Genetics and Genomics News and Research

Latest Genetics and Genomics News and Research

Scientists identify molecular mechanisms of IFN responses in COVID-19 disease

SARS-CoV-2 continues to cause an ongoing pandemic as of October 2020, with over 35 million reported cases and over 1 million deaths around the world.

13 Oct 2020

Researchers identify mechanism that silences “parasitic” DNA-elements in pluripotent stem cells

Every eukaryotic organism contains the so-called transposons, which are abundant DNA-elements.

13 Oct 2020

Severe cases of COVID-19 resemble systemic lupus erythematosus

Scientists from Emory Health Sciences have been observing an intense stimulation of immune cells in severe cases of COVID-19 disease. This activation of immune cells is similar to acute flares of systemic lupus erythematosus (SLE)—an autoimmune disease.

13 Oct 2020

Oncopig fulfills the unmet clinical modeling needs for hepatocellular carcinoma

Volume 11, Issue 28 of Oncotarget features "Development and comprehensive characterization of porcine hepatocellular carcinoma for translational liver cancer investigation" by Gaba et, al. which reported that reliable development of Oncopig HCC cell lines was demonstrated through hepatocyte isolation and Cre recombinase exposure across 15 Oncopigs.

12 Oct 2020

Scientists discern molecular mechanisms underlying plant parasitism and cross-species grafting

Using the model Orobanchaceae parasitic plant Phtheirospermum japonicum, scientists from Nagoya University and other research institutes from Japan have discerned the molecular mechanisms underlying plant parasitism and cross-species grafting, pinpointing enzyme β-1,4-glucanase (GH9B3) as an important contributor to both phenomena.

12 Oct 2020

Scientists develop UK Crop Microbiome Cyrobank to facilitate sustainable yield improvement

Scientists from the UK's foremost agricultural research institutes have teamed up to create a new UK Crop Microbiome Cyrobank (UK-CMCB) to safeguard future research and facilitate the sustainable yield improvement of the UK's six major food crops including barley, oats, oil seed rape, potato, sugar beet and wheat.

12 Oct 2020

Researchers examine cooperative tumorigenic effects of targeted deletions of tumor suppressors

Volume 11, Issue 28 of Oncotarget features "Genetic analysis of the cooperative tumorigenic effects of targeted deletions of tumor suppressors Rb1, Trp53, Men1, and Pten in neuroendocrine tumors in mice" by Xu et, al. which reported that the authors examined whether the TSGs Rb1, Trp53, Pten, and Men1 have cooperative effects in suppressing neuroendocrine tumors in mice.

12 Oct 2020

Genomes provide insights into fig-wasp coevolution

Banyan trees are fig trees that begin their life as an epiphyte. The most noticeable feature of banyan Ficus species is their extraordinary aerial roots, which enable them to live as hemi-epiphytes, as do the strangler figs often seen in tropical forests.

12 Oct 2020

Scientists shed light on immune evasion strategy used by malaria-causing parasite

The Plasmodium parasite, which transmits malaria to humans through infected mosquitos, triggers changes in human genes that alter the body's adaptive immune response to malarial infections, according to a team of researchers at NYU Abu Dhabi.

12 Oct 2020

UroCAD assay shows better sensitivity than urine cytology in detecting bladder cancer

Analysis of DNA copy number variants (CNVs) in the cells exfoliated in urine showed better sensitivity and similar specificity in detecting urothelial carcinoma compared with urine cytology.

12 Oct 2020

Researchers develop a new assembler for decoding genomes of microbial communities

Researchers from the Center for Algorithmic Biotechnology at St Petersburg University, as part of a group of Russian and American scientists, have developed the metaFlye assembler.

9 Oct 2020

Study offers new insights how the plant tips stay free of virus

Plants are able to keep growing indefinitely because they have tissues made of meristems--plant stem cells--which have the unique ability to transform themselves into the various specialized cells that make up the plant, dividing whenever appropriate and producing new cells of whatever type as needed.

9 Oct 2020

Too many genetic exchanges impede chromosome segregation into eggs

The exchange of DNA between chromosomes during the early formation of sperm and egg cells normally is limited to assure fertility.

9 Oct 2020

Study shows thymoquinone compound selectively kills prostate cancer cells

According to a new study reported in the Oncogene journal, the thymoquinone (TQ) compound selectively destroys prostate cancer cells at advanced phases.

9 Oct 2020

Newly developed biodegradable microneedles deliver genes into the skin

Gene therapy offers an excellent potential for treating specific types of genetic defects and cancer, immunological diseases, infections, and wounds.

9 Oct 2020

Researchers identify specific neurons that may contribute to epileptic seizures

Epilepsy, results from impairment in brain cells and is often treated with drugs that counteract or control the seizures.

9 Oct 2020

Immune cell biomarker may help identify patients at risk for graft-versus-host disease

A recent report published in Science Translational Medicine by MUSC Hollings Cancer Center investigator Sophie Paczesny, M.D., Ph.D., sheds light on immune cell biomarkers that may reveal which patients are most at risk for graft-versus-host disease (GVHD), a life-threatening condition that can arise after hematopoietic stem cell transplantation (HSCT) for treatment of liquid cancers such as leukemia.

8 Oct 2020

Genetics and Genomics News and Research

Latest Genetics and Genomics News and Research

Scientists identify molecular mechanisms of IFN responses in COVID-19 disease

Researchers identify mechanism that silences “parasitic” DNA-elements in pluripotent stem cells

Severe cases of COVID-19 resemble systemic lupus erythematosus

Oncopig fulfills the unmet clinical modeling needs for hepatocellular carcinoma

Scientists discern molecular mechanisms underlying plant parasitism and cross-species grafting

Scientists develop UK Crop Microbiome Cyrobank to facilitate sustainable yield improvement

Researchers examine cooperative tumorigenic effects of targeted deletions of tumor suppressors

Genomes provide insights into fig-wasp coevolution

Scientists shed light on immune evasion strategy used by malaria-causing parasite

UroCAD assay shows better sensitivity than urine cytology in detecting bladder cancer

Researchers develop a new assembler for decoding genomes of microbial communities

Study offers new insights how the plant tips stay free of virus

Too many genetic exchanges impede chromosome segregation into eggs

Study shows thymoquinone compound selectively kills prostate cancer cells

Newly developed biodegradable microneedles deliver genes into the skin

Researchers identify specific neurons that may contribute to epileptic seizures

Immune cell biomarker may help identify patients at risk for graft-versus-host disease

Study offers new treatment strategies for HIV

New algorithm sharpens focus of world's most powerful microscopes

Study confirms genetic link in cerebral palsy

Omics eBook

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

Genetics and Genomics News and Research

Latest Genetics and Genomics News and Research

Omics eBook

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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