Cell Biology

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AI Program Reveals Cellular Neighborhoods in Cancer Microenvironments

A novel AI-powered program has been developed by researchers at Children's Hospital of Philadelphia (CHOP) to assist in comprehending how various cells arrange themselves into certain tissues and communicate with one another.

9 Jan 2024

Novel Amino Acid Nanoparticles Offer Hope for Fighting Multi-Drug Resistant Cancers

Amino acids, such as tyrosine and tryptophan, are the fundamental building blocks that make up proteins.

9 Jan 2024

Brain's Internal Compass Found to Hold Key to Episodic Memory Formation

Researchers at the University of Tübingen have uncovered new roles for head-direction cells, which may have an impact on the development of episodic memory.

8 Jan 2024

Japanese Scientists Revolutionize Regenerative Lung Medicine

Globally, chronic obstructive pulmonary disease, or COPD, is the third most common cause of mortality. It is characterized by permanent and irreversible lung damage, for which lung transplantation is the only effective treatment. Unfortunately, it is hard to find good lung donors.

8 Jan 2024

Novel Peptides from South American Bushmaster and Pit Viper

The venom of the South American bushmaster, a resident of tropical rainforests, and the pit viper Cotiara, which lives in southern Brazil, both contain fragments of hemorrhagic toxins that may be used to treat high blood pressure.

8 Jan 2024

B12-Producing Gut Bacteria Modulate Neurotransmitter Levels and Reduce Seizures in C. elegans

A new study published in Nature Cell Biology by Mark Alkema, PhD, professor of neurobiology, establishes an important molecular link between specific B12-producing bacteria in the gut of the roundworm C. elegans and the production of acetylcholine, a neurotransmitter important to memory and cognitive function.

5 Jan 2024

Research Reveals Unforeseen Functions for Autophagy Genes in Neuronal Health and Aging

Autophagy, which declines with age, may hold more mysteries than researchers previously suspected. In the January 4th issue of Nature Aging, it was noted that scientists from the Buck Institute, Sanford Burnham Prebys and Rutgers University have uncovered possible novel functions

5 Jan 2024

Scientists Develop Tiny Human Cerebellums to Decipher Disease and Design Therapies

In a first for USC Stem Cell scientists, the laboratory of Giorgia Quadrato, an assistant professor of stem cell biology and regenerative medicine, has pioneered a novel human brain organoid model that generates all the major cell types of the cerebellum, a hindbrain region predominantly made up of two cell types necessary for movement, cognition, and emotion: granule cells and Purkinje neurons.

5 Jan 2024

A Pair of Force-Activated Gene Regulating Proteins Guide Fetal Bone Development

A pair of proteins, YAP and TAZ, has been identified as conductors of bone development in the womb and could provide insight into genetic diseases such as osteogenesis imperfecta, known commonly as "brittle bone disease."

5 Jan 2024

Unraveling the Mysteries of COPII-Mediated Protein Transport

Similar to postal workers who deliver packages in inclement weather, such as snow, rain, or heat waves, a vital set of proteins found in mammals enables cells to operate normally, even in less-than-ideal circumstances.

4 Jan 2024

Zipping Up Chromosomes: The Synaptonemal Complex Revealed

We have two copies of each chromosome in every cell in our bodies except in our reproductive cells. Sperm and egg cells contain a single copy of each chromosome with a unique mix of genes from our parents, an evolutionary trick to give our offspring genetic variability.

4 Jan 2024

Improved Mapping of Small-Molecule Binding Sites in Cells

Researchers at Scripps Research created a novel, high-resolution method for identifying putative treatment targets on proteins in living cells.

3 Jan 2024

Unveiling Cytonemes, the Secret Messengers of the Nervous System

Researchers at St. Jude Children’s Research Hospital captured images of cytonemes, which are cellular projections that are involved in long-distance signal transmission during development.

3 Jan 2024

SPACEL: A Powerful AI Toolkit for Unveiling the 3D Secrets of Tissues

Spatial transcriptomics (ST) technologies are applied in biology and medical research for its ability to detect the spatial distribution of transcriptome in histological tissue slices.

3 Jan 2024

AI Tool Offers a Deep Dive Into Tissues, Boosting Cancer Detection and Treatment

A new artificial intelligence tool that interprets medical images with unprecedented clarity does so in a way that could allow time-strapped clinicians to dedicate their attention to critical aspects of disease diagnosis and image interpretation.

3 Jan 2024

Breakthrough in Synthetic Biology: Researchers Build Artificial CO2-Fixing Pathway

Synthetic biology offers the opportunity to build biochemical pathways for the capture and conversion of carbon dioxide (CO2).

3 Jan 2024

Researchers Identify Key Protein in Maintaining Two Organelles, Thereby Preventing Cellular Aging

Healthy organelles are essential to the operation of the cell, just as healthy organs are essential to human well-being.

2 Jan 2024

Mettl3 Drives Powerful Immune Defense of CD8 T Cells

This study is led by Dr. Shuyang Yu (College of Biological Sciences, China Agricultural University), Dr. Jingyu Xu (The Collaborative Innovation Center of Tissue Damage Repair and Regeneration Medicine of Zunyi Medical University) and Dr. Xuguang Du (College of Biological Sciences, China Agricultural University) and illustrated the key role of Mettl3 in CD8 T cell response during acute infection model.

2 Jan 2024

Study Provides a Systematic View of the Diversity and Function of Supraglacial DNA Viruses

Supraglacial environments mainly consist of four main types of habitats for microbes and viruses, including snow, ice, meltwater, and cryoconites (the granular sediment on glacier surfaces).

2 Jan 2024

The Foundation of Gene Expression in Brain Development

Researchers from Osaka University and Shenzhen Bay Laboratory have uncovered the actions of proteins connected to memory and learning in human brain cells in a study that was just published in Cell Reports.

29 Dec 2023

Cell Biology

AI Program Reveals Cellular Neighborhoods in Cancer Microenvironments

Novel Amino Acid Nanoparticles Offer Hope for Fighting Multi-Drug Resistant Cancers

Brain's Internal Compass Found to Hold Key to Episodic Memory Formation

Japanese Scientists Revolutionize Regenerative Lung Medicine

Novel Peptides from South American Bushmaster and Pit Viper

B12-Producing Gut Bacteria Modulate Neurotransmitter Levels and Reduce Seizures in C. elegans

Research Reveals Unforeseen Functions for Autophagy Genes in Neuronal Health and Aging

Scientists Develop Tiny Human Cerebellums to Decipher Disease and Design Therapies

A Pair of Force-Activated Gene Regulating Proteins Guide Fetal Bone Development

Unraveling the Mysteries of COPII-Mediated Protein Transport

Zipping Up Chromosomes: The Synaptonemal Complex Revealed

Improved Mapping of Small-Molecule Binding Sites in Cells

Unveiling Cytonemes, the Secret Messengers of the Nervous System

SPACEL: A Powerful AI Toolkit for Unveiling the 3D Secrets of Tissues

AI Tool Offers a Deep Dive Into Tissues, Boosting Cancer Detection and Treatment

Breakthrough in Synthetic Biology: Researchers Build Artificial CO2-Fixing Pathway

Researchers Identify Key Protein in Maintaining Two Organelles, Thereby Preventing Cellular Aging

Mettl3 Drives Powerful Immune Defense of CD8 T Cells

Study Provides a Systematic View of the Diversity and Function of Supraglacial DNA Viruses

The Foundation of Gene Expression in Brain Development

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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