symptoms in mice

A drug commonly used to treat cancer can restore memory and cognitive function in mice that display symptoms of Alzheimer's disease, new UBC research has found.

6 Oct 2021

Researchers use cryo-electron microscopy to resolve 3D structure of protein nanoparticle

Nanoparticles and nanocages are attractive materials that may be applied in color agents, catalysts, and drug delivery.

6 Oct 2021

Researchers identify the mechanism leading to deafness in Norrie disease

A team of Mass Eye and Ear Scientists led by Albert Edge, PhD, working with research fellow Yushi Hayashi, MD, PhD, has identified the mechanism that can lead to deafness in the rare syndrome, Norrie disease.

6 Oct 2021

New study reveals lung cell roles in guiding the immune system

Lung immunity is essential to combat all pulmonary diseases, including COVID-19, pneumonia, lung cancer, asthma and COPD.

6 Oct 2021

Diagnostic value of SARS-CoV-2 specific T cell immune responses may be limited

Can T-cell tests be used to determine whether people have had COVID-19? Scientists at Uppsala University and Karolinska Institutet have jointly analysed this issue under the aegis of the COMMUNITY study at Danderyd Hospital. Their study is published in the scientific journal PLOS ONE.

5 Oct 2021