Genomics

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Study sheds new light on penicillin allergy

Scientists have reported the first strong evidence of the role of HLA-B, a crucial histocompatibility complex gene, in penicillin allergy.

27 Oct 2020

Researchers develop new sensors to detect gene activity

A team of researchers have developed genetic sensors that are capable of detecting the activity of genes, instead of only the genes themselves.

From The University of Warwick 27 Oct 2020

Proviral and antiviral genes may help develop new therapies for COVID-19

Scientists have screened an unlimited number of cells exposed to the COVID-19 virus and detected genes that appear to close the door on the virus.

27 Oct 2020

Anti-inflammatory mediator could play key role in wound healing

"Wound healing is one of the most complex biological processes," writes Professor Kazumitsu Sugiura and Dr Kenta Saito from Fujita Health University, Japan, in their article recently published in Nature's Scientific Reports.

27 Oct 2020

Researchers identify genes associated with autism spectrum disorder

The lack of some genes in the BEC/TCEAL cluster could be related to some alterations associated with the autism spectrum disorder, according to a preclinical study published in the journal Genome Biology, and led by Professor Jordi Garcia Fernàndez, from the Faculty of Biology and the Institute of Biomedicine of the University of Barcelona (IBUB), and researcher Jaime Carvajal, from the Andalusian Centre for Developmental Biology - University Pablo de Olavide (CSIC-UPO).

27 Oct 2020

Study shows potential avenues of COVID-19 vulnerability in patients with diabetic kidney disease

People with diabetes -- especially the 20 to 40 percent with diabetic kidney disease -- are among the most at risk for serious complications and death from COVID-19.

27 Oct 2020

Increased weight is causally protective for breast and prostate cancer

Although a recent campaign by Cancer Research UK emphasized obesity as a risk factor for cancer on par with smoking, the scientific literature on the relationship between increased weight and cancer risk is not so clear.

27 Oct 2020

Researchers identify new potential therapeutic targets for SARS-CoV-2 infection

To identify new potential therapeutic targets for SARS-CoV-2, a team of scientists at the New York Genome Center, New York University, and the Icahn School of Medicine at Mount Sinai, performed a genome-scale, loss-of-function CRISPR screen to systematically knockout all genes in the human genome.

27 Oct 2020

Exploiting CRISPR systems for the fast detection of SARS-CoV-2

A paper published on medRxiv describes a repurposed type III CRISPR-Cas system that can detect the virus from nasopharyngeal swabs in less than an hour.

26 Oct 2020

Researchers propose new way to exploit the weaknesses of cancer cells

Each cell in the human body continuously divides to create new cells. This process occurs without humans’ knowledge.

26 Oct 2020

Study shows how genetic variability may shape mathematical performance in children

According to a study, DNA variation in a gene is linked to early anatomical variations in a region of the brain that plays a crucial role in quantity representation.

26 Oct 2020

Study indicates underlying molecular sources in COVID-19 variability

Humans have different susceptibilities to SARS-CoV-2, and eventually develop varying degrees of fatigue, fever, and breathing problems.

26 Oct 2020

Research demonstrates an agriculturally amenable epigenetic breeding method

Novel grafted plants -- consisting of rootstock epigenetically modified to "believe" it has been under stress -- joined to an unmodified scion, or above-ground shoot, give rise to progeny that are more vigorous, productive and resilient than the parental plants.

23 Oct 2020

Researchers develop "mini lungs" to study SARS-CoV-2 infection

'Mini-lungs' grown from tissue donated to Cambridge hospitals has provided a team of scientists from South Korea and the UK with important insights into how COVID-19 damages the lungs.

23 Oct 2020

Scientists set ambitious goals for biodiversity and sustainability

Nearly three decades have passed since world leaders agreed to reverse biodiversity loss. It hasn't gone according to plan.

23 Oct 2020

Genomic differences can help develop more personalized treatments for African American men

Prostate cancer is the most common type of cancer among American men after skin cancer, but the disease does not affect all races equally.

22 Oct 2020

Study raises ethical concerns about gene-editing technologies

Genome editing of human embryos represents one of the most contentious potential scientific applications today. But what if geneticists could sidestep the controversy by editing sperm and eggs instead?

22 Oct 2020

Ancient embedded elements in human DNA can activate powerful immune response to kill cancer cells

Ancient embedded elements in our DNA from generations past can activate a powerful immune response to kill cancer cells like an infection.

22 Oct 2020

New DNA-cutting tool could advance gene editing for novel treatments

Gene editing for the development of new treatments, and for studying disease as well as normal function in humans and other organisms, may advance more quickly with a new tool for cutting larger pieces of DNA out of a cell's genome, according to a new study by UC San Francisco scientists.

21 Oct 2020