Molecular & Structural Biology

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Study analyzes the role of heart cell protein as a potential therapeutic for heart failure

Recent research identified that a protein involved in regulating calcium signaling within heart cells can play a vital role in the prevention of chronic heart failure.

From The University of Utah 29 Jul 2021

Study: Biomarker can predict response to immunotherapies in breast cancer patients

A biomarker that has proven to be a predictor for response to immunotherapies in melanoma patients also has clinical relevance for breast cancer patients, according to a new study published in Clinical Cancer Research, a journal of the American Association for Cancer Research.

28 Jul 2021

New formulation to administer antibodies for choroidal neovascularization therapy

Scientists have created a new formulation based on regulatory T-cell exosomes (rEXS) to administer vascular endothelial growth factor (VEGF) antibodies.

28 Jul 2021

Research group analyzes methods to tackle antibiotic resistance

One major threat that the world faces and researchers are working to combat today is antibiotic resistance, and six CSRI students are doing their part in the fight.

28 Jul 2021

New thin-film microfluidic device to manipulate β-lactoglobulin in milk

Researchers have manipulated beta-lactoglobulin, or β-lactoglobulin, by using an Australian-made innovative thin-film microfluidic device.

27 Jul 2021

Researchers develop repository showcasing antibody activity on spike protein variants

Scientists have created an “atlas” that charts how 152 different antibodies attack a major piece of the SARS-CoV-2 machinery, the spike protein.

27 Jul 2021

Study identifies the role of lysosomes in the spread of Parkinson’s disease

In the past few decades, neurodegenerative diseases have turned into one of the top 10 worldwide causes of death.

26 Jul 2021

Study reveals the role of transcription in shaping the genome

Developments in the field of microscopy allowed scientists to picture loops of DNA strands for the first time.

26 Jul 2021

Yeast study reveals a protein involved in gross chromosomal rearrangements

Gross chromosomal rearrangements--where portions of the genome become moved, deleted, or inverted--can lead to cell death and diseases such as cancer in complex multicellular organisms.

23 Jul 2021

New insights on an enzyme complex involved in plaque production

A research team led by Wim Annaert (VIB-KU Leuven) uncovered the early assembly of gamma-secretase, a protein complex linked to numerous cellular processes including the development of Alzheimer's disease.

23 Jul 2021

Study reveals SARS-CoV-2 variant is less sensitive to inhibition by antibodies

SARS-CoV-2 is still a major threat to humankind. The constant emergence of variants makes the threat made by the virus difficult to estimate. The SARS-CoV-2 variant B.1.617 spread in India and gave rise to the Delta variant, B.1.617.2, which is now dominant in numerous countries.

23 Jul 2021

Researchers successfully create genetically engineered marsupials via genome editing

Scientists from the RIKEN Center for Biosystems Dynamics Research (BDR) successfully created the first genetically engineered marsupial. The research and its findings published in the Current Biology journal help decipher the genetic background of special characteristics found only in marsupials.

23 Jul 2021

Molecular & Structural Biology

Study analyzes the role of heart cell protein as a potential therapeutic for heart failure

Study: Biomarker can predict response to immunotherapies in breast cancer patients

New formulation to administer antibodies for choroidal neovascularization therapy

Research group analyzes methods to tackle antibiotic resistance

New thin-film microfluidic device to manipulate β-lactoglobulin in milk

Researchers develop repository showcasing antibody activity on spike protein variants

Study identifies the role of lysosomes in the spread of Parkinson’s disease

Study reveals the role of transcription in shaping the genome

Yeast study reveals a protein involved in gross chromosomal rearrangements

New insights on an enzyme complex involved in plaque production

Study reveals SARS-CoV-2 variant is less sensitive to inhibition by antibodies

Researchers successfully create genetically engineered marsupials via genome editing

SARS-CoV-2 variant B.1.617 can infect lung and intestinal cells more efficiently than the original virus

Researchers discover nucleotide sequences characteristic of microRNA isoforms

Study identifies many small molecules that bind to certain areas of the SARS-CoV-2 genome

Study unravels gene expression control mechanism with immunity and cancer implications

Modification in some RNA molecules could protect against non-alcoholic fatty liver

Rapid, more accurate test to detect antibodies against SARS-CoV-2 spike protein

Study discloses neuroprotective properties of aromatic turmerone and its derivatives

New technique to quantify resistance levels of plants to microbial pathogens

Driving Support for Pharmaceutical Testing Through Continuous Innovation

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