Genomics

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Increased levels of OAS1 protein may reduce the severity of COVID-19

Increased levels of OAS1 protein may reduce the severity of COVID-19

Researchers at the Lady Davis Institute (LDI) at the Jewish General Hospital have discovered that increased levels of the protein OAS1 are associated with reduced mortality and less severe disease requiring ventilation among patients with COVID-19.

1 Mar 2021

Absence of TRIM37 protein boosts genetic instability in patients with Mulibrey syndrome

Absence of TRIM37 protein boosts genetic instability in patients with Mulibrey syndrome

Researchers from the Andalusian Centre for Molecular Biology and Regenerative Medicine (CABIMER), in collaboration with the Swiss Institute for Experimental Cancer Research (ISREC) have studied the mechanisms behind the higher tendency of people with Mulibrey syndrome to develop tumors.

1 Mar 2021

Two new Alzheimer’s genes discovered

Two new Alzheimer’s genes discovered

AZoLifeSciences speaks to researchers from Tianjin Medical University about their latest research that led to the discovery of two new genes that are linked to Alzheimer's disease.

From Tianjin Medical University 1 Mar 2021

Researchers sequence 64 human genomes at high resolution

Researchers sequence 64 human genomes at high resolution

After the successful conclusion of the “Human Genome Project”, an international research team has sequenced a total of 64 human genomes at high resolution.

26 Feb 2021

Study reveals new functions of ENDOU enzymes

Study reveals new functions of ENDOU enzymes

The majority of organisms feature the series of ENDOU enzymes, but despite this fact, the functions of these enzymes have not been properly understood.

25 Feb 2021

Multidisciplinary approaches for data management in omics research

Multidisciplinary approaches for data management in omics research

Bioinformatics, and by extension omic sciences - the collective disciplines that are dependent on the use of extensive datasets of biological information - present a challenge of data management for researchers all over the world.

25 Feb 2021

Setting new standards for the exchange of human omics data

Setting new standards for the exchange of human omics data

Genomics, transcriptomics, proteomics, metabolomics, and others... The "omics" technologies keep revolutionizing medicine and biomedical sciences.

25 Feb 2021

New method to track how yellow fever mosquito moves through environment

New method to track how yellow fever mosquito moves through environment

The yellow fever mosquito (Aedes aegypti) is the main vector of deadly diseases like dengue fever, chikungunya, and the Zika virus, which result in hundreds of thousands of deaths worldwide each year.

25 Feb 2021

Genes inherited from parents are responsible for severe COVID-19

Genes inherited from parents are responsible for severe COVID-19

For the first time, scientists have discovered the genetic predisposition of severe COVID-19 disease.

24 Feb 2021

DNA origami helps track gene-editing processes

DNA origami helps track gene-editing processes

The genetic scissors, known as CRISPR/Cas9, the finding that received a Nobel Prize in Chemistry, occasionally cut in places that they are not intended to target.

24 Feb 2021

Researchers identify a type of RNA as therapeutic target for Huntington's treatment

Researchers identify a type of RNA as therapeutic target for Huntington's treatment

Huntington's disease is caused by a mutation in the Huntingtin gene (HTT), which appears in adults and features motor, cognitive and psychiatric alterations.

24 Feb 2021

Cre-controlled CRISPR makes conditional gene inactivation more easier

Cre-controlled CRISPR makes conditional gene inactivation more easier

To discover the function of a gene researchers turn it off and observe the consequences. Often genes have multiple functions that differ depending on a tissue and age.

24 Feb 2021

Study provides new information on occurrence of DVL2 gene defect in dogs

Study provides new information on occurrence of DVL2 gene defect in dogs

A recent genetic study at the University of Helsinki provides new information on the occurrence of a DVL2 gene defect associated with a screw tail and its relevance to canine constitution and health.

24 Feb 2021

Interbacterial toxins may contribute to bacterial genetic diversity

Interbacterial toxins may contribute to bacterial genetic diversity

A toxin produced by bacteria as a defense mechanism causes mutations in target bacteria that could help them survive, according to a study published today in eLife.

24 Feb 2021

New gene-editing technique allows for pre-programming of sequential edits

New gene-editing technique allows for pre-programming of sequential edits

Researchers from the University of Illinois Chicago have discovered a new gene-editing technique that allows for the programming of sequential cuts -- or edits -- over time.

24 Feb 2021

Induced pluripotent stem cells show promise to revive wildlife species

Induced pluripotent stem cells show promise to revive wildlife species

A new article shares a significant development in conservation—one that may make the difference between extinction and survival for wildlife species.

23 Feb 2021

Sufficient rest during holidays restores functions associated with DNA regulation

Sufficient rest during holidays restores functions associated with DNA regulation

According to a recent study, sufficient rest during vacation time restored functions linked to DNA regulation in shift workers deprived of sleep.

23 Feb 2021

Environmental DNA can be used to measure genetic diversity of Pacific salmon, trout

Environmental DNA can be used to measure genetic diversity of Pacific salmon, trout

Scientists at Oregon State University and the U.S. Forest Service have demonstrated that DNA extracted from water samples from rivers across Oregon and Northern California can be used to estimate genetic diversity of Pacific salmon and trout.

23 Feb 2021

Study reveals specialized mechanism for translation of mitochondrial genome into proteins

Study reveals specialized mechanism for translation of mitochondrial genome into proteins

An international collaboration among researchers from Finland, Sweden, UK and the USA has captured ribosomes translating messenger RNA expressed from the maternally inherited mitochondrial genome.

23 Feb 2021

Jumping genes are an important force in the creation of new genes during evolution, shows study

Jumping genes are an important force in the creation of new genes during evolution, shows study

In the same way that Lego pieces can be arranged in new ways to build a variety of structures, genetic elements can be mixed and matched to create new genes, according to new research.

23 Feb 2021

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