Bioinformatics News and Research

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Bioinformatics is the application of information techniques for the storage, retrieval, and analysis of large quantities of biological data.

Human genetics: New insights into our own biology

Who are we? Where did we come from? How did we get here? Throughout the ages, humans have sought answers to these questions, pursuing wisdom through religion, philosophy, and eventually science.

21 Sep 2020

Developing computational algorithms to enable a closer look at the 3D genome

Breakthrough advances in biomedical technology have come a long way, especially with three-dimensional mapping of the structure of the genome.

14 Sep 2020

Researchers identify the cause for Parkinson's disease and potential treatments

In a seven-year research effort, an international team of scientists has clarified the cause for certain genetic forms of Parkinson's disease, and has identified potential pharmacological treatments.

14 Sep 2020

Researchers develop new tool to predict protein disorder

Nobel Prize winner Christian Boehmer Anfinsen had demonstrated clearly that a protein is capable of finding its way back to its “native” 3D structure.

11 Sep 2020

Researchers develop statistical model that predicts risk of developing esophageal cancer

Globally, esophageal cancer is said to be the eighth most common cancer and it usually develops from a condition known as Barrett’s esophagus.

9 Sep 2020

Zika virus infection during pregnancy can cause severe abnormalities in the fetus

Zika virus infection during pregnancy can cause severe abnormalities in the fetus, including malformations such as microcephaly. In a small proportion of cases, the disease may lead to miscarriage and perinatal death.

4 Sep 2020

Researchers investigate cellular factors that could be significant for COVID-19 infection

An infection with the coronavirus SARS-CoV-2 can affect multiple organs. With this in mind, researchers of the German Center for Neurodegenerative Diseases (DZNE) and Cornell University in the US have investigated cellular factors that could be significant for an infection.

4 Sep 2020

New method accurately detects single gene mutation in a pool of 10,000 cells

Rare genetic mutations occurring in cells cannot be detected by existing sequencing techniques because these methods do not have the required sensitivity.

1 Sep 2020

Scientists publish most comprehensive genome information for major agricultural weeds

Representing some of the most troublesome agricultural weeds, waterhemp, smooth pigweed, and Palmer amaranth impact crop production systems across the U.S. and elsewhere with ripple effects felt by economies worldwide.

28 Aug 2020

Re-designed natural enzyme shows promise in promoting the regrowth of nerve tissue injury

A team of researchers from University of Toronto Engineering and the University of Michigan has redesigned and enhanced a natural enzyme that shows promise in promoting the regrowth of nerve tissue following injury.

From University of Toronto 25 Aug 2020

Study sheds light on inner workings of the human heart

Researchers have investigated the function of a complex mesh of muscle fibers that line the inner surface of the heart.

20 Aug 2020

Switching off 'master regulator' may offer neuroprotection from Parkinson's-related damage

Switching off a molecular "master regulator" may protect the brain from inflammatory damage and neurodegeneration in Parkinson's disease, reports a study published today in Nature Neuroscience.

18 Aug 2020

New research suggests pollution is also a cause for antibiotic resistance

Antibiotic resistance is an increasing health problem, but new research suggests it is not only caused by the overuse of antibiotics. It's also caused by pollution.

From University of Georgia 14 Aug 2020

Adaptive parallel mutations are more common in Lake Baikal amphipods

A group of scientists from Skoltech and the Institute for Information Transmission Problems of RAS (IITP RAS) showed, using Lake Baikal amphipods as an example, that parallel evolution driven by adaptations can be detected at the whole-genome level.

11 Aug 2020

Study may point to new therapeutic options for COVID-19

Contrary to what has been generally assumed so far, a severe course of COVID-19 does not solely result in a strong immune reaction - rather, the immune response is caught in a continuous loop of activation and inhibition.

7 Aug 2020

Study: Amyloid-beta alters cholesterol biosynthesis in early stages of Alzheimer’s

Korea Brain Research Institute (headed by Suh Pann-ghill) announced on July 24 the discovery that an increase in amyloid-beta in the brain alters cholesterol biosynthesis, which was found by Dr. Cheon Mookyung of KBRI through RNA-seq analysis data (omics) using AI.

7 Aug 2020

Deep Learning On Cell Signaling Networks Establishes AI For Single-Cell Biology

Computer systems that emulate key aspects of human problem solving are commonly referred to as AI. This field has seen massive progress over the last years.

6 Aug 2020

Researchers map DNA methylation changes to study developmental disorders

Researchers performed a study in which they created a total of 168 new maps of chemical marks on DNA strands, known as methylation, in developing mice.

30 Jul 2020

Scientists use computational biology to identify functional elements in the human genome

UMass Medical School researchers Zhiping Weng, PhD, and Jill Moore, PhD, and MD/PhD students Michael Purcaro and Henry Pratt are lead authors on the latest publication of data from the ambitious ENCODE project.