Genomics

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The First Programmable RNA-Guided System in Eukaryotes Uncovered

Feng Zhang of the Broad Institute at MIT and Harvard and the McGovern Institute for Brain Research at MIT headed a team of researchers who discovered the first programmable RNA-guided mechanism in eukaryotes, which include fungi, plants, and animals.

29 Jun 2023

Analyzing Glioma Progression and Implicating CPNs’ Long-Range Projections

Glioblastoma (GBM) is the most aggressive and lethal form of brain tumor. Despite treatment, GBM recurrence is inevitable and tends to occur outside surgical margins or in locations remote to the primary tumor, highlighting the central role played by tumor infiltration in this malicious disease.

29 Jun 2023

New Breakthrough of Genetic Marker Improves Treatment for Multiple Sclerosis

A study of more than 22,000 people with multiple sclerosis has discovered the first genetic variant associated with faster disease progression, which can rob patients of their mobility and independence over time.

29 Jun 2023

New Nanoparticle Developed Helps Improve the Delivery of mRNA-Based Vaccines

Johns Hopkins Medicine scientists say they have developed a nanoparticle -; an extremely tiny biodegradable container -; that has the potential to improve the delivery of messenger ribonucleic acid (mRNA)-based vaccines for infectious diseases such as COVID-19, and vaccines for treating non-infectious diseases including cancer.

29 Jun 2023

Disclosing the Key Role of Mitofusin 2 Cellular Makeup in Interconnecting Organelles Within Cells

Researchers at IRB Barcelona, the University of Barcelona (UB), VIMM, and the University of Padua unveil the key role of Mitofusin 2 cellular makeup in interconnecting organelles within cells.

29 Jun 2023

New AI-Assisted Methods to Discover Novel Deaminase Proteins with Unique Functions

At the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences, GAO Caixia’s group has introduced the use of artificial intelligence (AI)-assisted techniques to find out novel deaminase proteins with special functions via structural prediction and classification.

28 Jun 2023

New Computational Methods for Improving Alzheimer’s Disease Characterization

An improved method of subtyping Alzheimer’s disease based on genetic and tau PET imaging data has been developed computationally.

27 Jun 2023

Using Pressure to Understand RNA Dynamics

Similar to how there are limitless secrets in space, there is still a lot to discover when looking at biomolecules, which are one trillion times smaller than a meter.

23 Jun 2023

The Asgard Connection: New Research Uncovers the Origins of Complex Life

Thor, the legendary Norse god from the mythological city of Asgard, is not alone. According to groundbreaking research published in the journal Nature, we humans -; along with eagles, starfish, daisies and every complex organism on Earth -; are, in a sense, Asgardians.

23 Jun 2023

New Genetic Marker Could Predict Lenvatinib Resistance in Hepatocellular Carcinoma

A genetic marker discovered by UT Southwestern Medical Center researchers could help physicians predict which patients with hepatocellular carcinoma are most likely to develop resistance to the drug lenvatinib.

23 Jun 2023

New Technology can Help Probe the Connections Between the Brain and Gut

The brain and the digestive tract are in constant communication, relaying signals that help to control feeding and other behaviors.

23 Jun 2023

New Approach to Revolutionize Synthetic Biology

For the first time, scientists at the Lawrence Berkeley National Laboratory of the Department of Energy (Berkeley Lab) have created a genome-scale method to map the regulatory role of transcription factors, proteins that are essential for controlling gene expression, and a plant’s physiological features.

22 Jun 2023

Newly Found Disease Links Disruptions of Blood Formation, Immune System and Inflammation

In the quest to find the origin of the puzzling symptoms in four children, researchers from St. Anna Children's Cancer Research Institute, the CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences (ÖAW), and the Medical University of Vienna have discovered a completely new disease, linking disruptions of blood formation, the immune system, and inflammation.

22 Jun 2023

Albino Squid Illuminates Cephalopod Brain Activity

A team of researchers at the Marine Biological Laboratory (MBL) has successfully engineered an albino strain of Euprymna berryi, the hummingbird bobtail squid.

21 Jun 2023

Scientists Discover Candidate Genes for Disease Resistance in Wild Grape Plants

A team of scientists – including UC Irvine's Distinguished Professor of Ecology & Evolutionary Biology Brandon Gaut and UC Davis' Professors of Viticulture & Enology Dario Cantù and Andy Walker – has made a significant breakthrough in the battle against a devastating disease affecting grapevines.

20 Jun 2023

Detailed Genome Map to Prevent the Extinction of the Rusty Patched Bumblebee

Scientists from the United States Department of Agriculture (USDA) Agricultural Research Service (ARS) and the United States Fish and Wildlife Service (USFWS) have released a comprehensive, high-resolution map of the rusty patched bumble bees’ genome, supplying new approaches for saving the native pollinator from extinction.

20 Jun 2023