Cell Biology

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Virus-mimicking drugs may overcome immunotherapy resistance in tumors

Researchers at the UCLA Jonsson Comprehensive Cancer Center have found that a drug that activates the body's natural defenses by behaving like a virus may also make certain stealthy melanoma tumors visible to the immune system, allowing them to be better targeted by immunotherapy.

15 Oct 2020

Study offers renewed hope for children suffering from myofibrillar myopathies

Stephen Greenspan and Laura Zah were devastated when they learned their son Alexander had a rare genetic mutation, which causes a deadly neuromuscular disease with no known treatment or cure.

15 Oct 2020

DNA structural changes play key role in the recovery phase after DNA damage

A research team from Cologne has discovered that a change in the DNA structure - more precisely in the chromatin - plays a decisive role in the recovery phase after DNA damage. The key is a double occupation by two methyl groups on the DNA packaging protein histone H3 (H3K4me2).

15 Oct 2020

Novel mechanism restores cell function after DNA damage

Scientists have found that a modification in the DNA structure— specifically in the chromatin—plays a key role in the recovery stage following DNA damage.

15 Oct 2020

Statins can reduce risk of heart attacks and other cardiovascular diseases

According to a study recently published in the eLife journal, cholesterol-lowering drugs, known as statins, may lower cancer risk in humans via a pathway unassociated with cholesterol.

15 Oct 2020

Scientists identify heart cells responsible for repairing damaged heart after infarction

A global study has discovered the heart cells responsible for repairing the damage induced to this vital organ following infarction.

15 Oct 2020

A combinational approach to fight against cancer

In their quest to destroy cancer cells, researchers are turning to combinational therapies more and more. Scientists from Germany and China have now combined a chemotherapeutic and photodynamic approach.

14 Oct 2020

Researchers unravel molecular factors that drive severity of COVID-19

While most COVID-19 cases are asymptomatic or mild, severe complications associated with acute respiratory distress have led to more than one million deaths worldwide in just several months.

14 Oct 2020

Immunotherapy using CAR NKT cells shows promise for treating solid tumors

Natural killer T (NKT) cells, a type of immune cells known for their potent anti-cancer properties in murine tumor models, have been developed into a novel form of immunotherapy to treat patients with cancer.

14 Oct 2020

Dynamic map shows how immune cells fight microbes and remember future infections

Scientists have plotted the activity of an unlimited number of genes in the immune cells of mice over the course of an infection.

14 Oct 2020

New software helps analyze individual cells in virtual reality

New virtual reality software now enables scientists to “walk” inside and examine individual cells.

14 Oct 2020

Treatment using immune system T cells preserves vision of mice with retinoblastoma

A treatment that uses immune system T cells, combined with an immune-boosting drug packaged in an injectable gel, was found to preserve the vision of mice implanted with tissue from a human eye cancer known as retinoblastoma.

13 Oct 2020

New computational biology algorithm may enable more effective cellular therapies

Cellular therapy is a powerful strategy to produce patient-specific, personalised cells to treat many diseases, including heart disease and neurological disorders. But a major challenge for cell therapy applications is keeping cells alive and well in the lab.

13 Oct 2020

VAV1 gene mutations may promote growth of T-cell tumors in laboratory mice

Life is an exquisite orchestration of growth and change, with checks and balances that fine-tune complex entwined interactions, both intrinsic and external.

13 Oct 2020

Researchers discover a new mechanism to regulate nerve impulses

Researchers at Linköping University, Sweden, have discovered a new mechanism by which substances can open a certain type of ion channel and in this way regulate nerve impulses.

13 Oct 2020

Research focuses on understanding production of memory B cells and immune responses

The current COVID-19 climate has made vaccines, antibodies, and immune responses topics of everyday conversation. Now, it isn't just immunologists who want to know how our bodies respond to re-infections months, years, or sometimes decades after an initial immune response.

From Osaka University 13 Oct 2020

Study clarifies role of ERβ in growth and regeneration of skeletal muscle in female mice

Researchers at Kumamoto University, Japan generated mice lacking the estrogen receptor beta (ERβ) gene, both fiber-specific and muscle stem cell-specific, which resulted in abnormalities in the growth and regeneration of skeletal muscle in female mice.

13 Oct 2020

Differences in miRNA expression between sporadic and FAP-associated Desmoid tumors

Volume 11, Issue 26 of Oncotarget reported that in this study the authors studied the differences in mi RNA expression between sporadic and FAP-associated Desmoid tumors using microarray confirmed by quantitative PCR.

13 Oct 2020

Stem cells that promote bone repair can also generate arthritic bone spurs

The same stem cells that heal broken bones can also generate arthritic bone spurs called osteophytes, according to a new study in the Annals of the Rheumatic Diseases.

13 Oct 2020

Dopamine and serotonin found to be involved in perception, cognitive capacities

In first-of-their-kind observations in the human brain, an international team of researchers has revealed two well-known neurochemicals -- dopamine and serotonin -- are at work at sub-second speeds to shape how people perceive the world and take action based on their perception.

13 Oct 2020

Cell Biology

Virus-mimicking drugs may overcome immunotherapy resistance in tumors

Study offers renewed hope for children suffering from myofibrillar myopathies

DNA structural changes play key role in the recovery phase after DNA damage

Novel mechanism restores cell function after DNA damage

Statins can reduce risk of heart attacks and other cardiovascular diseases

Scientists identify heart cells responsible for repairing damaged heart after infarction

A combinational approach to fight against cancer

Researchers unravel molecular factors that drive severity of COVID-19

Immunotherapy using CAR NKT cells shows promise for treating solid tumors

Dynamic map shows how immune cells fight microbes and remember future infections

New software helps analyze individual cells in virtual reality

Treatment using immune system T cells preserves vision of mice with retinoblastoma

New computational biology algorithm may enable more effective cellular therapies

VAV1 gene mutations may promote growth of T-cell tumors in laboratory mice

Researchers discover a new mechanism to regulate nerve impulses

Research focuses on understanding production of memory B cells and immune responses

Study clarifies role of ERβ in growth and regeneration of skeletal muscle in female mice

Differences in miRNA expression between sporadic and FAP-associated Desmoid tumors

Stem cells that promote bone repair can also generate arthritic bone spurs

Dopamine and serotonin found to be involved in perception, cognitive capacities

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