Molecular & Structural Biology

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CAR T cell therapy can predict treatment outcomes in patients with large B-cell lymphoma

Scientists have identified cellular and molecular features of anti-CD19 CAR T cell infusion products that are correlated with large B-cell lymphoma (LBCL).

6 Oct 2020

High folic acid levels during pregnancy affect brain development of mouse embryos

A UC Davis MIND Institute study of pregnant mice found that high amounts of folic acid during pregnancy harmed the brain development of embryos.

From The University of California, Davis 6 Oct 2020

Cancer mutations occur in distinct patterns based on 3D structure of the genome

A new study from researchers at The University of Texas MD Anderson Cancer Center has discovered that mutations found in cancers do not accumulate randomly, but are found in distinct patterns that vary based on the three-dimensional organization of the genome in the cell as well as the underlying factors causing the mutations.

6 Oct 2020

Researchers identify small molecules that appear to reduce cellular stress

For many, getting older can unfortunately mean an increased risk of illness from cardiovascular disease to cancer. University of Michigan scientists are actively researching the biological underpinnings of aging with the aim of developing interventions that could potentially help people live longer, healthier lives.

6 Oct 2020

Researchers use physics to map the chaos of movement in living organisms

The behavior of living organisms might obey the same mathematical laws as physical phenomena, such as weather and the motion of planets, says new research from the Biological Physics Theory Unit at the Okinawa Institute of Science and Technology Graduate University.

6 Oct 2020

Researchers identify new DNA fragment that forms male sex organs in mice

Researchers have identified a new piece of DNA that is crucial for the formation of male sex organs. This discovery may require the revisal of biology textbooks.

5 Oct 2020

Study shows patients can benefit from personalized cancer therapy

Scientists have shown that patients, who are receiving care for cancer, have a greater chance of surviving if they received personalized cancer treatment.

From UC San Diego 5 Oct 2020

Study offers explanation to why people respond differently to the same drug

Scientists at Scripps Research have comprehensively mapped how a key class of proteins within cells regulates signals coming in from cell surface receptors.

5 Oct 2020

Researchers gain insight into potentiating effect of selective drugs

Some highly selective drugs cause unexpected effects in nerve cells: they not only reduce the activation of certain receptors, but also their inactivation.

5 Oct 2020

Type and direction of force on a cell can alter gene expression

Tissues and cells in the human body are subjected to a constant push and pull - strained by other cells, blood pressure and fluid flow, to name a few.

5 Oct 2020

Researchers map genetic networks controlling human regulatory T cell identity

Unlike most T cells, which launch immune responses against foreign molecules, regulatory T cells are the peacekeepers of the human immune system, damping down inflammatory reactions when they're not needed.

5 Oct 2020

Researchers develop a new technique to improve treatment for pancreatic cancer

Scientists have described the individual cells comprising the pancreatic cancer microenvironment.

5 Oct 2020

Researchers identify small molecules that target a structure within SARS-CoV-2 genome

SARS-CoV-2 is a virus that is responsible for causing COVID-19. This pathogen has now crippled economies, health care systems, and everyday lives across the world.

5 Oct 2020

Fungus in some organic pesticides can cause severe cob rot in maize

Protecting crops against pests and diseases is essential to ensure secure food supply. Around 95 percent of the food comes from conventional agriculture, which uses chemical pesticides to keep crops healthy. Increasingly, however, organic pesticides are also being sought as an alternative.

1 Oct 2020

Researchers identify key molecules that contribute to radioresistance in glioblastoma

Scientists have identified key molecules that mediate radioresistance in glioblastoma multiforme; these molecules are a potential target for the treatment of this brain cancer.

1 Oct 2020

Researchers identify a new method to synthesize miniaturized antibodies

Scientists have identified a new method to synthesize miniaturized antibodies, paving the way for a promising new class of therapies for various diseases.

From University of Bath 30 Sep 2020

Genetic factor enables regeneration of adult skin like a newborn's

A newly identified genetic factor allows adult skin to repair itself like the skin of a newborn babe. The discovery by Washington State University researchers has implications for better skin wound treatment as well as preventing some of the aging process in skin.

30 Sep 2020