Cell Biology

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Cellular environment impacts structure of the nuclear pore complex

Context matters. It's true for many facets of life, including the tiny molecular machines that perform vital functions inside our cells.

From Massachusetts Institute of Technology (MIT) 18 Oct 2021

Novel research reveals a vital but previously unknown role for microglia

University of Virginia School of Medicine researchers have revealed a vital but previously unknown role for immune cells that protect the brain from disease and injury: The cells, known as microglia, also help regulate blood flow and maintain the brain's critical blood vessels.

18 Oct 2021

Researchers develop chimeric exosomes that co-activate immune response and tumor microenvironment

Researchers from the Institute of Process Engineering (IPE) of the Chinese Academy of Sciences have developed macrophage–tumor chimeric exosomes that co-activate the immune response and tumor microenvironment to support cancer immunotherapy.

18 Oct 2021

Brain immune cells take up large amounts of sugar at the beginning of neurodegenerative disease

At the beginning of neurodegenerative disease, the immune cells of the brain – the "microglia" – take up glucose, a sugar molecule, to a much greater extent than hitherto assumed.

18 Oct 2021

Skin regeneration after an injury may be linked with motility of skin stem cells

Although sometimes hard to accept, with aging, many things in our bodies change. One of these is the ability of the skin to regenerate. Old skin is just not as good as young skin at healing wounds. However, the molecular and cellular mechanisms underlying this are largely unknown.

18 Oct 2021

Pioneering gene therapy has long-lasting effects on children with deadly immune disorder

Over a decade ago, UCLA physician-scientists began using a pioneering gene therapy they developed to treat children born with a rare and deadly immune system disorder. They now report that the effects of the therapy appear to be long-lasting, with 90% of patients who received the treatment eight to 11 years ago still disease-free.

18 Oct 2021

Study explores dietary supplementation with vitamin D to support cows’ immune function

Known as a crucial component in the body's ability to absorb and retain calcium, essential to processes such as the development and maintenance of healthy bones, vitamin D has also been found to play important roles in immune defense.

18 Oct 2021

Researchers uncover how killer T cells repeatedly reload their toxic weapons to keep on killing

Cambridge researchers have discovered how T cells – an important component of our immune system – are able keep on killing as they hunt down and kill cancer cells, repeatedly reloading their toxic weapons.

15 Oct 2021

Mutant clones outcompete and eliminate early tumors, mouse study shows

Cells carrying mutations can out compete early tumors in the mouse esophagus, so they never make it into cancers, new research has shown.

15 Oct 2021

Virginia Tech scientists receive $1 million grant to predict the mechanics of living cells

With advances in deep learning, machines are now able to "predict" a variety of aspects about life, including the way people interact on online platforms or the way they behave in physical environments.

15 Oct 2021

Scientists show how skin T cells can damage other organs in stem cell transplant patients

More than 40,000 allogeneic hematopoietic stem cell transplants are carried out worldwide every year, mostly for patients suffering from leukemia or other diseases of the hematopoietic system.

15 Oct 2021

Study identifies DNA mutations that impact metabolism and insulin sensitivity in liver disease patients

For the first time, DNA mutations in liver cells have been identified that impact metabolism and insulin sensitivity in patients with liver disease.

15 Oct 2021

Molecular atlas of small cell lung cancer reveals signatures of metastasis and immunosuppression

Imagine you're about to go on a cross-country trip, stopping at spots along the way to admire local attractions.

15 Oct 2021

Researchers detail novel mechanism on muscle regeneration

Muscle regeneration takes place through a complex mechanism that involves different steps and relies on stem cells.

15 Oct 2021

Researchers use photosynthetic microbes as an oxygen source for nerve cells

Each second, the nerve cells in the brain process numerous signals. And the energy needed to carry out these tasks is mostly generated by aerobic metabolism—the reason why the brain needs a constant supply of oxygen.

15 Oct 2021

Researchers improve understanding of molecular mechanisms underlying stomach’s acid pump

Nagoya University researchers and colleagues have improved understanding of the molecular mechanisms of a key protein that makes the stomach acidic. Their findings, published in the journal Nature Communications, could lead to better drugs for stomach ulcers and shed light on the functions of similar proteins across the human body.

15 Oct 2021

New smart microscope developed for the imaging of biological surfaces

Modern biology relies on our ability to observe living cells using microscopes. The latest advances in optical microscopy allow cellular and sub-cellular imaging within model organisms such as the vinegar fly, zebrafish or mouse.

13 Oct 2021

Study: Sex matters when it comes to susceptibility to infections and other health conditions

A University of Alberta-led study shows that when it comes to susceptibility to infections and other health conditions, sex matters.

13 Oct 2021

Eating mushrooms may benefit a person's mental health, study reveals

Mushrooms have been making headlines due to their many health advantages. Not only do they lower one's risk of cancer and premature death, but new research led by Penn State College of Medicine also reveals that these superfoods may benefit a person's mental health.

From Penn State University 13 Oct 2021

Study explores the effects of epigenetic editing in various tumor settings

Recent research reports that the appropriate functioning of this mechanism is essential for tissue homeostasis and cell fate determination.

13 Oct 2021

Cell Biology

Cellular environment impacts structure of the nuclear pore complex

Novel research reveals a vital but previously unknown role for microglia

Researchers develop chimeric exosomes that co-activate immune response and tumor microenvironment

Brain immune cells take up large amounts of sugar at the beginning of neurodegenerative disease

Skin regeneration after an injury may be linked with motility of skin stem cells

Pioneering gene therapy has long-lasting effects on children with deadly immune disorder

Study explores dietary supplementation with vitamin D to support cows’ immune function

Researchers uncover how killer T cells repeatedly reload their toxic weapons to keep on killing

Mutant clones outcompete and eliminate early tumors, mouse study shows

Virginia Tech scientists receive $1 million grant to predict the mechanics of living cells

Scientists show how skin T cells can damage other organs in stem cell transplant patients

Study identifies DNA mutations that impact metabolism and insulin sensitivity in liver disease patients

Molecular atlas of small cell lung cancer reveals signatures of metastasis and immunosuppression

Researchers detail novel mechanism on muscle regeneration

Researchers use photosynthetic microbes as an oxygen source for nerve cells

Researchers improve understanding of molecular mechanisms underlying stomach’s acid pump

New smart microscope developed for the imaging of biological surfaces

Study: Sex matters when it comes to susceptibility to infections and other health conditions

Eating mushrooms may benefit a person's mental health, study reveals

Study explores the effects of epigenetic editing in various tumor settings

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