Molecular & Structural Biology

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New approach could speed the search for promising therapies

Assessing a drug compound by its activity, not simply its structure, is a new approach that could speed the search for COVID-19 therapies and reveal more potential therapies for other diseases.

2 Mar 2021

New technique reveals the tricks that cancer cells use to avoid immunotherapies

By harnessing the immune system against cancer, immunotherapies have revolutionized the way some types of cancer are treated. But most patients--across cancer types--do not respond, and in most cases, scientists are at a loss as to why.

2 Mar 2021

CRISPR-Cas9 can safeguard future crops under stress from variable climate conditions

Gene editing technology will play a vital role in climate-proofing future crops to protect global food supplies, according to scientists at The University of Queensland.

2 Mar 2021

Protein kinases may offer a solution to treat HIV patients with immunodeficiency

A new study indicates that protein kinases, which initiate the process that erodes the body’s immunity, significantly contribute to the immunodeficiency in HIV patients. Drugs that block these protein kinases may offer a solution to treating HIV patients whose immunity is not restored by antiretroviral therapy.

2 Mar 2021

Study describes molecular mechanisms of polar growth in plants

Plants grow in two directions: the shoots of plants grow toward the light to make the best use of it, and the roots grow toward the center of the earth into the soil.

2 Mar 2021

Scientists gain new insights into ribosome formation to identify potential drug targets

Ribosome formation is viewed as a promising potential target for new antibacterial agents. Researchers from Charité - Universitätsmedizin Berlin have gained new insights into this multifaceted process.

2 Mar 2021

Study shows how antibodies fight Zika virus

Zika outbreaks are still having lasting effects on children whose mothers were infected with the Zika virus during their pregnancy.

26 Feb 2021

New signaling pathway prevents the overproduction of RNA-protein complexes

Neurodegenerative diseases, such as various forms of senile dementia or amyotrophic lateral sclerosis (ALS), have one thing in common: large amounts of certain RNA-protein complexes (snRNPs) are produced and deposited in the nerve cells of those affected - and this hinders the function of the cells.

26 Feb 2021

Molecular mapping of proteins shows promise for treating cancer

Swedish researchers have published novel molecular mapping of proteins that controls the process of cell division—detecting 300 of these proteins.

25 Feb 2021

Study reveals new functions of ENDOU enzymes

The majority of organisms feature the series of ENDOU enzymes, but despite this fact, the functions of these enzymes have not been properly understood.

25 Feb 2021

Neuronal and glial circuits form loosely coupled super-network within the brain

Tohoku University scientists have shown that neuronal and glial circuits form a loosely coupled super-network within the brain.

25 Feb 2021

DNA origami helps track gene-editing processes

The genetic scissors, known as CRISPR/Cas9, the finding that received a Nobel Prize in Chemistry, occasionally cut in places that they are not intended to target.

24 Feb 2021

Researchers identify a type of RNA as therapeutic target for Huntington's treatment

Huntington's disease is caused by a mutation in the Huntingtin gene (HTT), which appears in adults and features motor, cognitive and psychiatric alterations.

24 Feb 2021

New platform could help treat neurodegenerative diseases using regenerative medicine

Imagine if surgeons could transplant healthy neurons into patients living with neurodegenerative diseases or brain and spinal cord injuries.

24 Feb 2021

New gene-editing technique allows for pre-programming of sequential edits

Researchers from the University of Illinois Chicago have discovered a new gene-editing technique that allows for the programming of sequential cuts -- or edits -- over time.

24 Feb 2021

Environmental DNA can be used to measure genetic diversity of Pacific salmon, trout

Scientists at Oregon State University and the U.S. Forest Service have demonstrated that DNA extracted from water samples from rivers across Oregon and Northern California can be used to estimate genetic diversity of Pacific salmon and trout.

23 Feb 2021

Study reveals specialized mechanism for translation of mitochondrial genome into proteins

An international collaboration among researchers from Finland, Sweden, UK and the USA has captured ribosomes translating messenger RNA expressed from the maternally inherited mitochondrial genome.

23 Feb 2021

Human monoclonal antibodies can act as biological substitute for chemical antibiotics

In the course of a new and groundbreaking study, led by Dr, Natalia Freund and the doctoral candidate Avia Waston at the Sackler Medical Faculty, the research group succeeded in isolating monoclonal antibodies, which hindered the growth of tuberculosis germs in laboratory mice.

23 Feb 2021

Study provides insight into the structure of prion proteins responsible for diseases

Prion diseases are a group of rapidly progressive, fatal and infectious neurodegenerative disorders affecting both humans and animals: Bovine Spongiform Encephalopathy (BSE) or 'mad cow' disease is one of the most famous since in 1996 scientists found that the agent responsible for the disease in cows, is the same agent responsible for the so-called variant Creutzfeldt-Jakob Disease (vCJD), a disease affecting humans.

22 Feb 2021

New tool helps decode the language used by cells

A new tool developed by an multidisciplinary team of mathematicians and biologists from the University of California, Irvine could help decode the language used by cells to interact with each other.

22 Feb 2021

Molecular & Structural Biology

New approach could speed the search for promising therapies

New technique reveals the tricks that cancer cells use to avoid immunotherapies

CRISPR-Cas9 can safeguard future crops under stress from variable climate conditions

Protein kinases may offer a solution to treat HIV patients with immunodeficiency

Study describes molecular mechanisms of polar growth in plants

Scientists gain new insights into ribosome formation to identify potential drug targets

Study shows how antibodies fight Zika virus

New signaling pathway prevents the overproduction of RNA-protein complexes

Molecular mapping of proteins shows promise for treating cancer

Study reveals new functions of ENDOU enzymes

Neuronal and glial circuits form loosely coupled super-network within the brain

DNA origami helps track gene-editing processes

Researchers identify a type of RNA as therapeutic target for Huntington's treatment

New platform could help treat neurodegenerative diseases using regenerative medicine

New gene-editing technique allows for pre-programming of sequential edits

Environmental DNA can be used to measure genetic diversity of Pacific salmon, trout

Study reveals specialized mechanism for translation of mitochondrial genome into proteins

Human monoclonal antibodies can act as biological substitute for chemical antibiotics

Study provides insight into the structure of prion proteins responsible for diseases

New tool helps decode the language used by cells

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