Molecular & Structural Biology

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Novel Way of Collecting Highly Detailed Information About Organic Tissues

An innovative technology created by USC Michelson Center for Convergent Bioscience researchers proposes a new way of acquiring and arranging highly comprehensive information about organic tissues in record time.

5 Apr 2023

Experts Develop a New Mesoscopic Simulation Model of DNA Movement

The mesoscopic scale in physics and chemistry relates to the length scale on which the properties of a material or phenomenon can be researched without delving into the behaviour of individual atoms.

5 Apr 2023

Revealing how cohesin attaches to the DNA and forms loops

Ana Losada, a scientist at the Spanish National Cancer Research Centre (CNIO) and then at the Cold Spring Harbor Laboratory, identified cohesin, a protein essential to the process of cell division, in Xenopus frogs at the end of the 1990s.

5 Apr 2023

Tiny Protein Interacts with Ion Channels to Make Our Eyes Sensitive to Dim Light

Using cryo-electron microscopy and mass spectrometry, researchers from PSI have deciphered the structure of an ion channel found in the eye while it interacts with the protein calmodulin – a structure that has eluded scientists for three decades.

4 Apr 2023

Designing a Lipid Nanoparticle to Safely Deliver mRNA to the Pancreas

Therapeutics that use mRNA-;like some of the COVID-19 vaccines-;have enormous potential for the prevention and treatment of many diseases.

4 Apr 2023

Researchers Uncover a New, Direction-Dependent Friction in Proteins

An interdisciplinary research team of the Institutes of Physical Chemistry and Physics of the University of Freiburg and the Max Planck Institute of Biophysics in Frankfurt-am-Main has discovered a new, direction-dependent friction in proteins called anisotropic friction.

3 Apr 2023

Tighter Core of SARS-CoV-2 Spike Protein in New Variants Likely Improved the Virus's Ability to Infect Host Cells

Just as a tight core is a component of good physical fitness for humans, helping to stabilize our bodies, mutations that tightened the core of the SARS-CoV-2 spike protein in new variants may have increased the virus's fitness.

3 Apr 2023

Study brings into sharper focus the structural details of SARS-COV-2 virus

A new study led by Worcester Polytechnic Institute (WPI) brings into sharper focus the structural details of the COVID-19 virus, revealing an elliptical shape that "breathes," or changes shape, as it moves in the body.

31 Mar 2023

Newly developed toolkit uses small molecules to control the activity of synthetic RNA

The Okinawa Institute of Science and Technology, in collaboration with Astellas Pharma Inc., has developed a new toolkit that uses small molecules to control the activity of a piece of synthetic RNA, and ultimately regulate gene expression.

31 Mar 2023

First atomic-level structure of 'oil-eating' enzyme paves way for bioengineered catalysts

Scientists at the U.S. Department of Energy's Brookhaven National Laboratory have produced the first atomic-level structure of an enzyme that selectively cuts carbon-hydrogen bonds-;the first and most challenging step in turning simple hydrocarbons into more useful chemicals.

31 Mar 2023

Harnessing a natural bacterial system to deliver proteins in mice and human cells

Researchers at the Broad Institute of MIT and Harvard and the McGovern Institute for Brain Research at MIT have harnessed a natural bacterial system to develop a new protein delivery approach that works in human cells and animals.

30 Mar 2023

Research shows how the fruit fly gut builds a cozy niche to selectively promote colonization

The digestive tract of fruit flies remodels itself to accommodate beneficial microbiome species and maintain long-term stability of the gut environment, according to new research led by Carnegie's William Ludington and Allan Spradling.

30 Mar 2023

Study helps understand at the cellular level how physical activity contributes to fitness during aging

Regular exercise can guarantee quality of life and longevity, specialists agree. However, exactly how exercise influences the functioning of muscle cells is poorly understood.

30 Mar 2023

Epigenetic fingerprinting helps trace the origin of animal products

Food analysis laboratories can provide an answer to questions like “Was the salmon for dinner really caught wild or did it come from aquaculture? What to make of the alleged ‘biolabel quality’ of the shrimp for the seafood salad? And was the chicken for the Sunday roast really allowed to spend its life in the open air?” to a limited extent.

30 Mar 2023

New inhibitor molecule disrupts the infection mechanism of SARS-CoV-2 coronavirus

A team of scientists led by the Department of Energy's Oak Ridge National Laboratory designed a molecule that disrupts the infection mechanism of the SARS-CoV-2 coronavirus and could be used to develop new treatments for COVID-19 and other viral diseases.

29 Mar 2023

New project addresses the lack of standards for optimal management of Lp(a)

According to a recent scientific statement gathered from American Heart Association, high levels of lipoprotein(a) [Lp(a)] are known to be a separate, chiefly inherited and causal risk factor for cardiovascular disease, known to be the leading cause of death and disability around the world.

29 Mar 2023

Molecular & Structural Biology

Novel Way of Collecting Highly Detailed Information About Organic Tissues

Experts Develop a New Mesoscopic Simulation Model of DNA Movement

Revealing how cohesin attaches to the DNA and forms loops

Tiny Protein Interacts with Ion Channels to Make Our Eyes Sensitive to Dim Light

Designing a Lipid Nanoparticle to Safely Deliver mRNA to the Pancreas

Researchers Uncover a New, Direction-Dependent Friction in Proteins

Tighter Core of SARS-CoV-2 Spike Protein in New Variants Likely Improved the Virus's Ability to Infect Host Cells

Study brings into sharper focus the structural details of SARS-COV-2 virus

Newly developed toolkit uses small molecules to control the activity of synthetic RNA

First atomic-level structure of 'oil-eating' enzyme paves way for bioengineered catalysts

Harnessing a natural bacterial system to deliver proteins in mice and human cells

Research shows how the fruit fly gut builds a cozy niche to selectively promote colonization

Study helps understand at the cellular level how physical activity contributes to fitness during aging

Epigenetic fingerprinting helps trace the origin of animal products

New inhibitor molecule disrupts the infection mechanism of SARS-CoV-2 coronavirus

New project addresses the lack of standards for optimal management of Lp(a)

Heart-healthy benefits of walnuts may be linked to beneficial changes in the mix of gut microbes

New insights into how different countries' research establishments respond to disease outbreaks

New breakthrough in controlling plant responses to temperature

Eye color genes play important roles in maintaining retinal health

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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