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New method for mapping the structures of heparan sulfate sugars

Heparin, the blood-thinning drug, is used worldwide. However, to date, mapping of the fundamental sugar structures of heparin and the wider class of heparan sulfate sugars in cells has not been accomplished.

23 Mar 2020

Hero proteins can prevent dangerous clumps linked with neurodegenerative diseases

At the University of Tokyo (UTokyo), scientists have identified a new group of proteins that have been hailed for their extraordinary shape and potential to defend against protein clumps linked with neurodegenerative diseases in laboratory experiments.

13 Mar 2020

Biochemical, analytical high-throughput methods used to map proteome of plants

Plants play a crucial role in the survival of life on earth. They offer oxygen for breathing and food for all organisms, as well as regulate the planet’s climate. Proteins are vital in controlling all aspects of life, including plants.

13 Mar 2020

Research on mice shows unexpected effect of intermittent fasting on fat metabolism

Australian scientists have used sophisticated analytical tools to understand the effect of intermittent fasting on the liver to help mitigate disease.

11 Mar 2020

Intact Protein Mass Spectrometry of Cell Culture Harvest Guides Cell Line Development for Trispecific Antibodies

A team in Massachusetts has established a method of profiling of mispairing in antibody assembly.

18 Feb 2020

Mass Spectrometry‐Based Strategies for Therapeutic Antibodies Extensive Characterization and Optimization

For many years’ antibodies have been used in therapeutic applications to treat a plethora of diseases and ailments.

17 Feb 2020

Combining AIMS with machine learning to speed up breast cancer diagnosis

Researchers have conducted a study showing that combining an AIMS approach with machine learning could speed up the diagnosis of breast cancer.

15 Feb 2020

MicroNIR/Chemometrics approach to hemp flour monitoring successfully identifies residual cannabinoid content

Researchers in Italy have developed an innovative new platform that can detect residual cannabinoid content in commercially available hemp flours.

15 Feb 2020

Mass spectrometry analyzing ozonolysis of triacylglycerols determines fingerprint age

Researchers have established a way to determine the age of fingerprints that could help forensic investigators.

14 Feb 2020

Applying integrated lipidomics and proteomics in multiple myeloma reveals potential disease pathways

A team of Australian researchers has confirmed the feasibility and potential of applying integrated lipidomics and proteomics to malignant plasma cells from myeloma patients.

13 Feb 2020

Using nitrogen in place of helium for DART-MS application could be a greener, more convenient alternative

Researchers have revealed a new real-time mass spectrometry protocol for forensic drug screening.

12 Feb 2020

Lipidomics of human adipose tissue reveals diversity between body areas

Scientists have established a lipidomic method that proved successful in the analysis of human subcutaneous adipose biopsies.

11 Feb 2020

Progesterone induces sperm release from oviductal epithelial cells by modifying sperm proteomics

An international team of researchers has uncovered valuable insights on the underlying mechanisms involved in the process of sperm release from the oviduct.

10 Feb 2020