Cell Biology

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New Computational Approach Efficiently Identifies Optimal Genetic Perturbations

A strategy for cellular reprogramming involves using targeted genetic interventions to engineer a cell into a new state.

3 Oct 2023

Wildling Mice With High Microbial Exposure can Develop Allergies

The notion that some level of microbial exposure might reduce our risk of developing allergies has arisen over the last few decades and has been termed the hygiene hypothesis.

3 Oct 2023

New Synthetic Biology Approach Offers Promise for Treating Neurodegenerative Diseases

Researchers at the University of Cologne's CECAD Cluster of Excellence for Aging Research and the CEPLAS Cluster of Excellence for Plant Sciences have found a promising synthetic plant biology approach for the development of a therapy to treat human neurodegenerative diseases, especially Huntington's disease.

3 Oct 2023

Living Model of Human Liver Offers Help in Combating Liver Diseases

Fatty liver disease is on the rise worldwide, affecting up to 30% of people in Western countries. In addition to drinking, obesity and diabetes are major risk factors.

3 Oct 2023

New Insights into the Role of Intrinsically Disordered Regions in Chromatin Biology

According to textbooks, proteins work by folding into stable 3D shapes that, like Lego blocks, precisely fit with other biomolecules.

3 Oct 2023

A High-Resolution Glimpse into Peroxisomal Processes

Every system has a waste management system. The “peroxisomes” are cell organelles that dispose of toxic substances and lipids in the human body, among other things, and thereby avoid major diseases.

27 Sep 2023

Unraveling the Link Between Chromosomal Instability and Cancer Spread

Chromosomal instability is a phenomenon marked by rapid alterations in the count and configuration of chromosomes during cell division. This occurrence is prevalent in solid tumors and is closely associated with the aggressive dissemination of cancer, known as metastasis.

27 Sep 2023

Using Genetic Engineering to Facilitate Mutualistic Relationships Between Plants and Nitrogen-Fixing Microbes

Nitrogen is an essential nutrient for plant growth, but the overuse of synthetic nitrogen fertilizers in agriculture is not sustainable.

27 Sep 2023

How RNA Regulates Gene Silencing Could Pave Way for Novel Cancer Therapies

Deep inside our cells-;each one complete with an identical set of genes-;a molecular machine known as PRC2 plays a critical role in determining which cells become heart cells, versus brain or muscle or skin cells.

27 Sep 2023

Scientists Develop Molecular Radar to Detect Active Cullin-RING Ligases

Our cells have a fleet of 300 molecular machines, called cullin-RING ligases, or "CRLs" for short, that each is capable of triggering destruction of specific proteins for the well-being of our cells.

27 Sep 2023

Ultra-High Field 7 Tesla MRI Helps Better Understand How Light Stimulates the Brain

New research conducted at the University of Liège, using ultra-high field 7 Tesla MRI, provides a better understanding of how light stimulates our brain and could provide new insights into how it works.

25 Sep 2023

Baru Iylwenpeny, the ‘Skilled Hunter’ Crocodile of Central Australia’s Past

A fearsome fossil crocodile that once inhabited Central Australia around 8 million years ago has finally been bestowed with a scientific name.

25 Sep 2023

Novel Imaging Technique Captures Rapid Protein Dynamics

EPFL researchers have created a unique imaging approach for capturing fast protein dynamics.

22 Sep 2023

Breakthrough Method Uncovers MicroRNA Tasks in Single Cells

Scientists at Stockholm University and SciLifeLab have achieved a groundbreaking feat by creating the first technique capable of unveiling the specific functions that microRNAs carry out within individual cells.

22 Sep 2023

New Method That Genetically Modifies Individual Cells in Animals

Researchers at ETH Zurich have created a technique that enables them to genetically alter every animal cell in a unique way.

22 Sep 2023

Bioprinted Neural Networks Mimic Brain Circuitsdani

Researchers from Monash University’s Engineering Department have achieved a significant breakthrough by using “bioinks” that include living nerve cells (neurons) to 3D print nerve networks.

22 Sep 2023

How Scientists are Using iPSCs to Develop New Therapies

In 1998, scientists reported being able to derive cells from human embryos that could develop into almost any cell in the body. In 2007, the field took a huge leap when scientists discovered they could reprogram human adult skin cells to act like these embryonic stem cells.

20 Sep 2023

New Device Mimics Biology to Detect Disease

In living organisms, cells have a very high capacity to process and communicate information by moving molecules or ions through tiny channels that span the cell membrane. UC Santa Cruz Professor of Electrical and Computer Engineering Marco Rolandi's lab and collaborators at MIT have created a device that mimics this biological concept in order to detect disease.

19 Sep 2023

Fruit Fly Study Reveals New Insights into Exercise and Cold Tolerance

As the northern hemisphere experiences shorter and colder days, individuals who prefer morning workouts may encounter increased difficulty in getting up and running.

19 Sep 2023