Antigen News and Research

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Virus-mimicking drugs may overcome immunotherapy resistance in tumors

Researchers at the UCLA Jonsson Comprehensive Cancer Center have found that a drug that activates the body's natural defenses by behaving like a virus may also make certain stealthy melanoma tumors visible to the immune system, allowing them to be better targeted by immunotherapy.

15 Oct 2020

Immunotherapy using CAR NKT cells shows promise for treating solid tumors

Natural killer T (NKT) cells, a type of immune cells known for their potent anti-cancer properties in murine tumor models, have been developed into a novel form of immunotherapy to treat patients with cancer.

14 Oct 2020

New software helps analyze individual cells in virtual reality

New virtual reality software now enables scientists to “walk” inside and examine individual cells.

14 Oct 2020

Treatment using immune system T cells preserves vision of mice with retinoblastoma

A treatment that uses immune system T cells, combined with an immune-boosting drug packaged in an injectable gel, was found to preserve the vision of mice implanted with tissue from a human eye cancer known as retinoblastoma.

13 Oct 2020

Serum antibodies from recovered SARS patients neutralized SARS-CoV-2 in vitro

Antibodies in serum samples collected from patients infected with SARS-CoV during the 2003 outbreak effectively neutralized SARS-CoV-2 infection in cultured cells, according to a new study.

12 Oct 2020

New radioimmunotherapy effectively reverses resistance to lymphoma therapy

A new radioimmunotherapy has proven effective in reversing resistance to the most commonly used lymphoma drug, rituximab, according to research published in the October issue of The Journal of Nuclear Medicine.

9 Oct 2020

Immune cell biomarker may help identify patients at risk for graft-versus-host disease

A recent report published in Science Translational Medicine by MUSC Hollings Cancer Center investigator Sophie Paczesny, M.D., Ph.D., sheds light on immune cell biomarkers that may reveal which patients are most at risk for graft-versus-host disease (GVHD), a life-threatening condition that can arise after hematopoietic stem cell transplantation (HSCT) for treatment of liquid cancers such as leukemia.

8 Oct 2020

Prostate cancer screening tool leads to fewer biopsies and potential savings

Multiparametric magnetic resonance imaging of the prostate (mpMRIp) is a promising tool for diagnosing prostate cancer, and prior to its availability, detection relied on clinical exams and prostate specific antigen screening.

8 Oct 2020

Scientists identify new ingredient that makes vaccine more effective

A number of vaccines contain ingredients known as adjuvants that make them more effective by triggering a more powerful immune response.

5 Oct 2020

Researchers identify a new method to synthesize miniaturized antibodies

Scientists have identified a new method to synthesize miniaturized antibodies, paving the way for a promising new class of therapies for various diseases.

From University of Bath 30 Sep 2020

Memory training for the immune system

After an infection of the human body with a pathogen, a cascade of reactions will usually be set into motion.

29 Sep 2020

New Dual CAR T cell immunotherapy can help fight against HIV infection

A recent study published in the journal Nature Medicine, led by researchers James Riley, PhD, a professor of Microbiology at the Perelman School of Medicine at the University of Pennsylvania, and Todd Allen, PhD, a professor of Medicine at Harvard Medical School and Group Leader at the Ragon Institute of MGH, MIT and Harvard, describes a new Dual CAR T cell immunotherapy that can help fight HIV infection

24 Sep 2020

New methods to increase anti-cancer activity of T cells

Scientists have gained a deeper insight into the complexity of the surrounding in which T cells flourish.

18 Sep 2020

Study shows how components of body's immune system find intruding cells

Research led by Dr. Wonmuk Hwang has led to a better understanding of how components of the body's immune system find intruding or damaged cells, which could lead to novel approaches to viral and cancer treatments.

17 Sep 2020

T cells play a vital role in controlling SARS-CoV-2 during acute phase of infection

Ever since SARS-CoV-2 first appeared, researchers have been trying to understand whether sometimes the immune system does more harm than good during the acute phase of COVID-19. The latest study by researchers at La Jolla Institute for Immunology clearly argues in favor of the immune system.

17 Sep 2020

Researchers identify the targets of immune rejection

Human pluripotent stem cells (hPSCs) show promise in regenerative medicine for how they lead to the fraction of every other type of cells in the body.

17 Sep 2020

Study pinpoints specific protein involved in the mass production of antibodies

A team of researchers has discovered how a specific protein called JAGN1 plays a crucial role in the production of antibodies.

17 Sep 2020

Antibody profile differentiates non-celiac gluten sensitivity from celiac disease

A new study of the antibodies produced by people with gluten sensitivity may lead to a better way to detect the condition and treat it.

1 Sep 2020

Researchers identify new pathway that targets common vulnerability in different pandemic viruses

Researchers working in human cells have identified a new pathway that targets a common vulnerability in several different pandemic viruses.

28 Aug 2020

Scientists identify antigen valencies that work best in vaccine designs for HIV, SARS-CoV-2

Designing a vaccine starts with finding the right ingredients. Every infectious agent has molecules, called antigens, that the immune system could potentially recognize and attack. So scientists must carefully consider which antigens should go into a vaccine.

28 Aug 2020

Antigen News and Research

Virus-mimicking drugs may overcome immunotherapy resistance in tumors

Immunotherapy using CAR NKT cells shows promise for treating solid tumors

New software helps analyze individual cells in virtual reality

Treatment using immune system T cells preserves vision of mice with retinoblastoma

Serum antibodies from recovered SARS patients neutralized SARS-CoV-2 in vitro

New radioimmunotherapy effectively reverses resistance to lymphoma therapy

Immune cell biomarker may help identify patients at risk for graft-versus-host disease

Prostate cancer screening tool leads to fewer biopsies and potential savings

Scientists identify new ingredient that makes vaccine more effective

Researchers identify a new method to synthesize miniaturized antibodies

Memory training for the immune system

New Dual CAR T cell immunotherapy can help fight against HIV infection

New methods to increase anti-cancer activity of T cells

Study shows how components of body's immune system find intruding cells

T cells play a vital role in controlling SARS-CoV-2 during acute phase of infection

Researchers identify the targets of immune rejection

Study pinpoints specific protein involved in the mass production of antibodies

Antibody profile differentiates non-celiac gluten sensitivity from celiac disease

Researchers identify new pathway that targets common vulnerability in different pandemic viruses

Scientists identify antigen valencies that work best in vaccine designs for HIV, SARS-CoV-2

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