Molecular & Structural Biology

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Scientists find sensor protein which enables normal functioning of bladder

A team co-led by scientists at Scripps Research has found that the main sensor protein enabling our sense of touch also underlies the feeling of having a full bladder and makes normal bladder function possible.

15 Oct 2020

Study sheds light on whether corals are genetically equipped to handle warmer oceans

In 1998, ocean temperatures soared, and the world experienced its first significant coral bleaching event. From the Great Barrier Reef to Indonesia to Central America, corals turned white and ghostly.

15 Oct 2020

Researchers unravel molecular factors that drive severity of COVID-19

While most COVID-19 cases are asymptomatic or mild, severe complications associated with acute respiratory distress have led to more than one million deaths worldwide in just several months.

14 Oct 2020

Research focuses on understanding production of memory B cells and immune responses

The current COVID-19 climate has made vaccines, antibodies, and immune responses topics of everyday conversation. Now, it isn't just immunologists who want to know how our bodies respond to re-infections months, years, or sometimes decades after an initial immune response.

From Osaka University 13 Oct 2020

Two proteins compete to give shape to plants

In an elegant choreography, plants take cues from their environment and channel them into flowers, roots, or branches.

13 Oct 2020

Enzyme SSH1 impairs disposal of damaged tau and mitochondria leaking toxins

In a healthy brain, the multistep waste clearance process known as autophagy routinely removes and degrades damaged cell components - including malformed proteins like tau and toxic mitochondria.

13 Oct 2020

Oncopig fulfills the unmet clinical modeling needs for hepatocellular carcinoma

Volume 11, Issue 28 of Oncotarget features "Development and comprehensive characterization of porcine hepatocellular carcinoma for translational liver cancer investigation" by Gaba et, al. which reported that reliable development of Oncopig HCC cell lines was demonstrated through hepatocyte isolation and Cre recombinase exposure across 15 Oncopigs.

12 Oct 2020

Scientists discern molecular mechanisms underlying plant parasitism and cross-species grafting

Using the model Orobanchaceae parasitic plant Phtheirospermum japonicum, scientists from Nagoya University and other research institutes from Japan have discerned the molecular mechanisms underlying plant parasitism and cross-species grafting, pinpointing enzyme β-1,4-glucanase (GH9B3) as an important contributor to both phenomena.

12 Oct 2020

Future ocean warming and acidification could cause physical changes in marine mussels

The increased temperature and acidification of our oceans over the next century have been argued to cause significant physical changes in an economically important marine species.

12 Oct 2020

UMD researchers use AI tools to predict how and when proteins form different shapes

By applying natural language processing tools to the movements of protein molecules, University of Maryland scientists created an abstract language that describes the multiple shapes a protein molecule can take and how and when it transitions from one shape to another.

12 Oct 2020

Scientists shed light on immune evasion strategy used by malaria-causing parasite

The Plasmodium parasite, which transmits malaria to humans through infected mosquitos, triggers changes in human genes that alter the body's adaptive immune response to malarial infections, according to a team of researchers at NYU Abu Dhabi.

12 Oct 2020

New radioimmunotherapy effectively reverses resistance to lymphoma therapy

A new radioimmunotherapy has proven effective in reversing resistance to the most commonly used lymphoma drug, rituximab, according to research published in the October issue of The Journal of Nuclear Medicine.

9 Oct 2020

Too many genetic exchanges impede chromosome segregation into eggs

The exchange of DNA between chromosomes during the early formation of sperm and egg cells normally is limited to assure fertility.

9 Oct 2020

New approach to determine the structure of large RNA molecules

Researchers have designed a new technique to establish the structures of huge RNA molecules at high resolution.

9 Oct 2020

Researchers demonstrate mysterious molecular concept for targeted drug delivery

Researchers have demonstrated a type of cellular binding that could lead to highly targeted treatments against diseases like cancer.

8 Oct 2020

New method reveals structural data of membrane proteins in explicit detail

The human body contains a vast number of proteins that are collectively called the proteome.

8 Oct 2020

New machine learning algorithms to analyze reams of RNA-based 'toehold' sequences

DNA and RNA have been compared to "instruction manuals" containing the information needed for living "machines" to operate.

7 Oct 2020

Maternal high sugar diet can impact developmental outcomes in infants

A diet high in sugar during adulthood is associated with weight gain, and has also been linked to risk of type 2 diabetes, fatty liver disease, and heart disease. New research shows that when consumed by moms during the breastfeeding period, a high sugar diet can also impact developmental outcomes during infancy.

7 Oct 2020

Researchers investigate the role of auxin in regulating pathogen gene expression

Scientists have long known that the plant hormone auxin controls many aspects of plant growth, development, and responses to the environment. Only more recently have they begun to understand that there is also a link between auxin and leaf spotting diseases.

7 Oct 2020

New method can help test vaccine formulations

Scientists are casting a net for nanoparticles. They have now identified a new technique for producing nanoparticles from a simple, self-assembling polymer.

6 Oct 2020

Molecular & Structural Biology

Scientists find sensor protein which enables normal functioning of bladder

Study sheds light on whether corals are genetically equipped to handle warmer oceans

Researchers unravel molecular factors that drive severity of COVID-19

Research focuses on understanding production of memory B cells and immune responses

Two proteins compete to give shape to plants

Enzyme SSH1 impairs disposal of damaged tau and mitochondria leaking toxins

Oncopig fulfills the unmet clinical modeling needs for hepatocellular carcinoma

Scientists discern molecular mechanisms underlying plant parasitism and cross-species grafting

Future ocean warming and acidification could cause physical changes in marine mussels

UMD researchers use AI tools to predict how and when proteins form different shapes

Scientists shed light on immune evasion strategy used by malaria-causing parasite

New radioimmunotherapy effectively reverses resistance to lymphoma therapy

Too many genetic exchanges impede chromosome segregation into eggs

New approach to determine the structure of large RNA molecules

Researchers demonstrate mysterious molecular concept for targeted drug delivery

New method reveals structural data of membrane proteins in explicit detail

New machine learning algorithms to analyze reams of RNA-based 'toehold' sequences

Maternal high sugar diet can impact developmental outcomes in infants

Researchers investigate the role of auxin in regulating pathogen gene expression

New method can help test vaccine formulations

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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