Cell Biology

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Study shows how telomeres protect chromosome ends

Telomeres are essentially specialized structures that are located at the end of chromosomes. These structures ensure a healthy cell division.

27 Nov 2020

Researchers identify potential new treatments for blindness

Vision loss associated with inherited genetic disease or aging is predicted to affect as many as 16 million people in the world.

27 Nov 2020

CAR T cells display signs of efficacy against hard-to-treat pediatric cancer in phase 1 trial

A phase 1 trial involving 12 children with relapsed neuroblastoma - a hard-to-treat pediatric cancer - shows that anticancer CAR T cells displayed signs of efficacy against these tumors while avoiding damage to nerve tissue.

26 Nov 2020

Using 3D mapping techniques to unravel mystery of blood stem cells

Princess Margaret scientists have revealed how stem cells are able to generate new blood cells throughout our life by looking at vast, uncharted regions of our genetic material that hold important clues to subtle biological changes in these cells.

26 Nov 2020

Warwick researchers design computational model to enable drug predictions against COVID-19

A computational model of a human lung cell has been used to understand how SARS-CoV-2 draws on human host cell metabolism to reproduce by researchers at the University of Warwick.

From The University of Warwick 26 Nov 2020

Cell survival protein could protect the kidneys from 'bystander' damage during cancer therapy

Australian researchers have identified a protein that could protect the kidneys from 'bystander' damage caused by cancer therapies.

From Walter and Eliza Hall Institute of Medical Research (WEHI) 26 Nov 2020

Study explains why immunotherapy works on certain patients with head and neck cancer

Researchers have found new clues about why certain individuals with head and neck cancer are able to respond to immunotherapy, while others fail to do so.

25 Nov 2020

Hormone that suppresses food intake could help tackle obesity

A hormone that can suppress food intake and increase the feeling of fullness in mice has shown similar results in humans and non-human primates, says a new study published today in eLife.

25 Nov 2020

Novel targeted therapy blocks critical metabolic pathways in cancer cells

Scientists have designed a new targeted therapy, known as POMHEX, which inhibits vital metabolic pathways in tumor cells containing specific genetic defects.

24 Nov 2020

Study shows how drug-like small molecules regulate the activity of ion channels

Researchers have recently discovered how the function of therapeutically relevant ion channels is regulated by drug-like small molecules.

24 Nov 2020

Scientists use new technology to observe DNA defects in children with Fanconi anemia

Scientists have successfully utilized a novel stem cell technology to examine the skin, specific to a group of living patients, in laboratory settings.

24 Nov 2020

Study: Benefits of immunotherapy can be improved by boosting stem cell activity

Immune-system T cells have been reprogrammed into regenerative stem cell-like memory (TSCM) cells that are long-lived, highly active "super immune cells" with strong antitumor activity, according to new research from Georgetown Lombardi Comprehensive Cancer Center.

24 Nov 2020

Architecture of cell nucleus can change gene activity in plants

Scientists from the University of Tokyo have learned how the layout of the cell nucleus can alter the activity of genes found in plants.

23 Nov 2020

Genetic modification in the ‘coat’ of fatal brain virus may allow it to escape antibodies

A genetic modification in the 'coat' of a brain infection-causing virus may allow it to escape antibodies, according to Penn State College of Medicine researchers.

23 Nov 2020

First functional analysis of cytokine IL-15L using rainbow trout

The cytokine family including interleukin-2 and -15 (IL-2 and IL-15) started out in a primitive vertebrate species with three related cytokines IL-2, IL-15, and IL-15-like (IL-15L), all sharing binding capacity for receptor chain IL-15Rα. IL-15L was conserved in fishes, reptiles, and some mammals but lost in humans and mice.

23 Nov 2020

Adipose tissue plays key role in the aggravation of COVID-19

There is growing evidence that adipose tissue plays a key role in the aggravation of COVID-19. One of the theories under investigation is that fat cells (adipocytes) act as a reservoir for SARS-CoV-2 and increase viral load in obese or overweight individuals.

23 Nov 2020

Research sheds light on T cell abnormality in critically ill COVID-19 patients

There is an idea within the coronavirus research field that there is some kind of T cell abnormality in critically ill COVID-19 patients, but specific details have not yet been clarified. To shed light on the problem, a research collaboration based in Kumamoto University (Japan) has performed a genetic analysis of T cells from lung tissue of COVID-19 patients.

23 Nov 2020

Researchers reveal new details of crucial steps involved in the maturation of ribosomes

Ribosomes synthesize all the proteins in cells. Studies mainly done on yeast have revealed much about how ribosomes are put together, but an Ludwig-Maximilians-Universitaet (LMU) in Munich team now reports that ribosome assembly in human cells requires factors that have no counterparts in simpler model organisms.

23 Nov 2020

Biologists unravel how tissue geometry influences cell migration

Cells move constantly throughout our bodies, performing myriad operations critical to tissue development, immune responses, and general wellbeing. This bustle is guided by chemical cues long studied by scientists interested in cellular migration.

23 Nov 2020

New research opens up potential target for treating bone disorders

New research has discovered a cell type that governs the way bones form and maintain themselves, opening up a potential target for future therapies for bone disorders like osteoporosis.

23 Nov 2020

Cell Biology

Study shows how telomeres protect chromosome ends

Researchers identify potential new treatments for blindness

CAR T cells display signs of efficacy against hard-to-treat pediatric cancer in phase 1 trial

Using 3D mapping techniques to unravel mystery of blood stem cells

Warwick researchers design computational model to enable drug predictions against COVID-19

Cell survival protein could protect the kidneys from 'bystander' damage during cancer therapy

Study explains why immunotherapy works on certain patients with head and neck cancer

Hormone that suppresses food intake could help tackle obesity

Novel targeted therapy blocks critical metabolic pathways in cancer cells

Study shows how drug-like small molecules regulate the activity of ion channels

Scientists use new technology to observe DNA defects in children with Fanconi anemia

Study: Benefits of immunotherapy can be improved by boosting stem cell activity

Architecture of cell nucleus can change gene activity in plants

Genetic modification in the ‘coat’ of fatal brain virus may allow it to escape antibodies

First functional analysis of cytokine IL-15L using rainbow trout

Adipose tissue plays key role in the aggravation of COVID-19

Research sheds light on T cell abnormality in critically ill COVID-19 patients

Researchers reveal new details of crucial steps involved in the maturation of ribosomes

Biologists unravel how tissue geometry influences cell migration

New research opens up potential target for treating bone disorders

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