Molecular & Structural Biology

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Study reveals RNA regulatory mechanisms within transcription-translation couplings

To gain a better understanding of how bacterial RNA gives rise to proteins scientists are now focusing on the special way this process takes place in bacteria.

15 Apr 2021

Ebola virus protein changes shape by using human RNA

The human genome contains the instructions to make tens of thousands of proteins. Each protein folds into a precise shape--and biologists are taught that defined shape dictates the protein's destined function. Tens of thousands of singular shapes drive the tens of thousands of needed functions.

15 Apr 2021

Study reveals DNA supercoiling is involved in regulating gene expression

The (when stretched) two-meter-long DNA molecule in each human cell is continuously being unpacked and packed again to enable the expression of genetic information.

15 Apr 2021

New method helps map the epigenetics of mouse brain

Histones are essentially small proteins that attach to DNA and store information that can be used to switch individual genes on or off.

14 Apr 2021

Novel test detects HIV reservoir in patients more accurately

An innovative test that determines the quality and quantity of inactive HIV viruses in the genes of HIV patients may ultimately give scientists a better idea of effective drugs.

14 Apr 2021

Scientists engineer probiotic yeast to produce beta-carotene in the guts of mice

Researchers have genetically engineered a probiotic yeast to produce beta-carotene in the guts of laboratory mice. The advance demonstrates the utility of work the researchers have done to detail how a suite of genetic engineering tools can be used to modify the yeast.

13 Apr 2021

Study compares effect of vaping and smoking on cells and DNA

Researchers have compared vape e-liquid samples and their aerosols to combustible cigarette smoke using Toxys’ ToxTracker range of in-vitro assays.

12 Apr 2021

Study shows how nitrate presence controls nodule formation in legumes

Legumes, or plants belonging to the bean family, form nodules on their roots to absorb nitrogen.

12 Apr 2021

Study explains molecular mechanisms of drug resistance in Mycobacterium tuberculosis

A group of researchers from France, Germany, Belarus, Japan, and Russia and headed by a scientist from Skolkovo Institute of Science and Technology (Skoltech) has discovered how Mycobacterium tuberculosis survives in iron-deficient environments by using rubredoxin B (RubB)—a protein that belongs to the rubredoxin family and plays a significant role in adapting to varying environmental conditions.

9 Apr 2021

Mitochondrial DNA mutations reduce death risk in patients with bowel cancer

According to a study, DNA defects in the energy “factories” of a cell increase the chance of survival in patients suffering from bowel cancer.

9 Apr 2021

New technique improves single-cell transcriptomics

With the help of single-cell transcriptomic techniques, researchers can study an unlimited number of individual cells from living organisms one at a time.

8 Apr 2021

Dopamine-releasing brain cells shed light on Parkinson’s disease

Scientists have found that botulinum toxin—commonly known as Botox—can expose the inner workings of the brain, in addition to smoothing out wrinkles.

From New York University (NYU) 7 Apr 2021

Study discovers how some proteins ensure repair of errors introduced during DNA replication

Researchers have discovered how specific proteins ensure the rectification of errors introduced into the DNA when it replicates.

7 Apr 2021

Study demonstrates how DNA-like molecules could have joined to form the origin of life

Nagoya University scientists in Japan have demonstrated how DNA-like molecules could have come together as a precursor to the origins of life.

7 Apr 2021

Researchers take a key step toward new drugs and vaccines for combating COVID-19

Scientists have achieved a huge step toward new vaccines and drugs for fighting against COVID-19.

6 Apr 2021

New blueprint of brain connectivity provides detailed understanding of the basal ganglia

Thousands of our daily activities, from making coffee to taking a walk to saying hello to a neighbor, are made possible through an ancient collection of brain structures tucked away near the center of the cranium.

6 Apr 2021

Novel cell-to-cell communication network helps cancers regrow following genotoxic therapies

In the fight against cancers, activating mutations in the RAS family of genes stand in the way of finding viable treatment options.

6 Apr 2021

Novel, non-invasive biomarker test could help measure, track performance of senolytics

Scientists from Buck Institute have identified and are now developing an innovative, non-invasive biomarker test that could help quantify and track the performance of senolytics—a class of drugs that selectively destroy senescent cells.

5 Apr 2021

Low K777 concentrations inhibit cathepsin L and reduce SARS-CoV-2’s ability to infect host cell lines

For a long time, James McKerrow, MD, PhD, dean of the Skaggs School of Pharmacy and Pharmaceutical Sciences at University of California San Diego, has investigated neglected tropical diseases, which are chronic, disabling parasitic infections mainly affecting the poor and underserved communities in developing nations.

From UC San Diego 5 Apr 2021

Study sheds new light on age-related neurodegenerative disorders

Neurons cannot simulate their DNA and hence they work continuously to repair any damage caused to their genome.

2 Apr 2021

Molecular & Structural Biology

Study reveals RNA regulatory mechanisms within transcription-translation couplings

Ebola virus protein changes shape by using human RNA

Study reveals DNA supercoiling is involved in regulating gene expression

New method helps map the epigenetics of mouse brain

Novel test detects HIV reservoir in patients more accurately

Scientists engineer probiotic yeast to produce beta-carotene in the guts of mice

Study compares effect of vaping and smoking on cells and DNA

Study shows how nitrate presence controls nodule formation in legumes

Study explains molecular mechanisms of drug resistance in Mycobacterium tuberculosis

Mitochondrial DNA mutations reduce death risk in patients with bowel cancer

New technique improves single-cell transcriptomics

Dopamine-releasing brain cells shed light on Parkinson’s disease

Study discovers how some proteins ensure repair of errors introduced during DNA replication

Study demonstrates how DNA-like molecules could have joined to form the origin of life

Researchers take a key step toward new drugs and vaccines for combating COVID-19

New blueprint of brain connectivity provides detailed understanding of the basal ganglia

Novel cell-to-cell communication network helps cancers regrow following genotoxic therapies

Novel, non-invasive biomarker test could help measure, track performance of senolytics

Low K777 concentrations inhibit cathepsin L and reduce SARS-CoV-2’s ability to infect host cell lines

Study sheds new light on age-related neurodegenerative disorders

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