Cell Biology

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How do cells react to stressful conditions?

Most often, cells are subjected to stressful conditions that can pose a serious threat to life, for example, toxins or high temperatures.

23 Apr 2020

Scientists find gene signature linked to worst prognosis in rare uterine cancer

Women who don't survive a rare and aggressive uterine cancer called uterine serous carcinoma, have high expression of a group of 73 genes, a score scientists say can help identify these women and improve their outcome.

22 Apr 2020

Study shows how tumor cells respond to nutrient deficiency

Some solid tumors have a very high growth rate, which often leads to a lack of vascularization due to the impossibility to develop, at the same time, the blood vessels that accompany and nourish it.

22 Apr 2020

New study could lead to effective immunotherapy treatments for cancer patients

According to a study recently published in the eLife journal, researchers have devised a new method to chart the molecules present on tumor cells that indicate their presence to the immune system.

22 Apr 2020

A novel prediction method for promising antiviral drug or vaccine targets

A novel method to predict the most promising targets for antiviral drugs or vaccines is based on the conformational changes viral glycoproteins go through during the process of recognition and binding to the host cell.

21 Apr 2020

Discovery marks a critical step toward developing new anti-cancer drugs

A team of scientists led by the University of Michigan Rogel Cancer Center and Case Comprehensive Cancer Center has identified the binding site where drug compounds could activate a key braking mechanism against the runaway growth of many types of cancer.

21 Apr 2020

A ‘virtual embryo’ for unprecedented single-cell studies

Researchers from EMBL Heidelberg and from the University of Padua School of Medicine have created the first complete description of early embryo development, accounting for every single cell in the embryo.

21 Apr 2020

Study reveals the formation of tuft cells and their role in immunity

Chronic pancreatitis, or persistent inflammation of the pancreas, is a known risk factor that leads to the development of pancreatic cancer, which is the third-deadliest cancer in the United States.

20 Apr 2020

Chemical tools can regulate lipid concentration in living cells

Lipids have several crucial functions in the human body: They serve as messengers, which mediate the growth of cells and regulate the release of hormones.

20 Apr 2020

Study shows how human embryonic stem cells commit to early specialization

Scientists at the Francis Crick Institute have identified the point when stem cells in human embryos irreversibly commit to specialization.

20 Apr 2020

Specialized proteins could help combat severe cytokine storms in COVID-19 patients

One of the defining features of COVID-19 is the excessive immune response that can occur in severe cases. This burst of immune overreaction, also called a cytokine storm, damages the lungs and can be fatal.

17 Apr 2020

Newly-discovered mitochondrial small protein is essential for energy production

A newly-discovered small protein in mitochondria is essential for energy production, report Duke-NUS researchers and their colleagues in the journal Nature Communications.

17 Apr 2020

Proving the existence of metabolons

For over four decades, researchers have proposed the presence of enzyme clusters, also called metabolons, which help facilitate several processes within cells.

17 Apr 2020

Mitochondrial protein contributes to degenerative diseases

Scientists and their collaborators from Duke-NUS Medical School (Duke NUS) have recently identified a novel small protein in mitochondria, which is essential for energy production.

17 Apr 2020

Synapses of the human nervous system

The glutamate receptors do not actually adhere to “distance keeping.” Now, high-resolution microscopic studies have revealed that the receptors often appear in small groups at the synapses and remain in contact with other proteins.

17 Apr 2020

Molecular network underlies the structures of critical cellular compartments

Networks are at the heart of everything from communications systems to pandemics. Now researchers have found that a unique type of network also underlies the structures of critical cellular compartments known as membraneless organelles.

16 Apr 2020

Single-cell cloning can lead to new therapies for COPD

Chronic Obstructive Pulmonary Disease (COPD) is a leading cause of death around the world. Now, two internationally acclaimed stem cell experts have discovered a large number of abnormal stem cells found in the lungs of COPD patients.

16 Apr 2020

Improving drug targets for asthma and rheumatoid arthritis

Researchers have found that immune T cells exhibit a range of responsiveness. This finding could offer insights into how the immune system of humans responds to infections and cancer, and what goes wrong in immune diseases.

16 Apr 2020

New method images proteins in 3D with nanoscale resolution

A research team, which also included scientists from the National Synchrotron Light Source II (NSLS-II), has reported a novel method for imaging proteins in three dimensions (3D) with nanoscale resolution.

16 Apr 2020

Novel high-speed microscope successfully records neural activities

Our brain contains tens of billions of nerve cells (neurons) which constantly communicate with each other by sending chemical and electrical flashes, each lasting a short one millisecond (0.001 sec). In every millisecond, these billions of swift-flying flashes altogether traveling in a giant star-map in the brain that lights up a tortuous glittering pattern.

15 Apr 2020