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New scalable method to advance maturation of human pluripotent stem cell-derived cardiomyocytes

A Mount Sinai-led team has developed a reproducible and scalable method to advance maturation of human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs)-;cells that support heart muscle contraction, generated in the lab from human stem cell lines-;which researchers say will improve approaches for disease modeling, regenerative therapies, and drug testing.

8 Apr 2022

Primordial germ cell-like cells produced from stem cells undergo gametogenesis to yield normal offspring

Primordial germ cell-like cells (PGCLCs), generated in vitro from the stem cells of rats, undergo gametogenesis in vivo and yield normal rat offspring, a new study demonstrates.

8 Apr 2022

Cell Guidance Systems and Manchester BIOGEL collaborate to launch PODS-PeptiGels for 3D cell culture

Cell Guidance Systems Ltd today announced a collaboration to launch PODS®-PeptiGels®.

From Cell Guidance Systems 5 Apr 2022

Using a microfluidic chip for selection of healthy sperm based on positive rheotaxis

The female genital tract can be a hostile environment for conception. Out of about 100 million sperm, only a few hundred make it to the fallopian tubes.

1 Apr 2022

New BGI research lays groundwork for organ regeneration

Scientists declared the invention of a transgene-free and manageable method to transform pluripotent stem cells into bona fide 8-cell totipotent embryo-like cells.

23 Mar 2022

Residual coffee grounds could help detect small levels of neurotransmitters

There's nothing like a steaming cup of joe to give your morning a quick boost. Now, there's yet another reason to love the beverage.

21 Mar 2022

New database provides extensive information on kinase-associated neural protein phosphorylation

Biological functions rely on accurate cellular communication involving different molecules. Most major signaling pathways involved in such communication, called signal transduction, often involve a family of kinases—enzymes catalyzing the transfer of phosphates between specific substrate molecules.

17 Mar 2022

One-step ELISA experiments

AMSBIO announces the launch of the QuicKey Pro™ range of ELISA kits – new easy-to-use assays that require just one step of washing, and one step of sample addition, resulting in a whole experiment taking only 90 minutes.

15 Mar 2022

The Nucleic Acid Experts – Certified Twice!

BioEcho Life Sciences receives two important hallmarks for its quality management – DIN EN ISO 9001:2015 and DIN EN ISO 13485:2016.

From BioEcho Life Sciences GmbH 10 Mar 2022

Multi-omics approach help researchers study the disparity created by in vitro culture

Citrus is a significant and economically beneficial horticultural crop with nucellar polyembryony, which prevents hybrid offspring from being produced. Citrus is produced mostly through asexual methods like grafting and cuttings.

7 Mar 2022

Two distinct classes of stem cells drive treatment resistance in patients with myelodysplastic syndromes

Researchers from The University of Texas MD Anderson Cancer Center discovered that treatment resistance in patients with myelodysplastic syndromes (MDS) is caused by two distinct classes of stem cells and identified possible therapeutic approaches that target these cells.

3 Mar 2022

Researchers optimize a route for two-step synthesis of antiviral plant protectant

Plant viruses are of great variety and harm. Virus disease pandemics and epidemics were estimated to have a global economic impact in the tens of billions of dollars.

3 Mar 2022

Simple lab model helps investigate the properties of muscle cells from sIBM patients

A team of researchers at Tohoku University have developed a simple lab-based system for growing human muscle cells that are capable of vigorously contracting.

3 Mar 2022

Semarion raises £2.14 million GBP ($2.89 million USD) seed funding

Semarion Ltd, a University of Cambridge spin-out company from the Cavendish Laboratory combining materials engineering and cell biology to tackle unmet drug screening needs, announced today that it has closed a £2.14 million GBP seed funding round.

22 Feb 2022

Experts identify a potential new target for antimalarial development

A protein that plays an important biological role in the malaria-causing parasite has been discovered by an international research team.

18 Feb 2022

Experts trigger apoptosis in leukemia cells by disrupting their energy maintenance mechanism

A group of researchers from UNIGE in Switzerland and Inserm in France has discovered a previously unknown process that could lead to the creation of novel medicines.

18 Feb 2022

New study deepens the understanding of microbial sulfur metabolism

The metabolism of sulfur compounds is among the most important microbial processes sustaining life in many anoxic environments where oxygen is not present.

18 Feb 2022

Illumina partners with centers across France to advance a precision medicine approach for patients with late-stage cancer

Joint study will assess clinical value of comprehensive genomic profiling (CGP) on cancer therapy options in patients with advanced disease

17 Feb 2022

Plant-based nanoparticles likely to provide anti-cancer drug

Nanomaterials have transformed cancer therapy, and plant-derived nanoparticles have the added benefit of being cost-effective and simple to produce in mass.

From Tokyo University of Science 16 Feb 2022

Programming DNA Robots to Prod Cell Membranes

In this interview, we speak to Dr. Matthew Baker about his latest research that led to the programming of DNA 'robots' that are able to prod cell membranes.

From The University of New South Wales (UNSW) 14 Feb 2022

in vitro News and Research

New scalable method to advance maturation of human pluripotent stem cell-derived cardiomyocytes

Primordial germ cell-like cells produced from stem cells undergo gametogenesis to yield normal offspring

Cell Guidance Systems and Manchester BIOGEL collaborate to launch PODS-PeptiGels for 3D cell culture

Using a microfluidic chip for selection of healthy sperm based on positive rheotaxis

New BGI research lays groundwork for organ regeneration

Residual coffee grounds could help detect small levels of neurotransmitters

New database provides extensive information on kinase-associated neural protein phosphorylation

One-step ELISA experiments

The Nucleic Acid Experts – Certified Twice!

Multi-omics approach help researchers study the disparity created by in vitro culture

Two distinct classes of stem cells drive treatment resistance in patients with myelodysplastic syndromes

Researchers optimize a route for two-step synthesis of antiviral plant protectant

Simple lab model helps investigate the properties of muscle cells from sIBM patients

Semarion raises £2.14 million GBP ($2.89 million USD) seed funding

Experts identify a potential new target for antimalarial development

Experts trigger apoptosis in leukemia cells by disrupting their energy maintenance mechanism

New study deepens the understanding of microbial sulfur metabolism

Illumina partners with centers across France to advance a precision medicine approach for patients with late-stage cancer

Plant-based nanoparticles likely to provide anti-cancer drug

Programming DNA Robots to Prod Cell Membranes

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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