Molecular & Structural Biology

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Breakthrough Discovery Paves Way for Understanding Downstream Cellular Applications in Human Health

Assemblies of tiny molecular proteins span the membranes that encapsulate our cells, directing cellular activities and regulating the transport of materials and information in and out.

25 May 2023

Research Uncovers the Biology Underpinning a Rare Genetic Mutation Linked to Painlessness

The biology underpinning a rare genetic mutation that allows its carrier to live virtually pain-free, heal more rapidly and experience reduced anxiety and fear, has been uncovered by new research from UCL.

24 May 2023

Cytoelectric Coupling: Electrical Fields Influence Physical Configuration of Neurons' Sub-Cellular Components

To produce its many functions, including thought, the brain works at many scales. Information such as goals or images is represented by coordinated electrical activity among networks of neurons, while within and around each neuron a mix of proteins and other chemicals physically carries out the mechanics of participating in the network.

23 May 2023

New Insight into the Dynamics of a Ribosomal Protein - RPL3L

A team of researchers have discovered that a mutation in a ribosomal protein found specifically in heart and skeletal muscle leads to impaired cardiac contractility in mice.

23 May 2023

Researchers Develop AI Method to Predict Small Molecule Substrates of Enzymes

Enzymes are the molecule factories in biological cells. However, which basic molecular building blocks they use to assemble target molecules is often unknown and difficult to measure.

23 May 2023

Key Event that Controls the Timing of the Biological Clock Identified

Molecular clocks in our cells synchronize our bodies with the cycle of night and day, cue us for sleep and waking, and drive daily cycles in virtually every aspect of our physiology. Scientists studying the molecular mechanisms of our biological clocks have now identified a key event that controls the timing of the clock.

23 May 2023

Study Examines the Role of Neuronal Diversity in Cognitive Functions

Neurons in a key area of the brain have different functions based on their exact genetic identity, and understanding this diversity could lead to better understanding of the brain's computational flexibility and memory capacity, potentially informing disease treatment options, Cornell researchers report in a new study.

23 May 2023

Investigators Characterize and Name the Protein Domain that Governs Collagen Transport

Discovery of the MOTH domain offers insights into evolution. This is because both insects and vertebrates need collagen in their connective tissue.

23 May 2023

Researchers Examine the Role of TOR in LR Formation and its Interplay with Auxin Signaling

Along with sugar reallocation, a basic molecular mechanism within plants controls the formation of new lateral roots. An international team of plant biologists has demonstrated that it is based on the activity of a certain factor, the target of rapamycin (TOR) protein. A better understanding of the processes that regulate root branching at the molecular level could contribute to improving plant growth and therefore crop yields, according to research team leader Prof. Dr Alexis Maizel of the Centre for Organismal Studies at Heidelberg University.

23 May 2023

Revealing the Molecular and Cellular Underpinnings of Summit Disease

Carolyn Elya, a Postdoctoral Researcher in the Department of Organismic and Evolutionary Biology at Harvard, illustrates the molecular and cellular underpinnings of the parasitic fungus Entomophthora muscae’s (E. muscae’s) ability to influence the behavior of fruit flies in new research published in eLife.

22 May 2023

Protein Discovery Could Lead to Better Treatment for Females with PTSD

From humans to plants to single-cell organisms, there's a protein that rules them all.

22 May 2023

Machine Learning Reveals Sex-Specific Genes, Molecular Pathways Linked to Alzheimer's Disease Progression

Alzheimer's Disease (AD) is a complex neurodegenerative illness with genetic and environmental origins.

22 May 2023

TTUHSC Professor Awarded NIH Grant for Potassium Channel Study

Each living cell has small, highly specialized conduits called potassium (K+) channels, which are responsible for the highly selective and fast transfer of K+ ions across cell membranes.

19 May 2023

Researchers Discover How Deadly Hospital Pathogen can Survive Harsh Environments

The deadly hospital pathogen Acinetobacter baumannii can live for a year on a hospital wall without food and water. Then, when it infects a vulnerable patient, it resists antibiotics as well as the body's built-in infection-fighting response.

17 May 2023

Study Provides a New Picture of How Bacterial Cells Repair Faulty DNA

A new study adds to an emerging, radically new picture of how bacterial cells continually repair faulty sections of their DNA.

17 May 2023

Brain-Wide Mapping Reveals How Serotonin Affects Animal Behavior

Because serotonin is one of the primary chemicals the brain uses to influence mood and behavior, it is also the most common target of psychiatric drugs.

16 May 2023

Study Finds Place of Transcription Start Often Determines the Place of Transcription End

Each gene in the human DNA has a start and an endpoint. It is critical to correctly define the gene's extremities to make functional proteins. Much study has been conducted to identify what determines when, where, and at which place on the DNA a gene “starts.”

16 May 2023

Molecular & Structural Biology

Breakthrough Discovery Paves Way for Understanding Downstream Cellular Applications in Human Health

Research Uncovers the Biology Underpinning a Rare Genetic Mutation Linked to Painlessness

Cytoelectric Coupling: Electrical Fields Influence Physical Configuration of Neurons' Sub-Cellular Components

New Insight into the Dynamics of a Ribosomal Protein - RPL3L

Researchers Develop AI Method to Predict Small Molecule Substrates of Enzymes

Key Event that Controls the Timing of the Biological Clock Identified

Study Examines the Role of Neuronal Diversity in Cognitive Functions

Investigators Characterize and Name the Protein Domain that Governs Collagen Transport

Researchers Examine the Role of TOR in LR Formation and its Interplay with Auxin Signaling

Revealing the Molecular and Cellular Underpinnings of Summit Disease

Protein Discovery Could Lead to Better Treatment for Females with PTSD

Machine Learning Reveals Sex-Specific Genes, Molecular Pathways Linked to Alzheimer's Disease Progression

TTUHSC Professor Awarded NIH Grant for Potassium Channel Study

Researchers Discover How Deadly Hospital Pathogen can Survive Harsh Environments

Study Provides a New Picture of How Bacterial Cells Repair Faulty DNA

Brain-Wide Mapping Reveals How Serotonin Affects Animal Behavior

Study Finds Place of Transcription Start Often Determines the Place of Transcription End

New Method for Analyzing Protein Crystals Could Open Up Applications for Drug Discovery

AI Used to Create 3D Model of 'Postal Workers' in Human Cells

How the Natural Process of DNA Repair Fails to Cause Disease

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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