Bioinformatics News and Research

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Bioinformatics is the application of information techniques for the storage, retrieval, and analysis of large quantities of biological data.

Study reveals nuanced role for oncogene in contact inhibition

Like subway com muters on a crowded train, cells generally prefer not to be packed in too tightly. In fact, they have set up mechanisms to avoid this, a phenomenon called "contact inhibition."

15 May 2020

Study could help design better methods to create muscle cells from stem cells

A research team has created the world’s first roadmap of the development mechanism of human skeletal muscles, including the development of muscle stem cells.

12 May 2020

Determining effect of drugs in pancreatic islets through single-cell RNA-seq approach

Scientists have developed a technique to assess the impact of particular drugs in pancreatic tissues by using an advanced single-cell RNA sequencing approach.

12 May 2020

How Intensive Farming Could Increase the Risk of Epidemics

Professor Sam Sheppard speaks to AZoLifeSciences about his research on intensive farming and how it could increase the risk of epidemics.

From University of Bath 12 May 2020

Microbiome 'fingerprint' method helps track microbial strains transferred from maternal to infant gut

Microbial communities in the intestine -- also known as the gut microbiome -- are vital for human digestion, metabolism and resistance to colonization by pathogens.

11 May 2020

Bacterial Enzyme Activity Could Lead To New Sugar-Based Drugs

Researchers from DTU Biosustain and DTU Bioengineering have elucidated the activity of the enzyme GH109 whose mechanism of activity has been a mystery.

5 May 2020

Study shows how mutational signatures are shaped by DNA repair pathways

A research team has examined more than 2700 genomes from C. elegans worms to gain a better understanding on the causes responsible for mutations.

4 May 2020

DNA Damage And Faulty Repair Jointly Cause Mutations

Researchers at EMBL-EBI analyzed over 2700 genomes from C. elegans worms in order to better understand the causes of mutations.

4 May 2020

Study shows how DNA mimic protein helps phages to attack their victims

A research team from the Severinov Laboratory at Skoltech, together with their collaborators from Israel and Switzerland, has analyzed a bacterial BREX defense mechanism that was poorly studied to date.

29 Apr 2020

A New Therapeutic Target Turns The Immune System Against Lymphoma

Non-Hodgkin lymphoma (NHL) is a group of cancers that originate in the lymph nodes and affect white blood cells of the immune system called B cells.

24 Apr 2020

Study sheds light on the regulation of microRNAs

In all the organisms, including humans, proteins are encoded by genes and these proteins, in turn, control the body’s diverse specific cellular functions.

24 Apr 2020

Researchers develop new molecular workflow to study single-cell genomics of diseases

Although advances in genetics and genomics reveal numerous disease-associated gene mutations, physicians and researchers still wrestle with the tricky challenge of linking those mutations to actual disease-causing processes.

23 Apr 2020

A novel prediction method for promising antiviral drug or vaccine targets

A novel method to predict the most promising targets for antiviral drugs or vaccines is based on the conformational changes viral glycoproteins go through during the process of recognition and binding to the host cell.

21 Apr 2020

Unlocking New Ways To Understanding Evolving Strains Of SARS-Cov-2

Researchers from CSIRO have unveiled a new approach to analyzing the genetic codes - or the blueprint - of the SARS-CoV-2 virus that causes COVID-19.

20 Apr 2020

Experience Matters For Immune Cells

The discovery that immune T cells have a spectrum of responsiveness could shed light on how our immune system responds to infections and cancer.

17 Apr 2020

New study on transposable elements could help advance understanding of genetic evolution

There has been very little knowledge of ways in which transposable elements play a role in gene regulation. Transposable elements are small DNA pieces with the ability to replicate and scatter themselves in the genome.

16 Apr 2020

Molecular causes of brain asymmetry revealed

Scientists may have solved one of the most puzzling and persistent mysteries in neuroscience: why some people are "right-brained" while others are "left-brained."

15 Apr 2020

Epigenetic controls of T cells can help treat Type 1 diabetes

At St. Jude Children’s Research Hospital, researchers have generated a database that detects gene-regulatory mechanisms in immune cells that promote Type 1 diabetes.

31 Mar 2020

Biochemical, analytical high-throughput methods used to map proteome of plants

Plants play a crucial role in the survival of life on earth. They offer oxygen for breathing and food for all organisms, as well as regulate the planet’s climate. Proteins are vital in controlling all aspects of life, including plants.

13 Mar 2020