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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Advancing the Understanding of Circadian Regulation with Melanopsin DNA Aptamers

DNA aptamers of melanopsin that regulate the clock hands of biological rhythms were developed by the Toyohashi University of Technology and the National Institute of Advanced Industrial Science and Technology (AIST) group.

15 Jul 2024

Macrophage Inflammation may Contribute to LSD Symptoms

Researchers at The Hospital for Sick Children (SickKids) have found that inflammation in an immune cell may be responsible in part for some severe symptoms in a group of rare genetic conditions called lysosomal storage diseases (LSDs).

15 Jul 2024

Surface Plasmon Resonance Sensors: Transforming Drug Development and Clinical Diagnostics

The latest developments in SPR-based biosensors and their applications in drug discovery.

15 Jul 2024

Breakthrough Study Reveals How Toxoplasma gondii Alters Host Cell Metabolism

Toxoplasma gondii is a parasite responsible for toxoplasmosis, a lifelong chronic infection prevalent in about 30% of the human population.

12 Jul 2024

Artificial Intelligence Drives Breakthroughs in Drug Discovery, Reducing Costs and Timelines

Researchers discussed using deep generative AI models and their diverse algorithms in de novo drug design.

12 Jul 2024

AI-Driven Atlas Reveals Hidden Proteins in Cellular Condensates

Scientists at the University of Cambridge have developed an atlas of proteins describing how they behave inside human cells.

11 Jul 2024

New Gene Editing Technique Outperforms Existing Therapies

Cystic fibrosis, a prevalent genetic disorder, leads to thick mucus accumulation in the lungs and other parts of the body, resulting in breathing difficulties and infections.

11 Jul 2024

Kainate Receptors: A Potential Target for Novel Cerebellar Therapies

The Institute of Neurosciences (IN), a collaborative center of the Miguel Hernández University (UMH) of Elche and the Spanish National Research Council (CSIC) is leading a study in Tokyo, Japan, in conjunction with Keio University, which highlights the critical role one of the glutamate receptors plays in the proper functioning of the cerebellum's synapses.

11 Jul 2024

New Insights into ILC2 Development Could Lead to Innovative Therapies for Allergic Diseases

Scientists have discovered a novel mechanism of ILC2 immune cell development which may be involved in exacerbating allergic diseases.

11 Jul 2024

Phage Protein Discovery Holds New Key to Battling Bacteria

An unexpected find has enabled important progress to be made in the battle against harmful bacteria.

11 Jul 2024

UNC-Chapel Hill Study Reveals New Mechanism of Gene Regulation Beyond Histone Modification

University of North Carolina at Chapel Hill researchers have determined whether a specific chemical modification of a protein that packages the genome called a histone affects gene activity and cell proliferation according to the paper, "Drosophila melanogaster Set8 and L(3)mbt function in gene expression independently of histone H4 lysine 20 methylation," published in Genes & Development.

11 Jul 2024

Real-Time Snapshots of RNA Polymerase Illuminate Transcription Bubble Dynamics

Every living cell transcribes DNA into RNA. This process begins when an enzyme called RNA polymerase (RNAP) clamps onto DNA.

10 Jul 2024

Unveiling the Power of mRNA and LNPs in Modern Medicine

Consider a situation in which an expert hacker has to upload vital software to update a central server and stop a potentially fatal virus from causing havoc on a sizable computer network.

10 Jul 2024

Harnessing Proteomics For Food Safety: Allergen Profiling and Food Authenticity Verification

The proteomics-based strategies used to profile food allergies and authenticate food products.

10 Jul 2024

Unveiling Progesterone's Impact on Cancer Immunosuppression

Researchers turned to pregnancy to explore why some cancers successfully evade the immune system and grow unchecked.

9 Jul 2024

A New Tool to Unravel the Mysteries of Metabolic Genes

A novel discovery platform has been created by a multidisciplinary research team to investigate the role of genes involved in metabolism, which is the culmination of all chemical reactions necessary for life.

9 Jul 2024

Comprehensive Analysis Identifies Risk Factors for Multiple Cancers

Scientists have discovered over 5,000 genetic variations that give rise to specific cancers, along with a possible therapeutic target that could be used to treat or even stop these cancers from growing.

8 Jul 2024

Study Reveals Key Genetic Interaction for Enhanced Drought Tolerance in Plants

Drought significantly impacts agricultural productivity and plant survival. Traditional methods for improving drought resistance, such as selective breeding and genetic modification, have had limited success.

5 Jul 2024

Unveiling the Role of Exons in Protein Foldability and Evolution

A new study led by Rice University's Peter Wolynes offers new insights into the evolution of foldable proteins. The research was published in the Proceedings of the National Academy of Sciences.

4 Jul 2024

Innovative Approach to Protein Synthesis Funded by $2 Million Grant

The National Institutes of Health's Maximizing Investigators' Research Award (MIRA) program for established investigators has awarded Rice University chemist Han Xiao with nearly $2 million.

4 Jul 2024