Molecular & Structural Biology

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Revealing How Human Brains Encode and Retain Value-Based Information

Researchers from the Center for Cognition and Sociality (CCS) within the Institute for Basic Science (IBS) recently announced the discovery of neurons that allow us to recognize others. The research team discovered that the neurons that deal with the information associated with different individuals are located in the CA1 region of the hippocampus.

2 Jun 2023

Machine Learning-Based Tool Allows Scientists to Quickly Model Families of Proteins

Microbes drive key processes of life on Earth. They affect global elemental cycles-;the movement of carbon, nitrogen, and other elements. They also promote plant growth and affect the development of diseases. These roles are essential in every ecosystem.

2 Jun 2023

RNA Regulatory Mechanism Involving Stress Granules Directly Regulates Alzheimer’s Development

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 10, entitled, "Stress granules sequester Alzheimer's disease-associated gene transcripts and regulate disease-related neuronal proteostasis."

2 Jun 2023

Antioxidant Enzymes Relocate to the Nucleus in Response to DNA Damage

In crisis, the nucleus calls antioxidant enzymes to the rescue. The nucleus being metabolically active is a profound paradigm shift with implications for cancer research.

2 Jun 2023

Unraveling How Bivalves Evolved Among Many Others During the Cambrian Explosion

Every so often, life on Earth steps onto a nearly empty playing field and faces a spectacular opportunity.

31 May 2023

New Algorithm to Improve the Understanding of Protein Movements

Proteins are biological molecules that perform almost all biochemical tasks in all forms of life. In doing so, the tiny structures perform ultra-fast movements.

31 May 2023

Ancient DNA Reveals Earliest Evidence of Plague Cases in Britain

The Francis Crick Institute has discovered three 4,000-year-old British cases of Yersinia pestis, the bacteria that causes the plague—the oldest evidence of the plague in Britain to date. The study was published in Nature Communications.

31 May 2023

Characterizing a Pivotal Time in Mammalian Embryonic Development

Many of life’s secrets are hidden in the initial stages of embryonic development. Unraveling these mysteries can aid in the understanding of early development and birth abnormalities, as well as the creation of innovative regenerative medicine treatments.

31 May 2023

Game-Changing Research Shows Astrocytes as Key Regulators of Alzheimer's Disease Progression

Why do some people develop Alzheimer's disease while others don't? And, even more puzzlingly, why do many individuals whose brains are chock-full of toxic amyloid aggregates-;a telltale sign of Alzheimer's brain pathology-;never go on to develop Alzheimer's-associated dementias?

30 May 2023

Study Reveals Mechanisms Behind Swallowing in Detail

Sensory cells in the vagus nerve can detect and locate food in the esophagus. Their signals help transport the food onward to the stomach. Signal failure leads to swallowing disorders, say a team led by Carmen Birchmeier at the Max Delbrück Center.

29 May 2023

New Insight Into Cellular Waste Disposal Process

To prevent our body's cells from overflowing with garbage and to keep them healthy, the waste inside them is constantly being disposed of.

25 May 2023

How Epigenetic Landscape Impacts Pioneer Transcription Factor Binding

St. Jude Children’s Research Hospital researchers are investigating how a type of transcription factor known as a pioneer transcription factor reaches DNA even when it is tightly wrapped.

25 May 2023

Breakthrough Discovery Paves Way for Understanding Downstream Cellular Applications in Human Health

Assemblies of tiny molecular proteins span the membranes that encapsulate our cells, directing cellular activities and regulating the transport of materials and information in and out.

25 May 2023

Research Uncovers the Biology Underpinning a Rare Genetic Mutation Linked to Painlessness

The biology underpinning a rare genetic mutation that allows its carrier to live virtually pain-free, heal more rapidly and experience reduced anxiety and fear, has been uncovered by new research from UCL.

24 May 2023

Cytoelectric Coupling: Electrical Fields Influence Physical Configuration of Neurons' Sub-Cellular Components

To produce its many functions, including thought, the brain works at many scales. Information such as goals or images is represented by coordinated electrical activity among networks of neurons, while within and around each neuron a mix of proteins and other chemicals physically carries out the mechanics of participating in the network.

23 May 2023

New Insight into the Dynamics of a Ribosomal Protein - RPL3L

A team of researchers have discovered that a mutation in a ribosomal protein found specifically in heart and skeletal muscle leads to impaired cardiac contractility in mice.

23 May 2023

Researchers Develop AI Method to Predict Small Molecule Substrates of Enzymes

Enzymes are the molecule factories in biological cells. However, which basic molecular building blocks they use to assemble target molecules is often unknown and difficult to measure.

23 May 2023

Key Event that Controls the Timing of the Biological Clock Identified

Molecular clocks in our cells synchronize our bodies with the cycle of night and day, cue us for sleep and waking, and drive daily cycles in virtually every aspect of our physiology. Scientists studying the molecular mechanisms of our biological clocks have now identified a key event that controls the timing of the clock.

23 May 2023

Study Examines the Role of Neuronal Diversity in Cognitive Functions

Neurons in a key area of the brain have different functions based on their exact genetic identity, and understanding this diversity could lead to better understanding of the brain's computational flexibility and memory capacity, potentially informing disease treatment options, Cornell researchers report in a new study.

23 May 2023

Investigators Characterize and Name the Protein Domain that Governs Collagen Transport

Discovery of the MOTH domain offers insights into evolution. This is because both insects and vertebrates need collagen in their connective tissue.

23 May 2023

Molecular & Structural Biology

Revealing How Human Brains Encode and Retain Value-Based Information

Machine Learning-Based Tool Allows Scientists to Quickly Model Families of Proteins

RNA Regulatory Mechanism Involving Stress Granules Directly Regulates Alzheimer’s Development

Antioxidant Enzymes Relocate to the Nucleus in Response to DNA Damage

Unraveling How Bivalves Evolved Among Many Others During the Cambrian Explosion

New Algorithm to Improve the Understanding of Protein Movements

Ancient DNA Reveals Earliest Evidence of Plague Cases in Britain

Characterizing a Pivotal Time in Mammalian Embryonic Development

Game-Changing Research Shows Astrocytes as Key Regulators of Alzheimer's Disease Progression

Study Reveals Mechanisms Behind Swallowing in Detail

New Insight Into Cellular Waste Disposal Process

How Epigenetic Landscape Impacts Pioneer Transcription Factor Binding

Breakthrough Discovery Paves Way for Understanding Downstream Cellular Applications in Human Health

Research Uncovers the Biology Underpinning a Rare Genetic Mutation Linked to Painlessness

Cytoelectric Coupling: Electrical Fields Influence Physical Configuration of Neurons' Sub-Cellular Components

New Insight into the Dynamics of a Ribosomal Protein - RPL3L

Researchers Develop AI Method to Predict Small Molecule Substrates of Enzymes

Key Event that Controls the Timing of the Biological Clock Identified

Study Examines the Role of Neuronal Diversity in Cognitive Functions

Investigators Characterize and Name the Protein Domain that Governs Collagen Transport

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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