Molecular & Structural Biology

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Experts decode the genetic mechanism governing the speed of mRNA translation

The genetic material of all eukaryotic organisms is stored in the cell nucleus in the form of DNA. The DNA is first transcribed into messenger RNA in the cell cytoplasm and later translated into protein using ribosomes for it to be used, where ribosomes are small machines capable of decoding messenger RNA to synthesize the relevant proteins.

1 Sep 2021

Study details how immature innate lymphoid cells become effector cells

During the invasion of pathogens into the human body, a prompt response is needed.

1 Sep 2021

Study employs inflammatory proteins to diagnose the early onset of Alzheimer’s

According to recent research, investigating some inflammatory proteins will enable diagnosis of the earlier onset and progression of Alzheimer’s disease.

31 Aug 2021

Study reveals mechanisms promoting overall glioma tumor growth

Researchers from Northwestern Medicine unearthed the epigenetic processes involved in the regulation of multiple oncogenes in glioma cells.

31 Aug 2021

Researchers fabricate 3D-integrated nanopores to detect single DNA molecules

Detecting DNA from a single cell is vital for the identification of genetic disorders and diseases.

From Osaka University 31 Aug 2021

Stanford researchers use machine learning approach to solve structural biology challenges

Determining the 3D shapes of biological molecules is one of the hardest problems in modern biology and medical discovery. Companies and research institutions often spend millions of dollars to determine a molecular structure – and even such massive efforts are frequently unsuccessful.

27 Aug 2021

Old habit-controlling neurons may also play a key role in learning new tricks

Imagine working on your computer and typing the same long password you have used for years to access your email.

26 Aug 2021

Researchers develop a method to engineer new functionalities into cells

Researchers at the Institute of Molecular Biology and Johannes Gutenberg University Mainz have developed a method to engineer new functionalities into cells. The results were published today in the journal Cell in the article "Dual film-like organelles enable spatial separation of orthogonal eukaryotic translation".

26 Aug 2021

Researchers create world's smallest mechanically interlocked biological structure

Researchers at Princeton University have built the world's smallest mechanically interlocked biological structure, a deceptively simple two-ring chain made from tiny strands of amino acids called peptides.

25 Aug 2021

Study unravels new aspects of prions causing untreatable neurodegenerative conditions

A new study achieved the highest-ever resolution imaging of an infectious prion, offering atomic-level data of how these abnormal proteins assemble.

25 Aug 2021

Researchers use DNA barcoding to authenticate 'wild mushrooms' in food products

Harvesting wild mushrooms requires an expert eye to distinguish between the delicious and the inedible. Misidentification can have a range of consequences, from a disgusting taste and mild illness to organ failure and even death.

From The University of Utah 24 Aug 2021

Genome editing tool used to render male mosquitoes infertile and slow disease spread

Mosquitos spread viruses that cause potentially deadly diseases such as Zika, dengue fever and yellow fever. New U.S. Army-funded research uses gene editing to render certain male mosquitoes infertile and slow the spread of these diseases.

24 Aug 2021

Scientists isolate monoclonal antibodies against alphaviruses

A research group has isolated monoclonal antibodies that, in laboratory and animal studies, prohibited infection by alphaviruses.

From Vanderbilt University 24 Aug 2021

Study finds the link between circular RNA and alternative splicing in gastric cancer

At the Chinese Academy of Sciences, scientists have now come up with a mechanism used by circular RNA to inhibit the metastasis of gastric cancer cells.

23 Aug 2021

Study discovers Parkinson’s disease-linked protein impairs mitochondria

Recently, researchers discovered that a protein linked with Parkinson’s disease can impair mitochondria.

23 Aug 2021

Researchers discover how glycans act as gateways for SARS-CoV-2 entry

Since the early days of the COVID pandemic, scientists have aggressively pursued the secrets of the mechanisms that allow severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to enter and infect healthy human cells.

From UC San Diego 20 Aug 2021

New mouse line reveals the state of proteostasis in mammalian brain for the first time

Proteins are the "tools" of our cells – they are essential to all vital tasks. However, they are only able to do their jobs if they fold correctly and adopt their respective, very specific 3D structure.

20 Aug 2021

Researchers reveal how ubiquitous signaling molecule plays a critical role in male fertility

Mammalian sperm cannot fertilize an egg from the get-go. It's an ability acquired only after insemination, during passage through the female reproductive tract, and requires two consecutive, time-sensitive processes to provide sperm with the physical and biochemical traits necessary to complete their fundamental job.