Genomics

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New technologies reveal cross-cutting breakdowns in Alzheimer’s disease

A figure from the paper depicts pathways perturbed in Alzheimer's disease. Below examples are listed for each pathway by major brain cell type. Image Credit: The Picower Institute.

4 Jan 2023

The detrimental effects of alcohol consumption during pregnancy

For the first time, researchers at the University of Helsinki in Finland examined the effects of prenatal alcohol exposure on the epigenome and gene function of the placenta. The epigenome is a molecular coating on a DNA strand that controls how genes are expressed.

4 Jan 2023

UCR researchers decode the secret language of photosynthesis

For decades, scientists have been stumped by the signals plants send themselves to initiate photosynthesis, the process of turning sunlight into sugars.

3 Jan 2023

VUMC’s BioVU achieves deep-freeze storage of more than 300,000 biological samples

BioVU, Vanderbilt University Medical Center's biobank, has reached another milestone -; deep-freeze storage of more than 300,000 biological samples.

20 Dec 2022

Genetic cause behind novel DEE syndrome discovered

Autism and epilepsy are two highly prevalent conditions that fall under the umbrella of neurodevelopmental disorders (NDD), which affect 1–3% of the world’s population just in terms of cognitive disabilities.

20 Dec 2022

New DNA analysis leads to first accurate tuberculosis genome identification

A novel genome assembly tool that has been created by researchers could lead to the creation of fresh antibiotics for the bacterial infections that cause tuberculosis and other diseases.

From Rutgers University 20 Dec 2022

Improving cancer immunotherapies with bioengineered synthetic gene circuits

In two distinct studies, scientists show how synthetic biology can be used to address a challenging problem in cancer immunotherapy: the way immunotherapy-related approaches focused on the short-term killing of tumor cells could fail to eradicate tumors because tumor growth occurs on longer timescales.

19 Dec 2022

Analyzing the value of global gene drive project registry

With the help of genetically modifying organisms in a lab, new strategies for managing pests, combating vector-borne diseases, and conserving the environment are being developed.

From UC San Diego 19 Dec 2022

Analysis of genetic factors contributing to cleft lip and palate

Cleft lip and palate, which are mainly caused by genetic reasons, are two of the most common congenital malformations. It is still unknown which genes are exactly affected.

19 Dec 2022

Octopuses' acuity may provide a critical link in understanding the evolution of complex life

Octopuses have captured the attention of scientists and the public with their remarkable intelligence, including the use of tools, engaging in creative play and problem-solving, and even escaping from aquariums.

16 Dec 2022

Analysis on the factor influencing the diatom P. tricornutum

Aquaculture frequently uses the commercially significant species Phaeodactylum tricornutum. It could also be used as biofuel in the future.

16 Dec 2022

Point-of-care program boosts genetic testing for prostate cancer

Certain prostate cancer patients have genetic mutations that could affect how they are treated. According to a study published in Urology Practice®, an Official Journal of the American Urological Association (AUA), a comprehensive, on-site genetic testing program developed by urologists could help close the gap for this underutilized resource.

16 Dec 2022

Simple inexpensive test determines the genetic susceptibility to PML

Four genetic mutations have been linked to progressive multifocal leukoencephalopathy (PML), a rare but sometimes fatal brain infection that can be provoked by dozens of FDA-approved drugs.

16 Dec 2022

Researchers gain insights into how density may change gene expression in some insects

A grasshopper hatched in a crowded environment may look and behave differently than a grasshopper hatched in isolation -; even if they have the same genes.

14 Dec 2022

Using CRISPR technology to reduce the symptoms of Huntington’s disease

A neurological condition called Huntington's disease (HD) results in a progressive decline in movement, coordination, and mental ability. It is brought on by a mutation in the huntingtin, or HTT, gene.

From UC San Diego 14 Dec 2022

Molecular regulation underlying emergency hematopoiesis uncovered

If the body’s emergency hematopoiesis program activates, it signifies an alert state of the immune system and serves two functions: In comparison to “normal mode” hematopoiesis, the emergency program results in enhanced replacement of immune cells consumed during infections or inflammations.

12 Dec 2022

Predictive classifier identifies patients who can skip radiation therapy

According to the findings of a meta-analysis proposed at the San Antonio Breast Cancer Symposium held on December 6–10th, 2022, patients with invasive breast cancer who had low scores on an investigational gene molecular signature seemed to have similar rates of local recurrence regardless of whether they received adjuvant radiation therapy after breast-conserving surgery.

12 Dec 2022