Cell Biology

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Researchers create a new model to study early stage of human development

Researchers from the University of Cambridge have devised a new model to analyze an early stage of human development through human embryonic stem cells.

12 Jun 2020

Excessive degradation of mitochondria causes severe disease in children

Researchers at Karolinska Institutet in Sweden have discovered that excessive degradation of the power plants of our cells plays an important role in the onset of mitochondrial disease in children.

12 Jun 2020

Deleting a key gene to create an immune cell with stronger anti-tumor activity

Using induced pluripotent stem cells (iPSCs) and deleting a key gene, researchers at University of California San Diego School of Medicine have created natural killer cells -- a type of immune cell -- with measurably stronger activity against a form of leukemia, both in vivo and in vitro.

From UC San Diego 12 Jun 2020

Baylor researchers uncover a novel mechanism that triggers cellular immune response

Viruses and other disease-causing microbes influence the type of immune response their hosts will develop against them. In some cases, the predominant response involves antibodies, proteins made by the immune system that specifically recognize parts of the invading microbe and mediate its destruction.

12 Jun 2020

Diversity of plant cell gatekeepers could be key to develop crops with bigger yields

Scientists have shed new light on how the network of gatekeepers that controls the traffic in and out of plant cells works, which researchers believe is key to develop food crops with bigger yields and greater ability to cope with extreme environments.

12 Jun 2020

Lungs' immune cells can be activated more easily than previously thought

A significant site of damage during COVID-19 infection is the lungs. Understanding how the lungs' immune cells are responding to viral infections could help scientists develop a vaccine.

12 Jun 2020

New study may lead to novel treatments for heart and liver diseases

A study that closely analyzed the cardiac health of flies offers new evidence that dysfunction in the liver may result in the deterioration of the heart.

11 Jun 2020

Intron detention is integral to post-transcriptional regulation mechanism

Muscle stem cells are the reserve stem cells found in skeletal muscles. They play a crucial role in muscle repair following damage.

11 Jun 2020

Researchers develop intracellular biopsy to isolate targeted miRNAs from living cells

MicroRNAs, are attracting interest relating to human diseases because variations in the expression of miRNAs are often associated with abnormal functions.

11 Jun 2020

Stress-induced chemoresistance is linked to changes in cellular metabolism

There is a wide range of mechanisms related to chemoresistance, a majority of which are yet to be fully understood.

11 Jun 2020

'Lab-on-a-chip' technology accurately detects early and advanced breast cancer

A scalable "lab-on-a-chip" technology based on inkjet printing methods detected breast cancer in plasma samples from patients with more than 90% accuracy, according to a new study.

11 Jun 2020

Microneedle depots effectively deliver stem cells into damaged tissues

Mesenchymal stem cells are multipotent in that they naturally replenish the cell types that build our bone, cartilage and adipose tissues.

10 Jun 2020

Researchers identify genes involved in the development of malignant brain tumor

Researchers have developed a new approach to identify functional mutations and their impact on genes applicable to the development of malignant brain tumors.

10 Jun 2020

Study reveals the role of Cpeb4 protein involved in bone and joint diseases

Osteoclasts are bone-dissolving cells that are extracted from a type of immune cell referred to as macrophages which are required for the maintenance of bones.

10 Jun 2020

Immune system could be 're-trained' to stop attack of healthy cells, study finds

The body's immune system can be re-wired to prevent it from recognizing its own proteins which, when attacked by the body, can cause autoimmune diseases like multiple sclerosis, a significant new study by UK scientists has found.

10 Jun 2020

Cellular mechanophenotyping may help better understand tumor cells

Our ability to predict who will get cancer, how a patient will respond to treatment, or if a patient will relapse is still quite limited. Despite advances in the detection of genetic mutations and the establishment of risk factors, such as age and genetic variants, it remains a great scientific and medical challenge.

10 Jun 2020

KAUST scientists reveal the genetic metronome within malaria parasites

The parasites responsible for malaria seem to march to their own beat.The mystery behind the molecular basis of how these parasites synch their rhythm in replication to the host's clock-driven rhythms has been solved.

10 Jun 2020

Researchers identify a new subset of cells involved in immune response against hepatitis B

For the first time, researchers at The Westmead Institute for Medical Research have identified and described a new and unique subset of human cells that are involved in the immune response against hepatitis B (HBV) infection. The discovery could help develop new treatments for HBV and inform future vaccine design.

10 Jun 2020

Study shows how a network of genes directs trachea and esophagus development

A new study reporting how a network of genes directs the development of the trachea and oesophagus in mice has been published today in eLife.

10 Jun 2020

Study identifies new pathway to attack tumor cells

A study led by the Institut de Neurociències describes a new strategy to tackle cancer, based on inducing a potent stress in tumor causing cell destruction by autophagy.

10 Jun 2020