Molecular & Structural Biology

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New Model Hopes to Shed Light on Life's First Self-Organization

A new study conducted by researchers from the Max Planck Institute for Dynamics and Self-Organization (MPI-DS) found that catalytic molecules can form metabolically active clusters by generating and following concentration gradients.

7 Aug 2023

RNA Modification in Driving Pancreatic Cancer Growth

RNA molecules can undergo chemical changes like m6A, which can have a significant influence on gene expression and affect several aspects of cancer development and progression

7 Aug 2023

Revealing a Novel Signaling Pathway Fostering Aging-Related Chronic Metabolic Disorders

Korean researchers have unveiled a novel signaling pathway that fosters aging-related chronic metabolic disorders.

4 Aug 2023

Study Shows How Sensory Neurons Control Gastrointestinal Tracts

Gastrointestinal and digestive issues impact roughly 3 million people across the United States alone, and that number is growing.

4 Aug 2023

How the Tropical Red Swamp Crayfish Successfully Invaded the Cold Regions of Japan

Researchers from Japan have identified the molecular mechanisms that allow the red swamp crayfish to develop cold tolerance and, thus, colonize cold regions.

3 Aug 2023

Using a New Class of Molecules to Combat Antimicrobial Resistance

Since most therapeutic medicines no longer work against harmful bacteria, the World Health Organization has classified antimicrobial resistance as a worldwide problem.

1 Aug 2023

Scientists Develop DNA Barcoding for Caragana Genus

In the family of legumes, the genus Caragana is significant both ecologically and pharmacologically. On the entire Asian continent, Caragana is essential to the ecosystem of the cold desert. However, it has proven difficult to correctly identify the genus’ taxa.

31 Jul 2023

New Insights Into Lactate Transporters and Their Therapeutic Potential

Researchers from the Giulio Superti-Furga Lab at CeMM, the Austrian Academy of Sciences’ Research Center for Molecular Medicine, have developed a new technique for identifying specific inhibitors of a lactate transporter linked to cancer and other diseases.

31 Jul 2023

New Method Facilitates Early Detection and Localization of Tumors

To help with early tumor diagnosis and tumor localization, researchers have devised a technology that concurrently detects many cancer-specific DNA circulating hallmarks.

26 Jul 2023

New Class of Brain Inhibitory Neurons May Contribute to Autism and Schizophrenia

A University of California, Irvine-led team of researchers working at the Center for Neural Circuit Mapping find links between brain disorders and dysfunction of newly identified inhibitory brain cell types.

26 Jul 2023

LION™-Formulated repRNA in Next-Gen repRNA Vaccine Platform Appears Promising

The creation of new vaccination technologies continues to be at the forefront of scientific inquiry as the globe fights numerous infectious illnesses. Recent research on illnesses like COVID-19 has shown promise for mRNA-based vaccines and their use of lipid nanoparticles (LNPs) for delivery.

25 Jul 2023

Atomic-Level Analysis of Synthetic DNA to Reveal New Treatment Options

West Virginia University researchers can now see synthetic DNA at the atomic level, allowing them to learn how to tweak its structure to improve its scissor-like function.

25 Jul 2023

New Protein Found to be Key to Proper Functioning of Acinar Cells

The energy supply in the body has been regulated by the pancreas, located behind the stomach. This mechanism happens by secreting proteins (enzymes) accountable for glucose–the body’s primary fuel–reaching other organs when needed and in the exact amount.

24 Jul 2023

New Method for Building Modular Optical Sensors to Detect Bacteria and Viruses

An innovative method for building modular optical sensors that can detect viruses and bacteria has been created by an interdisciplinary research team from Bochum, Duisburg, and Zurich.

24 Jul 2023

The First Data Set Decoding RNA-Driven Phase Separations

High levels of semi-extractable RNAs are present in membraneless organelles in cells, and these RNAs could one day serve as biomarkers or therapeutic targets.

19 Jul 2023

Uncovering New Insights into Virus Self-Assembly

Griffith University researchers were instrumental in controlling the way viruses are assembled by using DNA “origami” templates.

18 Jul 2023

New Study Identifies Aerobic Glycolysis Vital for Eye Development

According to a recent Northwestern Medicine study published in Nature Communications, aerobic glycolysis, the process by which cells convert glucose into lactate, is essential for eye development in mammals.

17 Jul 2023

5-ALA Opens New Avenues for Treating Mitochondrial Disorders

At the Tokyo Metropolitan University, researchers have shown that 5-aminolevulinic acid (5-ALA) aids bypass deficiencies in Complex I (CI), the first in a series of protein complexes that transport electrons and assist in powering the mitochondria.

17 Jul 2023

New Insights into the Regulatory Network of Th17 Cells

N6-methyladenosine (m6A) is the most extensively studied RNA modification across multiple species, and its importance in the immune system has been demonstrated in a variety of contexts, including mRNA metabolism, cell differentiation, proliferation, and response to stimulation.

17 Jul 2023