Cell Biology

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Genetic analysis reveals the inhibitory role of NSD2 enzyme in cellular senescence

Using a detailed genetic analysis, a research team from Japan-based Kumamoto University has discovered that the NSD2 enzyme, which controls the actions of several genes, also functions to block the aging of cells.

10 Aug 2020

Early neuron training shows promise for regenerative medicine

When it comes to training neural circuits for tissue engineering or biomedical applications, a new study suggests a key parameter: Train them young.

10 Aug 2020

COVID-19 patients have higher incidence of abnormal liver tests

Researchers at the Yale Liver Center found that patients with COVID-19 presented with abnormal liver tests at much higher rates than suggested by earlier studies.

10 Aug 2020

New method targets hidden HIV viral reservoirs during antiretroviral therapy

Scientists at The Wistar Institute may have discovered a new way of identifying and targeting hidden HIV viral reservoirs during treatment with antiretroviral therapy (ART).

10 Aug 2020

New treatment option can improve outcomes in babies with rare cerebrovascular disorder

Endovascular treatment of vein of Galen aneurysmal malformation (VGAM) in babies with severe pulmonary hypertension can improve chances of survival, according to a study released today at the Society of NeuroInterventional Surgery's (SNIS) 17th Annual Meeting.

10 Aug 2020

Study reveals coronavirus-specific structure that may lead to new antiviral strategies

By visualizing coronavirus replication in an infected host cell, researchers may have answered a long-standing question about how newly synthesized coronavirus components are able to be incorporated into fully infectious viruses.

7 Aug 2020

Study shows how neurons communicate when confronted with stroke

Research led by Nicolas Bazan, MD, PhD, Boyd Professor and Director of the Neuroscience Center of Excellence at LSU Health New Orleans School of Medicine, and Ludmila Belayev, MD, LSU Health New Orleans Professor of Neuroscience, Neurology and Neurosurgery, has unlocked a key fundamental mechanism in the communication between brain cells when confronted with stroke.

7 Aug 2020

4D optical coherence tomography offers insight into embryonic heart development

How a valveless embryonic heart tube pumps blood is a long-standing scientific mystery. Thanks to innovations in light-based technology, fresh insights are now available into the biomechanics of mammalian cardiogenesis-;and in particular, the pumping dynamics of the mammalian tubular embryonic heart.

7 Aug 2020

Granule cells operate as gatekeepers

The hippocampus is a region within the brain that contains many neurons that help us to navigate in space. This leads to the nickname of this area: the GPS of the brain.

7 Aug 2020

Metabolic "switch" may offer clues to increased risk of glucose intolerance in post-menopausal women

Researchers at Tufts University School of Medicine and Tufts Graduate School of Biomedical Sciences have discovered neural mechanisms in mice specific to females that can shift estrogen from playing a protective role in glucose metabolism to one that is disruptive.

7 Aug 2020

Study may point to new therapeutic options for COVID-19

Contrary to what has been generally assumed so far, a severe course of COVID-19 does not solely result in a strong immune reaction - rather, the immune response is caught in a continuous loop of activation and inhibition.

7 Aug 2020

Study: Amyloid-beta alters cholesterol biosynthesis in early stages of Alzheimer’s

Korea Brain Research Institute (headed by Suh Pann-ghill) announced on July 24 the discovery that an increase in amyloid-beta in the brain alters cholesterol biosynthesis, which was found by Dr. Cheon Mookyung of KBRI through RNA-seq analysis data (omics) using AI.

7 Aug 2020

Gut dysbiosis in people with Huntington's disease may offer a potential target for future treatment

A world first clinical study of the gut microbiome in people with Huntington's disease (HD) has found that it is not just a disease of the brain, but also of the body.

7 Aug 2020

Researchers identify receptor responsible for activating energy-burning property of brown fat

The receptor responsible for activating the energy-burning property of brown fat in humans has been identified.

6 Aug 2020

Genes linked to Down syndrome abnormalities may offer protection against solid tumors

Scientists from Stanley Manne Children's Research Institute at Ann & Robert H. Lurie Children's Hospital of Chicago discovered that a set of genes with decreased expression in individuals with Down syndrome may lead to clinical abnormalities in this population, such as poor muscle development and heart valve problems.

6 Aug 2020

Researchers develop new models to study molecular characteristics of lung and pancreatic cancers

Scientists at Huntsman Cancer Institute (HCI) at the University of Utah (U of U) report today the development of new models to study molecular characteristics of tumors of the lung and pancreas.

5 Aug 2020

Scientists explore the role of epigenetic regulator factors in embryonic development

A research team at the Max Planck Institute for Molecular Genetics in Berlin has explored the role of factors in embryonic development that do not alter the sequence of DNA, but only epigenetically modify its "packaging".

5 Aug 2020

New findings help to better understand the genetics of neuropsychiatric disorders

A new study led by NorthShore University HealthSystem (NorthShore) and the University of Chicago took a novel approach to identifying SNPs influencing the risk of neuropsychiatric disorders like schizophrenia, bipolar and major depressive disorder, the institutions announced today.

5 Aug 2020

New method reveals the dynamics of cell development and gene activity

Studies on cellular dynamics are vital to interpret the development of cells and the progression of various diseases.

5 Aug 2020

New study may offer a novel, potential target for treating breast cancer

According to researchers, G-quadruplexes have been demonstrated to play a crucial role in specific types of breast cancer for the first time.

5 Aug 2020

Cell Biology

Genetic analysis reveals the inhibitory role of NSD2 enzyme in cellular senescence

Early neuron training shows promise for regenerative medicine

COVID-19 patients have higher incidence of abnormal liver tests

New method targets hidden HIV viral reservoirs during antiretroviral therapy

New treatment option can improve outcomes in babies with rare cerebrovascular disorder

Study reveals coronavirus-specific structure that may lead to new antiviral strategies

Study shows how neurons communicate when confronted with stroke

4D optical coherence tomography offers insight into embryonic heart development

Granule cells operate as gatekeepers

Metabolic "switch" may offer clues to increased risk of glucose intolerance in post-menopausal women

Study may point to new therapeutic options for COVID-19

Study: Amyloid-beta alters cholesterol biosynthesis in early stages of Alzheimer’s

Gut dysbiosis in people with Huntington's disease may offer a potential target for future treatment

Researchers identify receptor responsible for activating energy-burning property of brown fat

Genes linked to Down syndrome abnormalities may offer protection against solid tumors

Researchers develop new models to study molecular characteristics of lung and pancreatic cancers

Scientists explore the role of epigenetic regulator factors in embryonic development

New findings help to better understand the genetics of neuropsychiatric disorders

New method reveals the dynamics of cell development and gene activity

New study may offer a novel, potential target for treating breast cancer

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