Genomics

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Herpes Gene Therapy Achieves 90% Viral Reduction in Pre-Clinical Studies

Researchers at Fred Hutch Cancer Center have found in pre-clinical studies that an experimental gene therapy for genital and oral herpes removed 90% or more of the infection and suppressed how much virus can be released from an infected individual, which suggests that the therapy would also reduce the spread of the virus.

16 May 2024

Genetic Analysis Sheds Light on the Role of Ribosomal DNA Copy Number in Inflammation and Disease

Ribosomal DNA (rDNA) is present in hundreds of copies in the genome, but has not previously been part of genetic analyses.

16 May 2024

Runt Transcription Factor Links Regeneration and Photosynthesis in Marine Worm-Algae Symbiosis

Many organisms are far more complex than just a single species. Humans, for example, are full of a variety of microbes.

16 May 2024

Discovery of Novel Adrenal Cell Type Linked to Monogamy in Oldfield Mice

What makes the oldfield mouse steadfastly monogamous throughout its life while its closest rodent relatives are promiscuous? The answer may be a previously unknown hormone-generating cell, according to a new study published online today in Nature from scientists at Columbia's Zuckerman Institute.

16 May 2024

Glycosylation and its Role in Human Health and Disease

The current understanding of glycosylation genetics in mammals and the consequences of mutations that impact glycosylation.

16 May 2024

Machine Learning Program Offers Insights Into Promoter Sequences and Transcription

A team led by researchers at UT Southwestern Medical Center developed deep learning models to identify a simple set of rules that govern the activity of promoters – regions of DNA that initiate the process by which genes produce proteins.

15 May 2024

Unlocking the Genetics of Coral-Destroying Crown-of-Thorns Starfish

Scientists are one step closer to combatting coral-destroying crown-of-thorns starfish, following a University of Queensland study into the pest's genetics.

15 May 2024

Transcriptomic Analysis Reveals Age-Dependent Gene Expression Patterns in Mouse Sweat Glands

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 8, entitled, "Characterization of age-associated gene expression changes in mouse sweat glands."

15 May 2024

Researchers Uncover More Genes Linked to Clonal Hematopoiesis

Researchers have identified 17 more genes that cause the aberrant proliferation of blood cells with mutations as humans age. The results were published in the journal Nature Genetics.

15 May 2024

Rice Study Sheds Light on Pseudogene Dynamics

Rice University's Peter Wolynes and his research team have unveiled a breakthrough in understanding how specific genetic sequences, known as pseudogenes, evolve.

14 May 2024

Harnessing High-Performance Computing to Unravel the Emergence of Novel Viruses

Suddenly they appear and - like the SARS-CoV-2 coronavirus - can trigger major epidemics: Viruses that nobody had on their radar.

14 May 2024

Decoding Chromatin Modifications: A Breakthrough in Epigenome Editing

An epigenome editing platform and a method to program nine major chromatin modifications.

14 May 2024

Study Reveals the Surprising Role of Spliceosomes in Introns' Journey

Although you may not appreciate them, or have even heard of them, throughout your body, countless microscopic machines called spliceosomes are hard at work.

13 May 2024

The Evolutionary Dynamics of Evolvability: Insights from Microevolution to Macroevolution

Ever since Darwin published his landmark theory of how species evolve, biologists have been fascinated with the intricate mechanisms that make evolution possible.

13 May 2024

Colossal Biosciences and University of Melbourne Partner to Save Northern Quolls from Invasive Cane Toads

Today scientists from Colossal Biosciences, the world’s first de-extinction company, and the University of Melbourne announce a major step forward in the effort to save Australia’s endangered northern quoll (Dasyurus hallucatus) from the invasive cane toad.

11 May 2024

Unraveling the Rhizobia-Diatom Relationship in the Ocean

Nitrogen is an essential component of all living organisms. It is also the key element controlling the growth of crops on land, as well as the microscopic oceanic plants that produce half the oxygen on our planet.

10 May 2024

Understanding Genome Scrambling in Oikopleura Dioica

When two animals look the same, eat the same, behave the same way, and live in similar environments, one might expect that they belong to the same species.

10 May 2024

Decoding Aging: The Role of Stochastic Variation in Biological Clocks

Aging clocks can measure the biological age of humans with high precision. Biological age can be influenced by environmental factors such as smoking or diet, thus deviating from the chronological age that is calculated using the date of birth.

10 May 2024

New Tool Precisely Edits Epigenetic Modifications

Powerful epigenetic editing technology was developed as a result of research by the Hackett group at EMBL Rome. This technology allows for the precise programming of chromatin modifications.

10 May 2024

Researchers Uncover New Genetic Mutation Linked to Rare Form of Congenital Thyroid Abnormality

A team of researchers from the University of Chicago, in collaboration with the Free University of Brussels and the University of Washington, have uncovered a genetic mutation in a non-coding region of DNA that alters the regulation of the thyroid, leading to a rare form of congenital thyroid abnormality.

9 May 2024

Genomics

Herpes Gene Therapy Achieves 90% Viral Reduction in Pre-Clinical Studies

Genetic Analysis Sheds Light on the Role of Ribosomal DNA Copy Number in Inflammation and Disease

Runt Transcription Factor Links Regeneration and Photosynthesis in Marine Worm-Algae Symbiosis

Discovery of Novel Adrenal Cell Type Linked to Monogamy in Oldfield Mice

Glycosylation and its Role in Human Health and Disease

Machine Learning Program Offers Insights Into Promoter Sequences and Transcription

Unlocking the Genetics of Coral-Destroying Crown-of-Thorns Starfish

Transcriptomic Analysis Reveals Age-Dependent Gene Expression Patterns in Mouse Sweat Glands

Researchers Uncover More Genes Linked to Clonal Hematopoiesis

Rice Study Sheds Light on Pseudogene Dynamics

Harnessing High-Performance Computing to Unravel the Emergence of Novel Viruses

Decoding Chromatin Modifications: A Breakthrough in Epigenome Editing

Study Reveals the Surprising Role of Spliceosomes in Introns' Journey

The Evolutionary Dynamics of Evolvability: Insights from Microevolution to Macroevolution

Colossal Biosciences and University of Melbourne Partner to Save Northern Quolls from Invasive Cane Toads

Unraveling the Rhizobia-Diatom Relationship in the Ocean

Understanding Genome Scrambling in Oikopleura Dioica

Decoding Aging: The Role of Stochastic Variation in Biological Clocks

New Tool Precisely Edits Epigenetic Modifications

Researchers Uncover New Genetic Mutation Linked to Rare Form of Congenital Thyroid Abnormality

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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