Proteomics News and Research

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The term 'proteome' was first coined in 1994, and refers to all the proteins in a cell, tissue, or organism. Proteomics refers to the study of the proteome. Because proteins are involved in almost all biological activities, the proteome is a rich source of biological information.

Hyperosmotic stress induces phase separation of the proteasomes

Cellular proteostasis is regulated by a crucial proteolytic machine called proteasome via selective degradation of ubiquitylated proteins.

29 Apr 2020

Study shows how DNA mimic protein helps phages to attack their victims

A research team from the Severinov Laboratory at Skoltech, together with their collaborators from Israel and Switzerland, has analyzed a bacterial BREX defense mechanism that was poorly studied to date.

29 Apr 2020

Novel protein sensor controls the pathway of fat and sugar conversion in humans

Researchers in Pennsylvania and Texas have discovered a novel protein sensor that limits the amounts of fat and sugar that are converted into energy by human cells, during the starvation periods.

27 Apr 2020

Developing novel compounds that inhibit SARS-CoV-2 main protease

A research team from China has now created two novel compounds that block the SARS-CoV-2 main protease (Mpro).

23 Apr 2020

Preventing viral infections by protein shell misassembly

A study published recently in eLife reports new understanding of conditions that govern self-assembly in the protective shell of viruses.

23 Apr 2020

Mitochondrial protein contributes to degenerative diseases

Scientists and their collaborators from Duke-NUS Medical School (Duke NUS) have recently identified a novel small protein in mitochondria, which is essential for energy production.

17 Apr 2020

New method images proteins in 3D with nanoscale resolution

A research team, which also included scientists from the National Synchrotron Light Source II (NSLS-II), has reported a novel method for imaging proteins in three dimensions (3D) with nanoscale resolution.

16 Apr 2020

Metals can affect the formation of harmful misfolded peptide clusters in various diseases

Revealing the interactions between metal ions and peptides in the body could help develop enhanced treatments for Alzheimer’s diabetes, and other diseases.

14 Apr 2020

Novel isomer separation technique has major implications in biological processes

Proteins are composed of long chains of amino acids, and a majority of these proteins have one or more methionine—a sulfur-containing amino acid.

From University of California Santa Cruz 13 Apr 2020

Protein interaction study could shed light on the mechanism behind various diseases

The human body is made of billions of cells, and each cell is formed and maintained through innumerable interactions of its molecular parts.

9 Apr 2020

Study designs artificial proteins that function as molecular logic gates

Researchers are currently using the same fundamental tools that enable the working of computers to manipulate life at the molecular level.

6 Apr 2020

Protein Abundant In The Heart Plays Key Role In Blood Clotting

Heart protein cardiac myosin, which is released into the body when a person suffers a heart attack, can cause blood to thicken or clot.

3 Apr 2020

Hidden Messages In Protein Blueprints

Scientists from DKFZ, HI-STEM have identified a new control mechanism that enables stem cells to adapt their activity in emergency situations.

2 Apr 2020

Cellular Protein Shredders For The Fight Against Cancer

An international team of researchers has investigated how a cell's own "protein shredder" can be specifically programmed to fight cancer.

2 Apr 2020

New strategy can help treat diabetes and other diseases

Transplanted islet cells that release insulin during very low blood sugar levels offer a potential way for treating diabetes.

From Massachusetts Institute of Technology (MIT) 31 Mar 2020

Biochemical, analytical high-throughput methods used to map proteome of plants

Plants play a crucial role in the survival of life on earth. They offer oxygen for breathing and food for all organisms, as well as regulate the planet’s climate. Proteins are vital in controlling all aspects of life, including plants.

13 Mar 2020

Applying integrated lipidomics and proteomics in multiple myeloma reveals potential disease pathways

A team of Australian researchers has confirmed the feasibility and potential of applying integrated lipidomics and proteomics to malignant plasma cells from myeloma patients.

13 Feb 2020

Progesterone induces sperm release from oviductal epithelial cells by modifying sperm proteomics

An international team of researchers has uncovered valuable insights on the underlying mechanisms involved in the process of sperm release from the oviduct.

10 Feb 2020