Genomics

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Researchers Generate Largest Atlas of Post-Zygotic Genome Mutations in Human Tissue Researchers Have ...

Researchers have created the largest atlas of post-zygotic genome mutations in healthy human tissue ever assembled -; a scientific advancement that could unlock new avenues for diagnosing and treating genetic disease.

17 Apr 2023

Next-Generation Sequencing Provides New Insights into Mutations of Mitochondrial DNA

A high-throughput single-cell single-mitochondrial genome sequencing technology known as iMiGseq has provided new insights into mutations of mitochondrial DNA (mtDNA) and offers a platform for assessing mtDNA editing strategies and genetic diagnosis of embryos prior to their implantation.

17 Apr 2023

New Mechanism Controlling Cellular Proliferation in Response to Serum Revealed

Researchers of the Genome Dynamics Project team at Tokyo Metropolitan Institute of Medical Science revealed new mechanism controlling cellular proliferation in response to serum, which triggers growth of resting cells.

13 Apr 2023

Comprehensive Sequencing of the Little Skate Genome

Rutgers geneticists, working with an international team of scientists, have conducted the most comprehensive sequencing yet of the complete DNA sequence of the little skate – which, like its better-known cousin, the stingray, has long been viewed as enigmatic because of its shape.

13 Apr 2023

Comparison of De Novo Proteins and Computer-Generated Proteins

Proteins are components of every cell. How they have changed in the course of evolution for the purpose of taking on new functions in the body, has long been a subject of research.

13 Apr 2023

Plant Response to Elevated Carbon Dioxide is Transgenerational and Orchestrated by DNA Methylation

New research lead by Keith Slotkin, PhD, member, Donald Danforth Plant Science Center opens the door for scientists to equip plants with the tools they need to adapt to rising levels of carbon dioxide (CO2), high heat, and other stressors associated with climate change.

12 Apr 2023

New Method for Improving Gene Therapy With Nanobubbles

Beyond vaccines, mRNA offers immense potential to fight disease, but targeting the genetic material to specific diseased cells is challenging-; requiring a new method.

12 Apr 2023

Exceptional Number of Unknown Viruses Found in the Infants' Feces

Viruses are usually associated with illness. But our bodies are full of both bacteria and viruses that constantly proliferate and interact with each other in our gastrointestinal tract.

12 Apr 2023

Artificial Light at Night Could Significantly Impact Mosquito Behavior

A new study's finding that urban light pollution may disrupt the winter dormancy period for mosquitoes that transmit West Nile virus could be considered both good news and bad news.

11 Apr 2023

Optimized Genome-Editing Method Vastly Reduces Mutations

CRISPR-Cas9 is frequently used to alter the genome by researching and editing disease-related genes. However, this approach is coupled with undesirable side effects including mutations and toxicity.

11 Apr 2023

CRISPR-Cas9 Driven Gene-Editing Tool Models Liver Cancer Tumor Subtypes

Mutations in human genes can cause serious issues, such as colon or liver cancer. However, cancer is a very complex condition. Mutations in the same genes can result in distinct kinds of cancers in different persons.

11 Apr 2023

Unraveling Regulatory Mechanisms When Plants Use Nitrogenous Fertilizers in the Roots

Insights into gene and protein control systems that regulate the use of nitrogen by plant roots could help develop crops that require less nitrogenous fertilizers to produce acceptable yields.

11 Apr 2023

Key Mediator of Anhedonia-Like Behavior Identified

Researchers uncovered a stress-regulated gene that is important in the relationship between chronic stress and typical depressed behavior in mice.

10 Apr 2023

Strawberry Inflorescence Research Provides Tools for Genomics-Based Plant Breeding

Researchers from the University of Helsinki, in collaboration with their Canadian colleagues, have demonstrated how strawberry inflorescence development is dictated by the small growing points, called meristems.

7 Apr 2023

Study Reveals a Unique Mode of Reproduction that Produces Chimeric Males in Yellow Crazy Ants

Male yellow crazy ants (Anoplolepis gracilipes) are chimeras of two separate genetic lineages, researchers report in a study that reveals a unique mode of reproduction in this species – one previously unknown to science.

7 Apr 2023

Novel Protein Involved in Tumor Suppression Identified

Understanding how cancer develops is critical for designing effective, personalized cancer therapies. Researchers have known for years that cancer begins with mutations in certain types of genes.

7 Apr 2023

Akili Labs and BGI Genomics Sign Agreement to Provide Southern Africa with Clinical-Grade Sequencing Solutions

Akili Labs (Pty) Ltd, a pioneer of cost-effective molecular diagnostics and secure genomic data storage solutions, and BGI Genomics Co. Ltd, the world's leading integrated solutions provider of precision medicine, today announced the signing of a technology transfer agreement that will provide the Southern region of Africa with clinical-grade sequencing solutions.

7 Apr 2023

Bacterial Probiotic for Treating and Preventing Stony Coral Tissue Loss Disease Discovered

Researchers with the Smithsonian's National Museum of Natural History have discovered the first effective bacterial probiotic for treating and preventing stony coral tissue loss disease (SCTLD), a mysterious ailment that has devastated Florida's coral reefs since 2014 and is rapidly spreading throughout the Caribbean.

6 Apr 2023

Obesity Influenced by Genetic Predisposition is Associated With Lower Risk of Cardiovascular Disease

The risk of developing cardiovascular disease is lower in people with obesity who have a genetic predisposition for high BMI than people with obesity influenced mainly by environmental factors such as lifestyle, researchers from Karolinska Institutet report in eClinical Medicine.

6 Apr 2023

Attacking the HTLV-1 Virus With the Help of Special Gene Scissors

HTLV-1 triggers aggressive forms of leukemia or an incurable spinal cord disease that leads to paralysis: the virus is the often ignored but no less insidious sibling of the HIV virus that causes AIDS and also belongs to the family of retroviruses.

6 Apr 2023

Genomics

Researchers Generate Largest Atlas of Post-Zygotic Genome Mutations in Human Tissue Researchers Have ...

Next-Generation Sequencing Provides New Insights into Mutations of Mitochondrial DNA

New Mechanism Controlling Cellular Proliferation in Response to Serum Revealed

Comprehensive Sequencing of the Little Skate Genome

Comparison of De Novo Proteins and Computer-Generated Proteins

Plant Response to Elevated Carbon Dioxide is Transgenerational and Orchestrated by DNA Methylation

New Method for Improving Gene Therapy With Nanobubbles

Exceptional Number of Unknown Viruses Found in the Infants' Feces

Artificial Light at Night Could Significantly Impact Mosquito Behavior

Optimized Genome-Editing Method Vastly Reduces Mutations

CRISPR-Cas9 Driven Gene-Editing Tool Models Liver Cancer Tumor Subtypes

Unraveling Regulatory Mechanisms When Plants Use Nitrogenous Fertilizers in the Roots

Key Mediator of Anhedonia-Like Behavior Identified

Strawberry Inflorescence Research Provides Tools for Genomics-Based Plant Breeding

Study Reveals a Unique Mode of Reproduction that Produces Chimeric Males in Yellow Crazy Ants

Novel Protein Involved in Tumor Suppression Identified

Akili Labs and BGI Genomics Sign Agreement to Provide Southern Africa with Clinical-Grade Sequencing Solutions

Bacterial Probiotic for Treating and Preventing Stony Coral Tissue Loss Disease Discovered

Obesity Influenced by Genetic Predisposition is Associated With Lower Risk of Cardiovascular Disease

Attacking the HTLV-1 Virus With the Help of Special Gene Scissors

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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