Genomics

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Study detects changes in how diseased neurons sense and use oxygen

Scientists have devised a new method for isolating a kind of brain cell that is related to symptoms of Parkinson’s disease.

17 Nov 2020

Unique experiment shows how corals manage deoxygenation stress

Oxygen is life, in or out of the water, raising concerns that declining ocean oxygen stores are adding an additional environmental stress to already highly vulnerable coral reef ecosystems.

17 Nov 2020

Scientists expand Darwin's evolutionary theory to include "molecular Darwinism"

Darwin's theory of evolution should be expanded to include consideration of a DNA stability "energy code" - so-called "molecular Darwinism" - to further account for the long-term survival of species' characteristics on Earth, according to Rutgers scientists.

From Rutgers University 17 Nov 2020

Light-activated liposomes could help deliver CRISPR gene therapy

Light-activated liposomes could help to deliver CRISPR gene therapy - and the method could prove safer and more direct than current methods.

From The University of New South Wales (UNSW) 16 Nov 2020

New approach can prevent toxicity linked to neurological gene therapy

Scientists have deigned a new method to inhibit a toxicity observed in the sensory neurons of DRG following gene therapy to treat neurological diseases.

12 Nov 2020

Genetically engineered organisms can help mitigate atmospheric carbon

Climate change has become a crucial issue in the world. But in spite of agreements to combat climate change, global temperatures continue to rise.

12 Nov 2020

Researchers identify potential genetic target for treating painful, invasive form of endometriosis

Michigan State University researchers have identified a potential genetic target for treating an especially painful and invasive form of endometriosis.

12 Nov 2020

New data can aid research on disease mutations, preserve endangered species

A large international consortium led by scientists at Uppsala University and the Broad Institute of MIT and Harvard has sequenced the genome of 130 mammals and analyzed the data together with 110 existing genomes to allow scientist to identify which are the important positions in the DNA.

12 Nov 2020

Genetic signature in localized prostate cancer can predict likelihood of tumor metastases

Researchers have identified a genetic signature in localized prostate cancer that can predict whether the cancer is likely to spread, or metastasize, early in the course of the disease and whether it will respond to anti-androgen therapy, a common treatment for advanced disease.

11 Nov 2020

Researchers discover new 'hidden' gene in SARS-CoV-2

Researchers have discovered a new "hidden" gene in SARS-CoV-2--the virus that causes COVID-19--that may have contributed to its unique biology and pandemic potential.

11 Nov 2020

Dietary induction of hepatocyte regeneration could help enhance gene repair in the liver

The thyroid hormone used to promote the proliferation of hepatocytes improved the efficiency of CRISPR/Cas9-mediated gene repair in the mouse liver.

11 Nov 2020

New laboratory test can rapidly detect infectious agents in hospitalized patients

Researchers have designed a laboratory test that can detect the microbial miscreant affecting patients hospitalized with serious infections in just six hours.

11 Nov 2020

Study suggests that melatonin may be a viable treatment option for COVID-19

New findings indicate that melatonin could be a potential treatment option for COVID-19.

10 Nov 2020

Gene-editing technology helps examine heat tolerance of Great Barrier Reef coral

An international research project has used gene-editing technology to examine the heat tolerance of Great Barrier Reef coral with the results set to guide efforts in combatting the effects of climate change.

10 Nov 2020

Tree nut consumption impacts sperm DNA methylation

Many environmental and lifestyle factors have been implicated in the decline of sperm quality, with diet being one of the most plausible factors identified in recent years.

10 Nov 2020

Placental gene expression related to preeclampsia may be affected by vitamin D status

According to the World Health Organization, preeclampsia affects between 2% to 8% of pregnancies. It can cause serious, sometimes fatal, complications in the mother and child.

10 Nov 2020

Obese, pregnant women can reduce infants' health risks through improved diet, physical activity

According to a new study, obese, pregnant women could decrease the health risks of their infants via better diet and increased physical activity.

9 Nov 2020

Unrelated mutations can lead to false positive results in men with advanced prostate cancer

Unrelated mutations, when present in the blood, can lead to false positive results in men with advanced prostate cancer who are undergoing liquid biopsies.

6 Nov 2020

Study provides key insight to better understand the development of Type 2 diabetes

Scientists have found that insulin has met an evolutionary cul-de-sac, limiting its ability to adapt to obesity and thereby rendering most people vulnerable to Type 2 diabetes.

6 Nov 2020

Scientists use genomics to track the outbreak of Yellow fever virus in São Paulo

Yellow fever virus is normally confined to the Amazon region, but the virus circulated in the Southeast of Brazil between 2016 and 2018, causing the worst epidemic and epizootic outbreaks there for decades. The Ministry of Health confirmed 2,251 cases of yellow fever in humans and 1,567 cases in monkeys in Brazil between December 2016 and June 2019.

6 Nov 2020

Genomics

Study detects changes in how diseased neurons sense and use oxygen

Unique experiment shows how corals manage deoxygenation stress

Scientists expand Darwin's evolutionary theory to include "molecular Darwinism"

Light-activated liposomes could help deliver CRISPR gene therapy

New approach can prevent toxicity linked to neurological gene therapy

Genetically engineered organisms can help mitigate atmospheric carbon

Researchers identify potential genetic target for treating painful, invasive form of endometriosis

New data can aid research on disease mutations, preserve endangered species

Genetic signature in localized prostate cancer can predict likelihood of tumor metastases

Researchers discover new 'hidden' gene in SARS-CoV-2

Dietary induction of hepatocyte regeneration could help enhance gene repair in the liver

New laboratory test can rapidly detect infectious agents in hospitalized patients

Study suggests that melatonin may be a viable treatment option for COVID-19

Gene-editing technology helps examine heat tolerance of Great Barrier Reef coral

Tree nut consumption impacts sperm DNA methylation

Placental gene expression related to preeclampsia may be affected by vitamin D status

Obese, pregnant women can reduce infants' health risks through improved diet, physical activity

Unrelated mutations can lead to false positive results in men with advanced prostate cancer

Study provides key insight to better understand the development of Type 2 diabetes

Scientists use genomics to track the outbreak of Yellow fever virus in São Paulo

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