Cell Biology

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A Nanoplasmonics Approach to Observe Real-Time Production of Cell Secretions

Researchers at the University of Geneva have developed a novel optical imaging approach that provides a four-dimensional view of cell secretions in real-time, including their spatial and temporal dynamics.

13 Apr 2023

Organoid Platform Could Help Reduce the Time for Developing New Conjugate Vaccines

Developing and testing new treatments or vaccines for humans almost always requires animal trials, but these experiments can sometimes take years to complete and can raise ethical concerns about the animals' treatment.

13 Apr 2023

New Technique Identifies a Gene that Drives Clonal Expansion of Abnormal Cells

An international coalition of biomedical researchers co-led by Alexander Bick, MD, PhD, at Vanderbilt University Medical Center has determined a new way to measure the growth rate of precancerous clones of blood stem cells that one day could help doctors lower their patients' risk of blood cancer.

12 Apr 2023

Glycine-Based Tripeptide Treats Severe Form of Fatty Liver Disease in Non-Human Primates

A recently developed amino acid compound successfully treats nonalcoholic fatty liver disease in non-human primates -; bringing scientists one step closer to the first human treatment for the condition that is rapidly increasing around the world, a study suggests.

11 Apr 2023

New Insights on How Developmental Processes Unfold Across the Human Brain

Brain development does not occur uniformly across the brain, but follows a newly identified developmental sequence, according to a new Penn Medicine study.

11 Apr 2023

Autophagy Protein Governs Endometrial Remodeling and Establishment of Pregnancy in Animal Models

Throughout a woman's reproductive life, the endometrium, the mucous membrane lining the uterus, goes through cyclical remodeling. It thickens during the menstrual cycle in preparation for embryo implantation, and it is shed during menstruation when there is no fertilization.

11 Apr 2023

Scientists Illuminate the Mechanism that Raises and Lowers PSMA Expression in Prostate Cancer

Like the better-known prostate-specific antigen (PSA), prostate-specific membrane antigen (PSMA) is a biomarker that can tell physicians much about a patient's metastatic prostate cancer.

11 Apr 2023

A New, Cost-Effective Therapy to Treat a Wide Range of Cancers

A potential immunotherapy method for treating metastatic melanoma is adoptive cell therapy (ACT). The method, which utilizes the use of immune cells extracted from the patient’s own tumors, could offer cancer patients new options for treatment by eschewing radiation therapies and harsh chemotherapy drugs.

11 Apr 2023

Immunotherapy Response in Advanced Melanoma: Effect of Previous Treatments

According to a study conducted by UCLA, patients with advanced melanoma responded differently to PD-1 checkpoint blockade immunotherapy depending on a variety of variables, including whether or not they had previously received CTLA-4 blockade, another type of immunotherapy.

11 Apr 2023

Integrated-Gut-Liver-on-a-Chip can Improve Understanding of Non-Alcoholic Fatty Liver Disease

A new chip that holds different cell types in tiny, interconnected chambers could allow scientists to better understand the physiological and disease interactions between organs.

10 Apr 2023

New Epigenetic Vulnerability Of Acute Myeloid Leukemia Revealed

Acute myeloid leukemia (AML) is an aggressive blood cancer that causes uncontrolled accumulation of white blood cells. Because of the poor outcomes of this disease, researchers across the globe have been on the hunt for new ways to treat AML, while preserving normal blood development.

10 Apr 2023

Retinal Microvasculature may be a Potential Biological Indicator for Predicting Acute Mountain Sickness

This study is led by Dr.Ningli Wang and Dr.Yuan Xie (Beijing Tongren Hospital, Capital Medical University), they provide evidence that retinal microvasculature is a potential biomarker for cerebral microvasculature changes and acute mountain sickness(AMS) development during risk assessment of individuals at high altitudes.

10 Apr 2023

The Modified Development Potential of Worm Embryonic Cells

A startling discovery that challenges the conventional wisdom that the majority of the hereditary information for cell differentiation is encoded within DNA and other genetic factors has been made regarding how specific proteins within the chromosomes of roundworms facilitate their offspring to develop specialized cells generations later.

10 Apr 2023

Study Establishes Two Distinct Regulatory T Cell Populations

According to a recent study headed by the Children’s Hospital of Philadelphia (CHOP), a regulatory class of human T cells is descended from two distinct origins, one related to autoimmunity and one related to protective immunity.

10 Apr 2023

Specialized Diet Stimulates a Unique Form of Programmed Cell Death

Glioblastoma is the most prevalent kind of adult brain tumor.

10 Apr 2023

Trinity Scientists Discover New Mechanisms Involved in Establishing Cellular Identity

A team of scientists led by those in Trinity College Dublin has discovered new mechanisms involved in establishing cellular identity, a process that ensures the billions of different cells in our bodies do the correct job.

10 Apr 2023

New Device Enables Construction of Complex 3D Organoids Without Using Elaborate Techniques

A team led by Masaya Hagiwara of RIKEN national science institute in Japan has developed an ingenious device, using layers of hydrogels in a cube-like structure, that allows researchers to construct complex 3D organoids without using elaborate techniques.

10 Apr 2023

Researchers Identify Antibody that may Block Infection by All Dominant SARS-CoV-2 Variants

A team led by researchers at Weill Cornell Medicine, the University of Wisconsin-Madison; Scripps Research and the University of Chicago has identified an antibody that appears to block infection by all dominant variants of the virus that causes COVID-19, including Omicron, the most recent.

10 Apr 2023

Novel Method can Measure the Abundance and Modification of tRNA Molecules in a Single Step

Ribonucleic acid (RNA) molecules are present in all living cells, with different types of RNA having different jobs.

7 Apr 2023

Key Enzyme in Sugar Metabolism Plays Role in Protecting Cancer Cells

A key enzyme in sugar metabolism is inactivated particularly easily and efficiently by oxidative stress.

7 Apr 2023

Cell Biology

A Nanoplasmonics Approach to Observe Real-Time Production of Cell Secretions

Organoid Platform Could Help Reduce the Time for Developing New Conjugate Vaccines

New Technique Identifies a Gene that Drives Clonal Expansion of Abnormal Cells

Glycine-Based Tripeptide Treats Severe Form of Fatty Liver Disease in Non-Human Primates

New Insights on How Developmental Processes Unfold Across the Human Brain

Autophagy Protein Governs Endometrial Remodeling and Establishment of Pregnancy in Animal Models

Scientists Illuminate the Mechanism that Raises and Lowers PSMA Expression in Prostate Cancer

A New, Cost-Effective Therapy to Treat a Wide Range of Cancers

Immunotherapy Response in Advanced Melanoma: Effect of Previous Treatments

Integrated-Gut-Liver-on-a-Chip can Improve Understanding of Non-Alcoholic Fatty Liver Disease

New Epigenetic Vulnerability Of Acute Myeloid Leukemia Revealed

Retinal Microvasculature may be a Potential Biological Indicator for Predicting Acute Mountain Sickness

The Modified Development Potential of Worm Embryonic Cells

Study Establishes Two Distinct Regulatory T Cell Populations

Specialized Diet Stimulates a Unique Form of Programmed Cell Death

Trinity Scientists Discover New Mechanisms Involved in Establishing Cellular Identity

New Device Enables Construction of Complex 3D Organoids Without Using Elaborate Techniques

Researchers Identify Antibody that may Block Infection by All Dominant SARS-CoV-2 Variants

Novel Method can Measure the Abundance and Modification of tRNA Molecules in a Single Step

Key Enzyme in Sugar Metabolism Plays Role in Protecting Cancer Cells

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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