Cell Biology

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New Approach Could Power the Development of Advanced Cell Therapies

A new approach to the genetic engineering of cells promises significant improvements in speed, efficiency, and reduction in cellular toxicity compared to current methods.

2 May 2023

How Bacteria Take Action to Break Out of Dormancy

Solving a riddle that has confounded biologists since bacterial spores -; inert, sleeping bacteria -; were first described more than 150 years ago, researchers at Harvard Medical School have discovered a new kind of cellular sensor that allows spores to detect the presence of nutrients in their environment and quickly spring back to life.

2 May 2023

Biological Condensates Harbor Electrical Imbalances That Spark "Redox" Reactions

The human body relies heavily on electrical charges. Lightning-like pulses of energy fly through the brain and nerves and most biological processes depend on electrical ions traveling across the membranes of each cell in our body.

2 May 2023

Occludin Protein Plays a Critical Role in Cell-to-Cell Transmission of SARS-CoV-2 Virus

While the coronavirus continues to infect people around the world, researchers at the University of Missouri have identified a specific protein inside the human body that plays a critical role in how the virus spreads from cell to cell after infection -; a discovery that will help better understand the COVID-19 disease and could lead to the development of new antiviral drugs in the future.

2 May 2023

How Exploratory Actions Enable Animals to Efficiently Learn Their Spatial Environment

Neuroscientists have uncovered how exploratory actions enable animals to learn their spatial environment more efficiently.

2 May 2023

Development of Biocomputing’s Third Approach: Trumpet

Biological computing or biocomputing can revolutionize computers and medicine from early diagnosis and internal cure of diseases to futuristic applications like expanding human memory.

2 May 2023

Demonstrating the Great Potential of Prolamin Scaffolds in Cell-Based Meat Production

The National University of Singapore (NUS) research team has successfully 3D-printed an edible cell culture scaffold using common plant proteins, allowing for more inexpensive and sustainable lab-grown meat to be served on the table.

From National University of Singapore (NUS) 2 May 2023

Previously Unknown Regulatory Mechanism for Circadian and Temperature Signaling Pathways Revealed

Ever wondered why people become tired when the sun goes down? What causes some flower petals to open during the day and close at night? Or how monarch butterflies ascertain when to migrate south?

2 May 2023

Reprogramming the Aging Process to Effectively Promote Longevity

Human lifespan is associated with the aging of individual cells. Three years ago, a group of researchers from the University of California, San Diego, uncovered fundamental mechanisms underlying the aging process.

28 Apr 2023

High-Throughput Screening of Existing Drugs to Fight Multiple Myeloma More Effectively

Multiple myeloma is a rare blood cancer caused by the uncontrolled multiplication of abnormal plasma cells.

28 Apr 2023

Using Synthetic Biology to Reprogram the Cellular Aging Process in Yeast

Engineering a synthetic oscillator that cycles between the two deterioration pathways that lead to cell death can slow aging in yeast cells, increasing their longevity by more than 80%, a new study reports.

28 Apr 2023

High-Throughput Assay to Analyze the Effects of CAR-T Cells Using Image Cytometry

The April 2023 issue of SLAS Discovery contains six full-length articles and one mini-review covering high-throughput screening (HTS) for protease-inhibiting drugs, high-content phenotypic screening and other life sciences research.

28 Apr 2023

Some Promising Human Antibodies can Fight New Variants of SARS-CoV-2

An anonymous San Diego resident has become a fascinating example of how the human immune system fights SARS-CoV-2.

27 Apr 2023

Neuronal Activity Necessary and Sufficient to Drive Astrocyte Development

Researchers at Baylor College of Medicine have unraveled the processes that give astrocytes, the most abundant glial cell in the brain, their special bushy shape, which is fundamental for brain function.

27 Apr 2023

Research Deepens Our Understanding of Circadian Rhythm Regulation

New research from a multidisciplinary team helps to illuminate the mechanisms behind circadian rhythms, offering new hope for dealing with jet lag, insomnia and other sleep disorders.

27 Apr 2023

Highly Tissue-Specific lincRNA Markers Could Indicate the Presence of Disease

Our genetic code includes over 15,000 specific sections that can be made into molecules called lincRNAs.

27 Apr 2023

Getting Insights into Parkinson’s Patients’ Brain Cells Through Stem Cell Research

When the first symptoms of Parkinson’s disease are experienced by a patient, the disease has been evolving for a long period, and the patient might already have lost half of a certain kind of nerve cells in the brain.

27 Apr 2023

Cross-Resistant Bacteria from Agricultural Animal as First Line of Defense in Human

New research headed by the University of Oxford has revealed that overuse of antimicrobials in livestock production can lead to the evolution of bacteria more resistant to the first line of the human immune response. The findings were published today in eLife. They show that farmed chickens and pigs could possess huge reservoirs of cross-resistant bacteria, which are capable of powering future epidemics.

27 Apr 2023

Novel Mathematical Framework Evaluates the Dynamics of Adaptive Immune Evasion

Recent research published in the journal eLife proposes a theory for how cancer cells might actively adapt to the immune system to become resistant to immunotherapy.

27 Apr 2023

Modulation of ERK Signaling Could be Used to Stimulate Regeneration

Why do some animals regenerate lost tissues after injury while others don't? Researchers from the lab of Kerstin Bartscherer (Osnabrück University and formerly Hubrecht Institute) and Ashley Seifert (University of Kentucky) studied spiny mice, which have a remarkable regenerative capacity, to answer this question.

26 Apr 2023

Cell Biology

New Approach Could Power the Development of Advanced Cell Therapies

How Bacteria Take Action to Break Out of Dormancy

Biological Condensates Harbor Electrical Imbalances That Spark "Redox" Reactions

Occludin Protein Plays a Critical Role in Cell-to-Cell Transmission of SARS-CoV-2 Virus

How Exploratory Actions Enable Animals to Efficiently Learn Their Spatial Environment

Development of Biocomputing’s Third Approach: Trumpet

Demonstrating the Great Potential of Prolamin Scaffolds in Cell-Based Meat Production

Previously Unknown Regulatory Mechanism for Circadian and Temperature Signaling Pathways Revealed

Reprogramming the Aging Process to Effectively Promote Longevity

High-Throughput Screening of Existing Drugs to Fight Multiple Myeloma More Effectively

Using Synthetic Biology to Reprogram the Cellular Aging Process in Yeast

High-Throughput Assay to Analyze the Effects of CAR-T Cells Using Image Cytometry

Some Promising Human Antibodies can Fight New Variants of SARS-CoV-2

Neuronal Activity Necessary and Sufficient to Drive Astrocyte Development

Research Deepens Our Understanding of Circadian Rhythm Regulation

Highly Tissue-Specific lincRNA Markers Could Indicate the Presence of Disease

Getting Insights into Parkinson’s Patients’ Brain Cells Through Stem Cell Research

Cross-Resistant Bacteria from Agricultural Animal as First Line of Defense in Human

Novel Mathematical Framework Evaluates the Dynamics of Adaptive Immune Evasion

Modulation of ERK Signaling Could be Used to Stimulate Regeneration

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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