Molecular & Structural Biology

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Advanced explainable AI to solve regulatory instructions encoded in DNA

Researchers at the Stowers Institute for Medical Research, in collaboration with colleagues at Stanford University and Technical University of Munich have developed advanced explainable artificial intelligence (AI) in a technical tour de force to decipher regulatory instructions encoded in DNA.

19 Feb 2021

Cryogenic electron microscopy reveals shape of glutamate transporters involved in neurological diseases

An international research team has uncovered the shape of the glutamate transporter and helps explain how the human brain cells interact with each other.

18 Feb 2021

Study reveals novel antibody binding implicated in liver and breast cancer

In the field of structural biology, certain molecules are so uncommon that they can only be captured with a special set of tools.

18 Feb 2021

A new method for quantitative single-molecule colocalization analysis

WWU researchers develop a new method for quantitative single-molecule colocalization analysis /Study published in Nature Communications.

17 Feb 2021

Regular caffeine intake can change gray matter of the brain

Coffee, cola, or an energy drink: caffeine is the world's most widely consumed psychoactive substance. Researchers from the University of Basel have now shown in a study that regular caffeine intake can change the gray matter of the brain. However, the effect appears to be temporary.

17 Feb 2021

Potassium-independent cesium transporters in plants can help during nuclear power plant accidents

In recent time, HBO's highly acclaimed and award-winning miniseries Chernobyl highlighted the horror of nuclear power plant accident, which happened in Ukraine in 1986.

17 Feb 2021

Tumor microenvironment could improve cancer immunotherapy

A study has revealed how chemicals surrounding tumors, the tumor microenvironment, undermine the immune system and allow cancer to resist attack.

From University of Pittsburgh 16 Feb 2021

Study shows American plant could be beneficial for balanced, sustainable diet

Researchers have discovered a plant native to America could also be grown in the United Kingdom, bringing with it benefits for a sustainable and balanced diet.

16 Feb 2021

Proprioceptive neurons perform sensory functions in all human body movements

Scientists have unveiled a range of proprioceptive neurons and have uncovered a new form of plasticity, indicating neuronal individuality in the nervous system.

16 Feb 2021

New understanding of tumor microenvironment could help enhance immunotherapy

A paper published today in Nature shows how chemicals in the areas surrounding tumors--known as the tumor microenvironment--subvert the immune system and enable cancer to evade attack. These findings suggest that an existing drug could boost cancer immunotherapy.

From University of Pittsburgh 16 Feb 2021

Antioxidant in green tea may lead to new anti-cancer drugs

Green tea contains an antioxidant that may boost the concentrations of p53, called the “guardian of the genome,” for its potential to kill cancerous cells.

15 Feb 2021

Study reveals the structure of heat shock proteins that could treat Huntington's disease

In Huntington's disease, a faulty protein aggregates in brain cells and eventually kills them. Such protein aggregates could, in principle, be prevented with a heat shock protein.

15 Feb 2021

Electrochemical sensor for rapid detection of multiple sepsis biomarkers in whole blood

Many life-threatening medical conditions, such as sepsis, which is triggered by blood-borne pathogens, cannot be detected accurately and quickly enough to initiate the right course of treatment.

15 Feb 2021

Researchers use mouse models to explain how cancer cells spread

Most tumors consist of a heterogenous mix of cells. Genetic mutations found only in some of these cells are known to aid with the spread and progression of cancer.

15 Feb 2021

Study reveals a new role of SRC-3 protein in various cancers

New research has revealed a new role of the steroid receptor coactivator 3, also called SRC-3/NCOA3.

15 Feb 2021

New AI-based method produces new diversity of AAV capsids for optimized gene therapy

Dyno Therapeutics has demonstrated the use of AI to created an unparalleled range of adeno-associated virus capsids that can evade the immune system.

15 Feb 2021

Enzyme in fruit fly larvae plays key role in waking up brain stem cells

Researchers studying an enzyme in fruit fly larvae have found that it plays an important role in waking up brain stem cells from their dormant 'quiescent' state, enabling them to proliferate and generate new neurons.

12 Feb 2021

Researchers identify protein sequences that might be used by SARS-CoV-2 to infect cells

Researchers at EMBL Heidelberg have identified sequences in human proteins that might be used by SARS-CoV-2 to infect cells. They have discovered that the virus might hijack certain cellular processes, and they discuss potentially relevant drugs for treating COVID-19.

12 Feb 2021

Cell cycle of cancer cells can be disrupted using two commercially available inhibitors

With two commercially available inhibitors, the cell cycle of the cancer cells in the childhood tumor neuroblastoma can be disrupted at a key point causing tumor cell death.

12 Feb 2021

New way to quantify the key characteristics of RNA-binding proteins

A research team from Case Western Reserve University has discovered a new way to quantify the main characteristics of proteins that bind to RNA in cells—a finding that may enhance one’s interpretation of how gene regulation is disrupted in infections, neurodegenerative diseases, or cancer.

11 Feb 2021

Molecular & Structural Biology

Advanced explainable AI to solve regulatory instructions encoded in DNA

Cryogenic electron microscopy reveals shape of glutamate transporters involved in neurological diseases

Study reveals novel antibody binding implicated in liver and breast cancer

A new method for quantitative single-molecule colocalization analysis

Regular caffeine intake can change gray matter of the brain

Potassium-independent cesium transporters in plants can help during nuclear power plant accidents

Tumor microenvironment could improve cancer immunotherapy

Study shows American plant could be beneficial for balanced, sustainable diet

Proprioceptive neurons perform sensory functions in all human body movements

New understanding of tumor microenvironment could help enhance immunotherapy

Antioxidant in green tea may lead to new anti-cancer drugs

Study reveals the structure of heat shock proteins that could treat Huntington's disease

Electrochemical sensor for rapid detection of multiple sepsis biomarkers in whole blood

Researchers use mouse models to explain how cancer cells spread

Study reveals a new role of SRC-3 protein in various cancers

New AI-based method produces new diversity of AAV capsids for optimized gene therapy

Enzyme in fruit fly larvae plays key role in waking up brain stem cells

Researchers identify protein sequences that might be used by SARS-CoV-2 to infect cells

Cell cycle of cancer cells can be disrupted using two commercially available inhibitors

New way to quantify the key characteristics of RNA-binding proteins

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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