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Tailored Nanoparticles Deliver siRNA to Reduce Neuroinflammation in Alzheimer's Disease Models

Some Covid-19 vaccines safely and effectively used lipid nanoparticles (LNPs) to deliver messenger RNA to cells.

11 Dec 2023

Genetically Engineered Stem Cells May Revolutionize Parkinson's Disease Treatment

The future treatment of Parkinson’s Disease has undergone tremendous development in recent years. Now, a breakthrough in research has emerged, delivering the strongest results for both side-effect-free and long-lasting treatment effects.

7 Dec 2023

Brain Cell Genetics Drive Alzheimer's Progression

Developing treatments for Alzheimer's disease (AD) is difficult because complex underlying mechanisms drive different types of cells that may contribute to the disorder.

6 Dec 2023

Study Elucidates How Mutant NPM1 Protein Drives Leukemia by Activating Autophagy System

In a recent study, scientists led by Professor Stefan Müller from Goethe University's Institute of Biochemistry II investigated a specific form of blood cancer known as acute myeloid leukemia, or AML.

5 Dec 2023

Pancreatic Nerve Zaps Restore Insulin Production and Reverse Diabetes in Mice

Insulin is a hormone that decreases blood glucose levels. The only cells that produce insulin are pancreatic beta cells (β-cells), and a decrease in these cells is a major cause of diabetes.

5 Dec 2023

Misfolded Proteins: How They Damage Neurons and Cause Neurodegeneration

Neurodegenerative diseases are characterized by the deposition of clumped proteins in the brain and progressive neuronal cell death.

5 Dec 2023

Presage Biosciences and AstraZeneca Partner to Advance Immuno-Oncology Research for Head and Neck Cancer

Presage Biosciences, a pioneering translational oncology company whose mission is to use CIVO and spatial molecular profiling to understand the complexity of drug response in the tumor microenvironment (TME), has entered into an agreement with AstraZeneca, a global biopharmaceutical company.

1 Dec 2023

"Wake" Slow Waves may Decrease the Impact of Epileptic Spikes on Brain Activity

Slow waves that usually only occur in the brain during sleep are also present during wakefulness in people with epilepsy and may protect against increased brain excitability associated with the condition, finds a new study led by researchers at UCL.

30 Nov 2023

Nutrient Derived From Meat and Dairy Enhances Cancer Killing Ability of Immune Cells

Trans-vaccenic acid (TVA), a long-chain fatty acid found in meat and dairy products from grazing animals such as cows and sheep, improves the ability of CD8+ T cells to infiltrate tumors and kill cancer cells, according to a new study by researchers from the University of Chicago.

27 Nov 2023

Scientists Discover New Class of Molecular Glue Degraders for Cancer Therapy

Cells contain molecular machinery that targets and disposes of unwanted proteins to maintain homeostasis.

17 Nov 2023

Gene Splicing Affects CD20 Expression and Response to Cancer Immunotherapy

Immunotherapies that target the CD20 antigen have revolutionized how patients with a variety of blood cancers and hematologic disorders have been treated.

17 Nov 2023

Study Uncovers Ancestry-Specific Genetic Factors in IBD

The advent of whole genome sequencing technology has prompted an explosion in research into how genetics are associated with disease risk.

17 Nov 2023

Wilmot Researchers Uncover a "Genomic Tug of War" That Influences Decitabine's Effectiveness

Some patients with myelodysplastic syndromes, like acute myeloid leukemia, benefit from a chemotherapy drug called decitabine that stunts cancer growth. But many others are resistant to decatibine's effects or become resistant over time.

17 Nov 2023

Circular Extrachromosomal DNA Linked to Medulloblastoma Relapse and Death

A study of newly created databases of medulloblastoma has found that patients with tumors containing circular extrachromosomal DNA-;loops of DNA found outside of regular chromosomes-;are twice as likely to relapse and three times as likely to die within five years of diagnosis.

15 Nov 2023

Cancer Stem Cells Induce Macrophage Senescence, Creating Conditions for Tumor Formation

Cancer stem cells cause the aging of macrophages in mice with healthy immune systems, creating conditions for the formation of tumors.

15 Nov 2023

Rare Genetic Variant Found to Protect Against Alzheimer's Disease

Researchers at Gladstone Institutes have discovered that a rare genetic variant known as the "Christchurch mutation" can block detrimental effects of apolipoprotein E4, the best-established risk factor for the most common form of Alzheimer's disease.

14 Nov 2023

New Drug-Like Molecule Enhances Mitophagy, Protects Against Neurodegeneration

Having healthy mitochondria, the organelles that produce energy in all our cells, usually portends a long healthy life whether in humans or in C. elegans, a tiny, short-lived nematode worm often used to study the aging process.

14 Nov 2023

Stanford Researchers Discover New Mechanism for Breast Cancer Invasion

The majority of breast cancers start in the lining of a breast milk duct and, if they remain there, are very treatable.

14 Nov 2023

Scientists Identify 4,749 Gene Clusters Linked to Cancer Prognosis

Researchers at the Mount Sinai Center for Transformative Disease Modeling have released a groundbreaking study identifying 4,749 key gene clusters, termed "prognostic modules," that significantly influence the progression of 32 different types of cancer.

14 Nov 2023

New Insights Into Tumor-Immune Interactions Could Lead to More Effective Therapies for Multiple Myeloma

A multicenter study led by researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine shows how interactions between tumor cells and immune components of the microenvironment can impact treatment responses and outcomes in patients newly diagnosed with multiple myeloma who undergo combination treatments that include targeted immunotherapy.

10 Nov 2023

Medical Condition News

Tailored Nanoparticles Deliver siRNA to Reduce Neuroinflammation in Alzheimer's Disease Models

Genetically Engineered Stem Cells May Revolutionize Parkinson's Disease Treatment

Brain Cell Genetics Drive Alzheimer's Progression

Study Elucidates How Mutant NPM1 Protein Drives Leukemia by Activating Autophagy System

Pancreatic Nerve Zaps Restore Insulin Production and Reverse Diabetes in Mice

Misfolded Proteins: How They Damage Neurons and Cause Neurodegeneration

Presage Biosciences and AstraZeneca Partner to Advance Immuno-Oncology Research for Head and Neck Cancer

"Wake" Slow Waves may Decrease the Impact of Epileptic Spikes on Brain Activity

Nutrient Derived From Meat and Dairy Enhances Cancer Killing Ability of Immune Cells

Scientists Discover New Class of Molecular Glue Degraders for Cancer Therapy

Gene Splicing Affects CD20 Expression and Response to Cancer Immunotherapy

Study Uncovers Ancestry-Specific Genetic Factors in IBD

Wilmot Researchers Uncover a "Genomic Tug of War" That Influences Decitabine's Effectiveness

Circular Extrachromosomal DNA Linked to Medulloblastoma Relapse and Death

Cancer Stem Cells Induce Macrophage Senescence, Creating Conditions for Tumor Formation

Rare Genetic Variant Found to Protect Against Alzheimer's Disease

New Drug-Like Molecule Enhances Mitophagy, Protects Against Neurodegeneration

Stanford Researchers Discover New Mechanism for Breast Cancer Invasion

Scientists Identify 4,749 Gene Clusters Linked to Cancer Prognosis

New Insights Into Tumor-Immune Interactions Could Lead to More Effective Therapies for Multiple Myeloma

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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