CloneSelect® Imager FL is a novel fluorescent imaging technology that ensures automated confluence and monoclonality in a variety of cell types.
A cutting-edge method for quick and accurate gene edit identification and monoclonality verification is presented by the CloneSelect® Imager FL. High-contrast multichannel fluorescent and white light imaging are combined to guarantee precise single-cell identification starting on day 0.
With its high-throughput capability, this innovative system streamlines workflows and makes comparative confluence assays easier. It enables researchers to efficiently confirm gene edits and monoclonality, improving cell line development speed and accuracy.
Benefits
Demonstrated IND Success
The Monoclonality Report feature simplifies generating necessary documentation for regulatory agencies. Reports are automatically created according to user-defined parameters. This audit-ready document aids in the submission of an Investigational New Drug (IND) Application to the FDA, adhering to regulations outlined in 21 CFR Part 312.
Multichannel imaging and automated confluence
Algorithms handle different cell types and conditions and are optimized for accurate cell detection. Monoclonality assurance and automatic confluence analysis are provided by publication-ready high-resolution imaging.
Rapid single-cell confirmation
With imaging a 96-well plate in as little as two minutes, the imager offers industry-leading acquisition times. It can also use fluorescence to confirm monoclonality from day zero.
Features
- White light and fluorescence imaging: Provides fast, comprehensive imaging using both fluorescence and white light for improved assessment of cell confluence and monoclonality.
- Data tools to accelerate research timelines: Data tools to accelerate research timelines simplify the process of developing cell lines by integrating growth curve generation and automatic confluence calculations, which streamlines the imaging to IND filing stages.
- Quickly image a variety of plate formats and cell types: Effectively images a 96-well plate in under two minutes, suitable for CHO and HEK among other cell types.
- Intelligent analysis with easy-to-use software: Offers automatic confluence computation at every time interval, generating thorough growth analysis with an easy-to-use interface that requires little training.
- High-resolution images: Combines high-resolution white light imaging with high-speed fluorescence to provide long-term data tracking and precise single-cell detection.
- Custom automation options: Provides customized automation solutions to meet a range of research needs, including drug toxicity research and iPSC studies. These solutions range from basic robotic plate loading to sophisticated workstations.